Yurui Zhu

A peptide-based nano-PROTAC synergistically driving ferroptosis-immunotherapy in triple-negative breast cancer

Jiasha Wu, Rui Ji, Luyi Wang, Yurui Zhu et autres

Ferroptosis, an emerging mechanism of cell death, provides new targets for the treatment of triple-negative breast cancer (TNBC). Glutathione peroxidase 4 (GPX4), a key regulator of ferroptosis, is a promising therapeutic target for TNBC. Given that GPX4 is often considered “undruggable”, proteolysis …

cn (code pays fourni par la source)

Benchmarking Large Language Models on Reference Extraction and Parsing in the Social Sciences and Humanities

Yurui Zhu, Giovanni Colavizza, Matteo Romanello

Bibliographic reference extraction and parsing are foundational for citation indexing, linking, and downstream scholarly knowledge-graph construction. However, most established evaluations focus on clean, English, end-of-document bibliographies, and therefore underrepresent the Social Sciences and Humanities (SSH), where citations are frequently multilingual, embedded in …

Benchmarking Large Language Models on Reference Extraction and Parsing in the Social Sciences and Humanities

Yurui Zhu, Giovanni Colavizza, Matteo Romanello

Bibliographic reference extraction and parsing are foundational for citation indexing, linking, and downstream scholarly knowledge-graph construction. However, most established evaluations focus on clean, English, end-of-document bibliographies, and therefore underrepresent the Social Sciences and Humanities (SSH), where citations are frequently multilingual, embedded in …

Dual-Stimuli-Responsive Nanoplatform Delivering Molecular Glue CR8 for Synergistic CDK12 Degradation and Immunomodulatory Photothermal Therapy in TNBC

Nan Zhang, Huaxing Shen, Wei Cong, Yurui Zhu et autres

The clinical translation of the molecular glue CR8, a potent CDK12/CCNK degrader for reversing TNBC immunosuppression, is severely hampered by its poor solubility and off-target toxicity. To surmount these challenges, we engineered an intelligent nanoplatform, ZCPc, for synergistic chemo-photothermal-immunotherapy. Leveraging the intrinsic …

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Spatiotemporally controlled protein degradation via NIR-activatable PROTAC platform

Nan Wang, Wei Cong, Yurui Zhu, Huaxing Shen et autres

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VisionSelector: End-to-End Learnable Visual Token Compression for Efficient Multimodal LLMs

Yurui Zhu, Xin Biao Lu, Wenrui Yan, Dong Li et autres

Multimodal Large Language Models (MLLMs) encounter significant computational and memory bottlenecks from the massive number of visual tokens generated by high-resolution images or multi-image inputs. Previous token compression techniques are often constrained by heuristic rules that risk discarding critical information. They may …

DDCNet: Advanced Decoupling of Degradation and Content for Adverse Weather Image Restoration

X. L. Wang, Xueyang Fu, Yurui Zhu, Zheng-Jun Zha

Adverse weather image restoration aims to recover clear images from those affected by weather conditions such as rain, haze, and snow. Different weather types affect images in distinct ways, necessitating specific degradation removal strategies, while content reconstruction generally benefits from a consistent …

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Continuous Adverse Weather Removal via Degradation-Aware Distillation

Xin Lu, Jie Xiao, Yurui Zhu, Xueyang Fu

All-in-one models for adverse weather removal aim to process various degraded images using a single set of parameters, making them ideal for real-world scenarios. However, they encounter two main challenges: catastrophic forgetting and limited degradation awareness. The former causes the model to …

Encoder-Enhanced Graph Convolutional Network for Cross-Domain Mechanical Fault Diagnosis

Yurui Zhu, Xin Ma, Jinglin Zhou, Dazi Li

Graph Convolutional Network (GCN) has been widely applied in mechanical fault diagnosis due to its ability to extract features from data in non-Euclidean spaces. However, the local aggregation mechanism in GCN has difficulty capturing the dynamic propagation relationships between fault signals. Additionally, …

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GepA, a GGDEF-EAL protein, regulates biofilm formation and swimming motility in Vibrio parahaemolyticus

Miaomiao Zhang, Yurui Zhu, Xue Li, Xi Luo et autres

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A novel label-aware global graph construction method and spiking-coded graph neural network for intelligent process fault diagnosis

Dazi Li, Yurui Zhu, Zhihuan Song, Hamid Reza Karimi

cn, it (code pays fourni par la source)

SDCNet:Spatially-Adaptive Deformable Convolution Networks for HR NonHomogeneous Dehazing

Yidi Liu, Xingbo Wang, Yurui Zhu, Xueyang Fu et autres

In recent years, the field of image dehazing has garnered increasing attention. Many deep learning models have demonstrated exceptional capabilities in removing homogeneous haze, yet they often perform suboptimally when faced with the challenge of non-homogeneous dehazing. One of the primary issues …

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