Feng Ye

Prediction of Early Recurrence After Bronchial Arterial Chemoembolization in Non-small Cell Lung Cancer Patients Using Dual-energy CT: An Interpretable Model Based on SHAP Methodology

Feng Ye, Yu Xu, Jian Wang, Zhenyu Cao et autres

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A Rare Case of Hyperamylasemia With a Rare Cause

Yuwen Tao, Wenfang Chen, Feng Ye

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Cell-selective telomere damage by thiopurine-based oligonucleotide for diffuse large B cell lymphoma immunotherapy

Chunsong Yu, Elaine Kang, Dongfang Wang, Yong Liang et autres

Telomerase (TERT) is an enzyme involved in maintaining telomere length in diffuse large B cell lymphoma (DLBCL). Previous attempts to target TERT + cancers faced challenges, including the delayed clinical responses and on-target/off-tumor toxicities. Here, we present a DLBCL-targeted oligonucleotide designed to …

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Value of intratumoral combined with peritumoral radiomics model in the prediction of Ki-67 expression in lung adenocarcinoma: a multi-center study

Feng Ye, Bojun Liu, Chenchen Hong, Linqiang Lai et autres

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Non-foreign body-associated risk factors for complications associated with esophageal foreign-body removal and timing of endoscopic treatment: a single-center retrospective study

Zhiqing He, Qing Xu, Wentao Fan, Jinjin Shi et autres

BACKGROUND: Complications from prolonged esophageal foreign body impaction are well-documented, yet the significance of non-foreign body factors has not been thoroughly explored. This study aims to investigate non-foreign body risk factors for complications during esophageal foreign-body removal and to evaluate the impact …

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Survival benefits of propofol-based versus inhalational anesthesia in non-metastatic breast cancer patients: a comprehensive meta-analysis

Ying–Jun Angela Zhang, Ping Yu, Lei Bian, Wanwei Huang et autres

Whether the anesthesia technique, inhalational general anesthesia (IGA) or propofol-based anesthesia (PBA), influences the long-term survival of non-metastatic breast cancer (eBC) remain unclear and controversial. We carried out a literature search on 16thJuly, 2022 for studies comparing IGA and PBA in eBC …

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A multicentre, randomised, double-blind, double-dummy, parallel-controlled, phase 3 clinical trial assessing the efficacy and safety of intravenous nemonoxacin malate vs. levofloxacin for community-acquired pneumonia in adult patients

Ying Li, Demei Zhu, Shenghua Sun, Xiaoyue Chang et autres

BACKGROUND: Nemonoxacin malate is a novel non-fluorinated quinolone for oral and intravenous (IV) administration. This phase 3, multicentre, randomised, double-blind, double-dummy, parallel-controlled clinical trial (NCT02205112) evaluated the efficacy and safety of IV nemonoxacin vs. levofloxacin for the treatment of community-acquired pneumonia (CAP) …

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Crizotinib inhibits the metabolism of tramadol by non-competitive suppressing the activities of CYP2D1 and CYP3A2

Nanyong Gao, Xiaoyu Xu, Feng Ye, Xinyue Li et autres

Objectives: To investigate the interaction between tramadol and representative tyrosine kinase inhibitors, and to study the inhibition mode of drug-interaction. Methods: Liver microsomal catalyzing assay was developed. Sprague-Dawley rats were administrated tramadol with or without selected tyrosine kinase inhibitors. Samples were prepared …

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A combination of cuproptosis and lncRNAs predicts the prognosis and tumor immune microenvironment in cervical cancer

Yitong Huang, Chenxiang Pan, Suni Wu, Feng Ye et autres

BACKGROUND: Cuproptosis induces proteotoxic stress and eventually leads to cell death. However, the relationship between cuproptosis and lncRNAs in cervical cancer has not been fully elucidated. Therefore, we aim to explore the association among lncRNAs, cuproptosis and clinical features in cervical cancer. …

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Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study

Baohong Jiang, Na Li, Wei Du, Lijun Zeng et autres

BACKGROUND: Ganoderma lucidum extracts are widely used as adjuvants in the treatment of triple-negative breast cancers (TNBC) in China. However, its clinical value in TNBC remains unclear. Therefore, we investigated the clinical effect of Ganoderma lucidum spore powder (GLSP) on prognosis in …

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Immune checkpoint inhibitor myocarditis in thymic epithelial tumors: a case report and literature review

Feng Ye, Peng Zheng, Wei Zhang, Sheng Yang et autres

Background: Immunotherapy offers new hope for cancer patients but presents new medical challenges for healthcare workers in terms of the management of immune-related adverse events (irAEs). The clinical data of two patients with advanced thymoma (T) admitted to the Fujian Cancer Hospital …

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Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer

Feng Ye, Saikat Dewanjee, Yuehua Li, Niraj Kumar Jha et autres

Breast cancer is the second leading cause of death for women worldwide. The heterogeneity of this disease presents a big challenge in its therapeutic management. However, recent advances in molecular biology and immunology enable to develop highly targeted therapies for many forms …

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