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Profil bibliographique

Swagatika Dash

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

37Publications signalées
571Citations signalées
4Affiliations récentes

Les institutions déclarées

Les domaines associés

Marine Biology and Environmental ChemistryExtraction and Separation ProcessesMarine Sponges and Natural ProductsMicrobial Community Ecology and PhysiologyMarine Ecology and Invasive Species

Les publications récentes

Accès ouvert 2026 preprint OpenAlex

Low levels of metabolic auxotrophy among environmental Pseudomonas isolates

Simon Maréchal, Benjamin Heiniger, Shaohua Gu, Swagatika Dash et autres

Abstract Auxotrophy, the inability of bacteria to synthesize one or multiple essential metabolites (e.g. amino acids, vitamins, metabolites) is thought to be common among bacteria. However, studies often rely either on bioinformatic tools to predict auxotrophies from genome data or on experiments …

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0 citations bioRxiv (Cold Spring Harbor Laboratory)
2025 article OpenAlex

In Silico Exploration of Cordia Macleodii Derived Theaflavin as a Novel mTOR Inhibitor for Cancer Therapy

Sangeeta Adile, Ashutosh Gupta, Swagatika Dash, Rohit Seth

Abstract Theaflavin, a key polyphenolic compound, exhibits potent antioxidant, anti‐inflammatory, and anticancer activities. It neutralizes oxidative stress, inhibits pro‐inflammatory pathways, and targets oncogenic signaling molecules such as Bcl‐2, NF‐κB, and mTOR, leading to apoptosis and cell cycle arrest in cancer cells. Beyond …

in (code pays fourni par la source)

1 citation ChemistrySelect
Accès ouvert 2024 article OpenAlex

Genetic Characterization of Plasmodium falciparum Histidine-Rich Protein 2 Deletions and Their Impact on Malaria Interventions in Odisha, India

Stuti Mohanty, Abbey M. Jones, Swagatika Dash, Satya Ranjan Chhatria et autres

Diagnostic escape via Plasmodium falciparum (P. falciparum) histidine-rich protein 2 (pfhrp2) gene deletions is a major potential hurdle for global malaria elimination efforts. We investigated the prevalence of pfhrp2 gene deletions in 15 malaria-endemic villages in the state of Odisha, India, and …

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2 citations American Journal of Tropical Medicine and Hygiene
Accès ouvert 2024 article OpenAlex

Immunoinformatics design of a multi-epitope vaccine for Chlamydia trachomatis major outer membrane proteins

Seema Shetty, Swagatika Dash, Shashidhar Vishwanath, Suvarna G. Kini et autres

Chlamydia trachomatis (CT) remains a significant infectious cause of blindness and sexually transmitted infections worldwide. The objective and novelty of this study lie in using different serovars of CT to design a broad-spectrum multi-epitope vaccine that might confer immunity against different CT …

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8 citations Scientific Reports
Accès ouvert 2024 article OpenAlex

Identification of DprE1 inhibitors for tuberculosis through integrated in-silico approaches

Swagatika Dash, Ekta Rathi, Kiran Chawla, Suvarna G. Kini

Abstract Decaprenylphosphoryl-β-D-ribose-2′-epimerase (DprE1), a crucial enzyme in the process of arabinogalactan and lipoarabinomannan biosynthesis, has become the target of choice for anti-TB drug discovery in the recent past. The current study aims to find the potential DprE1 inhibitors through in-silico approaches. Here, …

in (code pays fourni par la source)

24 citations Scientific Reports
2024 article OpenAlex

RP HPLC Enabled Novel Analytical Method for the Development and Quantification of Cefuroxime Axetil in its Bulk Drug and Pharmaceutical Formulations

Haragouri Mishra, Amulyaratna Behera, Sidhartha Shankar Kar, Swagatika Dash

Abstract Current investigations aim to develop and validate an accurate, simple, specific, and precise RP‐HPLC method for the detection of cefuroxime axetil, in bulk and tablet dosage forms. Despite extensive literature reviews, no method could be found for estimating the variables mentioned …

in (code pays fourni par la source)

0 citations Macromolecular Symposia
2023 article OpenAlex

Structure-activity relationship mediated molecular insights of DprE1 inhibitors: A Comprehensive Review

Swagatika Dash, Ekta Rathi, Avinash Kumar, Kiran Chawla et autres

Emerging threats of multi-drug resistant (MDR), extensively drug-resistant (XDR), and totally drug-resistant (TDR) tuberculosis led to the discovery of a novel target which was entitled Decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) enzyme. DprE1 is composed of two isoforms, decaprenylphosphoryl-β-D-ribose oxidase (DprE1) and decaprenylphosphoryl-D-2-keto erythro pentose …

in (code pays fourni par la source)

10 citations Journal of Biomolecular Structure and Dynamics

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