Xiangri Li

Comprehensive Volatile Metabolite Profiling and Bioactive Marker Discovery of Saposhnikoviae Radix via HS-GC-MS/MS Integrated with Chemometrics and Network Pharmacology

Fangliang He, Xianrui Wang, Jiating Zhang, Lizhi Wan et autres

Background: Saposhnikoviae radix (SR), a valuable Chinese medicinal plant with high medicinal and edible value, suffers from inconsistent quality caused by growth patterns, cultivation duration, and geographical origin. Methods: In this study, comprehensive volatile metabolite profiling using HS-GC-MS/MS combined with multivariate chemometrics …

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Paridis rhizoma total saponins ameliorate abnormal uterine bleeding via regulating Proteus mirabilis 2024-mediated estrogen metabolism in the gut-reproductive axis

Hongmin Ren, Chongjun Zhao, Qiqi Fan, Xuxing Wang et autres

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Multi-Dimensional Mechanisms and Druggability Optimization Strategies of Active Ingredients from Traditional Chinese Medicine in the Treatment of Ulcerative Colitis

Qiqi Fan, Xuxing Wang, Haitao Zhang, Zehua Chang et autres

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by a complex etiology and a protracted disease course. Active ingredients from traditional Chinese medicine (TCM), by leveraging the holistic regulatory advantages of anti-inflammatory activity, immune barrier preservation, and gut microbiota regulation, …

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Comprehensive Analysis of Sinomenii caulis and Menispermi rhizoma Based on Ultra‐High Performance Liquid Chromatography and Ultra‐High Performance Liquid Chromatography‐Quadrupole Time‐of‐Flight‐Mass Spectrometry

Ye Tao, Xinyue Zhang, Wen J. Li, Zirong Wu et autres

ABSTRACT Sinomenii caulis (SC) and Menispermi rhizoma (MR) are Chinese herbal medicines from the same family and are often confused. To achieve identification of SC and MR, the paper used the differential chemical components and the combination characteristics of chemical components to …

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Evodiamine relieves ulcerative colitis through reinventing the communication of "host-gut microbiota-macrophages"

Qiqi Fan, Haili Huang, Hongmin Ren, Yiqi Liu et autres

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Development of TaqMan Real-Time Fluorescent Quantitative PCR Method for Identification and Quantification of Sinomenium acutum-Originated Herbal Drugs

Tao Ye, Kunzi Yu, Xian‐Long Cheng, Xiangri Li et autres

Due to morphological similarities, adulterants are frequently substituted for Qingfengteng (QFT, Sinomenium acutum) in regional markets. This study developed a TaqMan probe-based real-time quantitative polymerase chain reaction (qPCR) assay targeting a 57-base pair (bp) fragment of the internal transcribed spacer 2 (ITS2) …

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The Difference of Chemical Components and Biological Activities of the Raw Products slices and the Wine Steam-Processed Product from Cistanche deserticola

Ying Zhang, Yuewu Wang, Yunfeng Xiao, Haibin Guan et autres

As a well-known Chinese herb medicine, the Cistanche deserticola has been used for the treatment of kidney deficiency syndrome in China for thousands of years. Both the raw product of Cistanche deserticola slices (RCD) and its Wine Steam-Processed Product (WSCD) are used …

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Identification and Analysis of Amygdalin, Neoamygdalin and Amygdalin Amide in Different Processed Bitter Almonds by HPLC-ESI-MS/MS and HPLC-DAD

Shuya Xu, Xinfang Xu, Yuan ShaoXiong, Huan Liu et autres

Processing is a traditional pharmacy technology based on traditional Chinese medicine theory. The traditional Chinese medicine (TCM) ingredients should be processed before being used as a medicine. Processed bitter almonds are widely used in the clinic in TCM for the treatment of …

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Study on determination method of monosaccharide composition and content of polysaccharide in snakegourd peel.

Bian Hao, Yuan ShaoXiong, Pan LiLi, Yang Song et autres

The monosaccharide composition of polysaccharides of different cultivars of Trichosanthes Pericarpium

Bian Hao, Pan LiLi, Shaoxiong Yuan, Xiangri Li

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Remote substituent effects on gas‐phase homolytic Fe–O and Fe–S bond energies of p‐G‐C6H4OFe(CO)2(η5‐C5H5) and p‐G‐C6H4SFe(CO)2(η5‐C5H5) studied using Hartree–Fock and density functional theory methods

Qing Zeng, Zucheng Li, Ling Dong, Daxiong Han et autres

Metal–ligand bond enthalpy data can afford invaluable insights into important reaction patterns in organometallic chemistry and catalysis. In this paper, the Fe–O and Fe–S homolytic bond dissociation energies [ΔHhomo(Fe–O)'s and ΔHhomo(Fe–S)'s] of two series of para‐substituted phenoxydicarbonyl(η5‐cyclopentadienyl) iron [p‐G‐C6H4OFp (1)] and (para‐substituted …

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Comparation of Content Determination of Polysaccharides in Cuscuta Australis and Its Processed Products

Xiangri Li

Objective:To determine content of polysaccharides of different processing drugs(plain-frying drugs,stir-heating drugs with wine and stir-heating drugs with salt) in Cuscuta australis.To explore the processing principle from the angel of changes of polysaccharides.Method:The conversion coefficient of C.australiss polysaccharides to mannitose was obtained by …

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