Keng‐Liang Wu

Alternation of the oral, gastric and stool microbiome in patients with reflux esophagitis and Barrett's esophagus

Chih‐Chien Yao, Wei-Chen Tai, Chih-Ming Liang, Ming‐Chao Tsai et autres

BACKGROUND: The imbalance of human microbiota has been associated with various inflammatory disease. Compared to intestinal flora, the esophageal microbiome has been understudied,and it remains unclear whether dysbiosis is related to reflux esophagitis (RE) and Barrett's esophagus (BE).This study aimed to synthesize …

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Fan-out RDL process and shuttle service

Chen-Chun Yu, Yi-Shu Chen, Yuan‐Chang Lee, Huan‐Chun Fu et autres

With the rapid advancement of artificial intelligence (AI) technologies, AI chips have emerged as a cornerstone in enabling high-performance and data-intensive applications. A wide spectrum of related products is actively exploring approaches to integrate AI functionality. A defining characteristic of such innovative …

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Fan-out RDL Packaging Process and Shuttle Service

Chen-Chun Yu, Hsiang‐Hung Chang, Yi-Shu Chen, Yuan‐Chang Lee et autres

With the rapid development of AI technology, AI chips have become a cornerstone of high-end technological applications. Various related products are actively exploring ways to integrate AI technology. A hallmark of innovative products and startups is their need for diverse, small-batch manufacturing. …

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[Rapid promyelocytic blast crisis of chronic myeloid leukemia with PML-RARα fusion gene: a case report and literature review].

Min Liu, Xiaoyan Han, Zhiguo Qu, Qianyi Luo et autres

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Real-World Evidence of Effectiveness and Safety of Vedolizumab for Inflammatory Bowel Disease in Taiwan: A Prospective Nationwide Registry (VIOLET) Study

Wei‐Chen Lin, Wei‐Chen Tai, Chung‐Hsin Chang, Chia‐Hung Tu et autres

BACKGROUND: This nationwide prospective registry study investigated the real-world effectiveness, safety, and persistence of vedolizumab (VDZ) in inflammatory bowel disease (IBD) patients in Taiwan. Disease relapse rates after VDZ discontinuation due to reimbursement restriction were assessed. METHODS: Data were collected prospectively (January …

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Extremity risk factors of sepsis for gastrointestinal endoscopy in patients with liver cirrhosis

Yi‐Chia Chan, Chao‐Long Chen, Chih‐Chi Wang, Chih‐Che Lin et autres

BACKGROUND: Liver cirrhosis is a well-known risk factor of sepsis after emergent gastrointestinal (GI) endoscopy. Elective GI endoscopy before living donor liver transplantation (LDLT), however, may also carry the septic risk among these patients. METHODS: This retrospective study reviewed the medical records …

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[Safety evaluation of hyperthermic intraperitoneal chemotherapy in patients with local advanced gastric cancer after radical resection for prevention of peritoneal metastasis].

Yecheng Lin, Chao Shen, Xiangling Guo, Y Li et autres

Radical surgery + HIPEC does not significantly increase the incidence of perioperative complications in patients with advanced gastric cancer. The age >60 years and nerve invasion are independent risk factors for adverse events in these patients.

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The effectiveness and safety of vedolizumab induction for moderate to severe ulcerative colitis for Asia patient: A real practice observational study

Chia‐Jung Kuo, Puo‐Hsien Le, Wei‐Chen Tai, Keng‐Liang Wu et autres

BACKGROUND: The use of biologic agents has become the cornerstone of therapy for moderate to severe IBD. Few studies have investigated the efficacy of vedolizumab (VDZ) induction for ulcerative colitis (UC) in Asian patients in a real practice setting. AIMS: To evaluate …

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Autonomic impairment in treatment-naive patients with chronic hepatitis B and C infections

Chih‐Cheng Huang, Keng‐Liang Wu, Jiashou Liu, Yung‐Yee Chang

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Per oral endoscopic myotomy for achalasia: A Taiwanese single‐center experience

Yu‐Chi Lee, Wei‐Chen Tai, Keng‐Liang Wu, Chih‐Chien Yao et autres

Abstract Endoscopic treatment of achalasia includes endoscopic botulinum toxin injection, endoscopic pneumatic dilations (PD) but surgery owns longer durability. Per oral endoscopic myotomy (POEM) carries high expectations with good short and mid‐term report and only minor morbidity in Western and Eastern countries …

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P425 Real-world evidence on effectiveness and safety of vedolizumab therapy for inflammatory bowel disease in Taiwan: Results from the TSIBD registry (VIOLET Study)

Shu‐Chen Wei, Wei‐Chen Lin, Chung‐Hsing Chang, Chia‐Hung Tu et autres

Abstract Background GEMINI trials and real-world studies in Western population have demonstrated the effectiveness and safety of vedolizumab (VDZ) for IBD. However, long-term real-world evidence of VDZ in Asian populations remains limited. This study aimed to investigate the effectiveness and safety of …

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An update on endoscopic treatment for achalasia: From per oral endoscopic myotomy to endolumenal functional lumen imaging probe

Wei‐Chen Tai, Keng‐Liang Wu, Seng‐Kee Chuah

Traditional endoscopic treatment of achalasia includes endoscopic local injection of botulinum toxin into the lower esophageal sphincter (LES) muscle, endoscopic balloon dilations.1, 2 Injection of botulinum toxin is safe and only may be associated with minor complications but the main drawback is …

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