Jiaoni Chi

Artemisia pollen-induced allergic rhinitis in mice: multi-omics dissection of local and systemic molecular alterations

Jiaoni Chi, Le Chen, Yuxuan Jin, Jin-Lyu Sun et autres

Background Mugwort ( Artemisia vulgaris ) is a predominant aeroallergen for allergic rhinitis (AR) in northern China. However, the molecular changes linking local nasal mucosal inflammation with systemic alterations remain incompletely understood. This study aimed to explore the cross-level regulatory network in …

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Recombinant Art v4.01 protein produces immunological tolerance by subcutaneous immunotherapy in a wormwood pollen-driven allergic asthma female mouse model

Tao Wang, Jiaoni Chi, Zhimin Li, Yue Zhang et autres

Art v4.01 is a well-known profilin protein belonging to the pan-allergens group and is commonly involved in triggering allergic asthma, polyallergy, and cross-sensitization. It is also referred to as Wormwood due to its origin. Crude wormwood extracts are applied for allergen-specific immunotherapy …

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Combination of total glucosides of paeony, narrow‐band ultraviolet B, and oral corticosteroid mini‐pulse therapy for nonsegmental vitiligo: A retrospective study

Jiangwen Gui, Zhimin Li, Bin Zhou, Qiang Li et autres

BACKGROUND: The total glucoside of paeony (TGP) is recognized for its immunomodulatory properties and anti-inflammatory effects. This study evaluates the efficacy of TGP combined with oral mini-pulse therapy (OMP) and narrow-band ultraviolet B (NB-UVB) in treating active nonsegmental vitiligo (NSV). MATERIALS AND …

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Author Correction: Based on network pharmacology and bioinformatics to analyze the mechanism of action of Astragalus membranaceus in the treatment of vitiligo and COVID-19

Yaojun Wang, Ming Ding, Jiaoni Chi, Tao Wang et autres

The original version of this Article contained an error in Affiliation 2, which was incorrectly given as ‘The Fifth School of Clinical Medicine, Anhui Medical University, Hefei, 230032 China’. The correct affiliation is listed below:

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Based on network pharmacology and bioinformatics to analyze the mechanism of action of Astragalus membranaceus in the treatment of vitiligo and COVID-19

Yaojun Wang, Ming Ding, Jiaoni Chi, Tao Wang et autres

Coronavirus disease 2019 (COVID-19) is spreading rapidly around the world. However, the treatment of vitiligo combined with COVID-19 has not been reported. Astragalus membranaceus (AM) has a therapeutic effect on patients with vitiligo and COVID-19. This study aims to discover its possible …

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A Retrospective Statistical Analysis of Vitiligo Exacerbation after COVID‐19 Vaccination in China

Tao Wang, Yaojun Wang, Yue Zhang, Jiaoni Chi et autres

At present, COVID‐19 vaccination is an effective method to stop the spread of the epidemic and reduce disease severity and mortality. It has been reported that COVID‐19 vaccine can activate several autoimmune diseases. However, whether it can affect development of vitiligo remains …

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An allergenic plant calmodulin from Artemisia pollen primes human DCs leads to Th2 polarization

Yue Zhang, Wenzhi Hu, Dongbo Chen, Ming Lei Ding et autres

Artemisiapollen is the major cause of seasonal allergic respiratory diseases in the northern hemisphere. About 28.57% ofArtemisiaallergic patients’ IgE can recognize ArtCaM, a novel allergenic calmodulin fromArtemisiaidentified in this study. These patients exhibited stronger allergic reactions and a longer duration of allergic …

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Letter to the Editor regarding “Monkeypox emerges on a global scale: A historical review and dermatological primer”

Yaojun Wang, Jiaoni Chi, Qiang Li

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Vitiligo as a potential degenerative disease: from oxidative stress to cellular senescence

Yaojun Wang, Jiaoni Chi, Tao Wang, Yue Zhang et autres

Vitiligo is a depigmentation disorder characterized by the loss of melanocytes in the skin, which is aggravated by oxidative stress. The relationship between oxidative stress and cellular senescence is still unclear despite considerable research on melanocyte senescence in vitiligo in recent years. …

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The Formation of Melanocyte Apoptotic Bodies in Vitiligo and the Relocation of Vitiligo Autoantigens under Oxidative Stress

Jun Tian, Yaojun Wang, Ming Ruo Ding, Yue Zhang et autres

Background. Oxidative stress has a vital role in the early stages of vitiligo. Autoantigens released from apoptotic melanocytes (MC) under oxidative stress are involved in the presentation and recognition of antigens. However, the transport of autoantigens to the cell surface and their …

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