Weizhen Chen

Gut derived (S)-Equol mitigates influenza viral pneumonia by modulating macrophage polarization via Nrf2 mediated AKT/ERK/NF-κb signaling pathways

Zheying Mao, Chang Liu, Joshua Ni, Mingzhu Huang et autres

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Metabolomic profiling of plasma reveals differential disease severity markers in avian influenza A(H7N9) infection patients

Yuefeng Wang, Joshua Ni, Mingzhu Huang, Wenxin Qu et autres

OBJECTIVES: Avian influenza such as H7N9 is currently a major global public health risk, and at present, there is a lack of relevant diagnostic and treatment markers. METHODS: We collected plasma samples from 104 confirmed H7N9 patients, 31 of whom died. Plasma …

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Corrigendum to “Metal-phenolic networks as a promising platform for pH-controlled release of bioactive divalent metal ions” [Appl. Surf. Sci. 511 (2020) 145569]

Kui Xu, Mi Zhou, Ming Li, Weizhen Chen et autres

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Cepharanthine attenuates pulmonary fibrosis via modulating macrophage M2 polarization

Jiaqi Bao, Chang Xin Liu, Huafeng Song, Zheying Mao et autres

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a group of chronic interstitial pulmonary diseases characterized by myofibroblast proliferation and extracellular matrix (ECM) deposition. However, current treatments are not satisfactory. Therefore, more effective therapies need to be explored. Cepharanthine (CEP) is a naturally occurring …

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Remote-sensing extraction and carbon emission reduction benefit assessment for centralized photovoltaic power plants in Agrivoltaic systems

Chenhao Huang, Lijian Xie, Weizhen Chen, Yixuan Wu et autres

The utilization of renewable energy is an essential way to address climate change and achieve “carbon neutrality”. As one of the most promising strategies for energy development, photovoltaic (PV) power generation has gained significant attention. In order to scientifically estimate its ecological …

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Effect of early cannulation with metal needles on arteriovenous fistula patency in patients undergoing hemodialysis

Zuanhong Jiang, Manman Liu, Lingling Zhou, Weizhen Chen et autres

Background: Autogenous arteriovenous fistula (AVF) is the preferred vascular access mode. However, the earliest possible time for AVF puncture and whether premature puncture affects the AVF patency rate remain unclear. Methods: In this multicenter retrospective cohort study, adult uremic patients who underwent …

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ddPCR provides a sensitive test compared with GeneXpert MTB/RIF and mNGS for suspected Mycobacterium tuberculosis infection

Dan Zhang, Fei Yu, Dongsheng Han, Weizhen Chen et autres

Introduction The Metagenomics next-generation sequencing (mNGS) and GeneXpert MTB/RIF assay (Xpert) exhibited a sensitivity for tuberculosis (TB) diagnostic performance. Research that directly compared the clinical performance of ddPCR analysis, mNGS, and Xpert in mycobacterium tuberculosis complex (MTB) infection has not been conducted. …

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Life Cycle-Based Carbon Emission Reduction Benefit Assessment of Centralized Photovoltaic Power Plants in China

Yanhua Deng, Jiji Wu, Qian Yang, Weizhen Chen et autres

Developing clean energy is the key to reducing greenhouse gas (GHG) emissions and addressing global climate change. Photovoltaic energy systems are considered to be clean and sustainable energy resources due to their wide distribution and easy deployment. However, the environment can still …

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Platelet Rich Plasma Loaded Multifunctional Hydrogel Accelerates Diabetic Wound Healing via Regulating the Continuously Abnormal Microenvironments

Kui Xu, Sijie Deng, Yabin Zhu, Wei Yang et autres

Continuous oxidative stress and cellular dysfunction caused by hyperglycemia are distinguishing features of diabetic wounds. It has been a great challenge to develop a smart dressing that can accelerate diabetic wound healing through regulating abnormal microenvironments. In this study, a platelet rich …

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Dynamic associations between the respiratory tract and gut antibiotic resistome of patients with COVID-19 and its prediction power for disease severity

Yifei Shen, Wenxin Qu, Fei Yu, Dan Zhang et autres

The antibiotic resistome is the collection of all antibiotic resistance genes (ARGs) present in an individual. Whether an individual's susceptibility to infection and the eventual severity of coronavirus disease 2019 (COVID-19) is influenced by their respiratory tract antibiotic resistome is unknown. Additionally, …

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Dynamic changes in the respiratory tract and gut antibiotic resistome of patients with COVID-19 and its association with disease severity

Yifei Shen, Wenxin Qu, Fei Yu, Dan Zhang et autres

Abstract Background The antibiotic resistome is the collection of all the antibiotic resistance genes (ARGs) present in an individual. Whether an individual’s susceptibility to infection and the eventual severity of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 …

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Impact of short-term ambient air pollution exposure on the risk of severe COVID-19

Baihuan Feng, Jiangshan Lian, Fei Yu, Dan Zhang et autres

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