Adam Carter

BHSeP10 Avoiding rectus abdominis muscle harm on fashioning a durable stoma

E. Sams, H Jayamanne, Adam Carter, B. M. Stephenson

Abstract Background Stomas are traditionally constructed through the belly of the rectus abdominis muscle (RAM) but are frequently complicated by parastomal herniation (PSH). Retro-rectus mesh prophylaxis of PSH has not proved useful in their prevention. Methods A novel trephine, the lateral rectus …

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Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial

Chris Parker, Noel W. Clarke, Adrian Cook, Howard Kynaston et autres

BACKGROUND: Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear. METHODS: RADICALS-HD was …

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Identifying infection in chronic wounds in a community setting: A systematic review of diagnostic test accuracy studies

George Edwards, Adam Carter, Chloe Wallis, Gail Hayward et autres

AIM: To determine the diagnostic accuracy of different methods currently available to identify infection in chronic wounds applicable to adult patients in a community setting. DESIGN: Systematic review of diagnostic test accuracy studies. REVIEW METHODS: Two authors independently completed screening, data extraction …

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Complex Metabolism of the Novel Neurosteroid, Ganaxolone, in Humans: A Unique Challenge for Metabolites in Safety Testing Assessment

William L. Fitch, Steven M. Smith, Michael S. Saporito, Gregory D. Busse et autres

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What is the Diagnostic Accuracy of Novel Urine Biomarkers for Urinary Tract Infection?

George Edwards, Anna Seeley, Adam Carter, Maia Patrick Smith et autres

Background: Urinary tract infection (UTI) affects half of women at least once in their lifetime. Current diagnosis involves urinary dipstick and urine culture, yet both methods have modest diagnostic accuracy, and cannot support decision-making in patient populations with high prevalence of asymptomatic …

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Factors Associated with Occurrence and Severity of Acute Kidney Injury in Patients with Sepsis – a Retrospective Database Study

Adam Carter, Milo Engoren

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Enhancing the inpatient ward learning environment: A practical guide

Adam Carter, Albert Gifford, Amy Victoria Lyons, Joseph Sebastian Milton et autres

Inpatient ward placements are rich with practical learning opportunities for medical students; however, many such opportunities go overlooked and underused. Newly qualified doctors often feel underprepared for work on wards; improving student experience on ward placements can address this. Although this requires …

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To What Extent Does Clinically Assisted Nutrition and Hydration Have a Role in the Care of Dying People?

Adam Carter

The question over whether to administer clinically assisted nutrition and hydration (CANH) to a dying patient is controversial, with much debate concerning this sensitive issue. The administration of CANH poses clinical and ethical dilemmas, with supporting and opposing views. Proposed positive effects …

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Rapidly Enlarging Malignant Proliferating Trichilemmal Tumor in a Young Female

Allison Weiffenbach, Kimberly L. Katz, Katherine Rupley, Adam Carter et autres

Malignant proliferating trichilemmal tumors are rare adnexal neoplasms that most commonly occur on the scalp in elderly women. These tumors are associated with recurrence and even nodal or distant metastatic spread. Here we describe a 38-year-old patient who presented with a scalp …

MP04-08 WHY INVESTIGATE ASYMPTOMATIC MICROHEMATURIA? IMPLICATIONS OF APPLYING UK NATIONAL GUIDANCE

Adam Cox, Matthew Jefferies, Mohamad Kamarizan, Maureen Hunter et autres

data set-1:previously reported in IHC of DSC2), which included 39 cases of pure UC and 18 cases of UC with SD.Next, we confirmed the result in the other data set of 77 cases of muscle invasive bladder cancer treated with cystectomy from …

Spine calcium signaling

Adam Carter, Bernardo L. Sabatini

Spines are specialized cellular compartments found at high density on the dendrites of many neurons. Glutamatergic synapses are made onto spines, which house much of the machinery needed to read out synaptic activity. By providing a diffusionally isolated signaling compartment, spines allow …

Practice Problems in Biomedical Organic Chemistry: Self-Guided Problems and Answers for Students in Bioorganic and Organic Chemistry

Adam Carter, Tiffany F. Culver, Robert H. Cichewicz

If you have ideas for topics to be included in future volumes or have suggestion or corrections you would like to share, you can email the authors at rhcichewicz@ou.edu.

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