Shohei Ishikawa

Universal Screening for Familial Hypercholesterolemia in Children in Kagawa, Japan

Keiji Matsunaga, Asako Mizobuchi, Hai Ying Fu, Shohei Ishikawa et autres

AIM: Familial hypercholesterolemia (FH) is an underdiagnosed autosomal dominant genetic disorder characterized by high levels of plasma low-density lipoprotein cholesterol (LDL-C) from birth. This study aimed to assess the genetic identification of FH in children with high LDL-C levels who are identified …

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Development of a Novel Algorithm to Detect Atrial Fibrillation Using an Automated Blood Pressure Monitor With an Irregular Heartbeat Detector

Makoto Ishizawa, Takahisa Noma, Takahiro Izumi, Ryosuke Tani et autres

BACKGROUND: Atrial fibrillation (AF), which contributes to an increased risk of stroke, frequently remains undetected, suggesting an unmet need for easier and more reliable AF screening. The reports on screening AF using an Omron blood pressure (BP) monitor with an irregular heartbeat …

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P6578Development of the novel program to diagnose atrial fibrillation using automated blood pressure monitor

Makoto Ishizawa, Takahisa Noma, Shohei Ishikawa, Keiji Matsunaga et autres

Abstract Background Atrial fibrillation (AF) is often asymptomatic and contributes to an increased risk of strokes. The development of proper screening device of AF is unmet medical needs worldwide. Recently, we had reported that multiple measurements using Omron automated blood pressure (BP) …

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P1936Multiple measurements with an automated blood pressure monitor can detect atrial fibrillation with high sensitivity and specificity in general cardiac patients

Makoto Ishizawa, Tomoko Inoue, Atsushi Tobiume, Yusuke Hasui et autres

Background: Atrial fibrillation (AF) is one of the most common arrhythmias and contributes to an increased risk of strokes. Unfortunately, AF frequently remains undetected, suggesting the unmet medical needs of more extended and reliable AF screening. There are several reports to screen …

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Apoptosis inhibitor of macrophage depletion decreased M1 macrophage accumulation and the incidence of cardiac rupture after myocardial infarction in mice

Shohei Ishikawa, Takahisa Noma, Hai Ying Fu, Takashi Matsuzaki et autres

BACKGROUND: Cardiac rupture is an important cause of death in the acute phase after myocardial infarction (MI). Macrophages play a pivotal role in cardiac remodeling after MI. Apoptosis inhibitor of macrophage (AIM) is secreted specifically by macrophages and contributes to macrophage accumulation …

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Depletion of apoptosis inhibitor of macrophage (AIM) alleviates M1 macrophage recruitment and cardiac repture after myocardial infarction

Shohei Ishikawa, Takahisa Noma, Wataru Takabatake, Yuichi Miyake et autres

Effect of Angiotensin II Receptor Blocker on Cardiac Autonomic Activity in Patients with Chronic Heart Failure

Shohei Ishikawa, Takahisa Noma, Keiji Matsunaga, Kaoru Mantani et autres

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Intracoronary administration of nicorandil during primary percutaneous coronary intervention: Impact on restoration of regional myocardial perfusion in reperfused myocardium during the subacute phase of myocardial infarction

Wataru Takabatake, Takahisa Noma, Yasuyoshi Iwado, Shohei Ishikawa et autres

The impact of nicorandil as adjunctive therapy for percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) is controversial. We performed 15O-labeled water positron emission tomography (PET) to quantify regional myocardial perfusion in patients with STEMI who received nicorandil or …

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A comparison of the University of Wisconsin solution and the modified Kawakami solution for initial flush and coronary perfusion in long-term canine heart preservation.

Hiroyuki Ogiwara, Hideaki Ichikawa, Tohru Takahashi, Akio Ohtaki et autres

BACKGROUND: We compared two different solutions, the University of Wisconsin (UW) solution (intracellular-like) and the modified Kawakami (mK) solution (extracellular-like), for initial flush of coronary vascular beds before simple storage and following coronary perfusion. METHODS: After a right thoracotomy in the 4th …

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[Coronary artery bypass grafting for a patient with left ventricular ejection fraction of 16%: a case report and review of the Japanese literature].

M Aiba, Amane Otaki, Shohei Ishikawa, K. Sakata et autres

A 65-year-old man with left ventricular ejection fraction (LVEF) of 16% successfully underwent coronary artery bypass grafting (CABG). CABG used to be contraindicative for patients with LVEF below 20%. However, such patients are recently involved to indication of CABG if viability of …

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[Smoking habit and cardiovascular diseases].

S Handa, Hiroki Yamazaki, S Ohonishi, Shohei Ishikawa

The relationship between smoking and ischemic heart disease was discussed, in terms of the smoking habit and the mechanisms of acute and chronic effects of smoking on the cardiovascular system as one of the coronary risk factors, with reference to exercise capacity …

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[Techniques for perfusing isolated working rat hearts and ischemic heart model (author's transl)].

Shinichi Mochizuki, Shohei Ishikawa, Hiroaki Ozasa, F Saso et autres