2025
conference-paper
OpenAlex
Gideon Hirshfield, Christopher L. Bowlus, D. I. Jones, Andreas Emanuel Kremer et autres
Introduction Cholestatic pruritus is common, debilitating and undertreated in patients with PBC. Here, we describe the results of GLISTEN (NCT04950127), a Phase 3 study investigating efficacy and safety of linerixibat (ileal bile acid transporter inhibitor) for pruritus in PBC. Methods In this …
ca, us, gb, ch, jp, it, cn, mx, es
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2025
conference-paper
OpenAlex
Gideon Morris Hirschfield, Christopher L. Bowlus, D. I. Jones, Andreas Emanuel Kremer et autres
Background and Aims: Cholestatic pruritus is common, debilitating and undertreated in patients with primary biliary cholangitis (PBC). Here, we describe the results of GLISTEN (NCT04950127), a Phase 3 study investigating the efficacy and safety of the ileal bile acid transporter inhibitor linerixibat …
ca, us, gb, ch, jp, it, cn, mx, fi
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Accès ouvert
2020
article
OpenAlex
Peipei An, Lina Feng, Xiaoxue Zhang, Qinglong Jin
BACKGROUND: This study was aimed to evaluate the association between interleukin-6 (IL-6) gene polymorphisms and the risk of hepatocellular carcinoma (HCC) in a meta-analysis. METHODS: A literature search was performed for case-control studies published during May, 1993 to May, 2020 focusing on …
de, cn
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Accès ouvert
2020
article
OpenAlex
Xiaowei Zhong, Siyi Huang, Dianfeng Liu, Ziping Jiang et autres
BACKGROUND: Galangin has been extensively studied as the antitumor agent in various cancers. However, the effect of galangin in hepatocellular carcinoma (HCC) remains elusive. METHODS: Using RNA sequencing, the differential expression of lncRNA in human HCC cell line with highly metastatic potential …
cn
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2013
article
OpenAlex
A Ryun Kim, Qinglong Jin, Hongguang Jin, Hae Ju Ko et autres
kr
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2013
article
OpenAlex
Ji Hong Hwang, Qinglong Jin, Eun‐Rhan Woo, Dong Gun Lee
kr
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2012
article
OpenAlex
Hongguang Jin, Qinglong Jin, A. Ryun Kim, Hyemin Choi et autres
kr
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2012
article
OpenAlex
Qinglong Jin, Hongguang Jin, A Ryun Kim, Eun‐Rhan Woo
Abstract A new megastigmane palmitate, 9‐oxomegastigm‐5(13)‐ene‐2β‐palmitate (1), and a new oleanane triterpenoid, (3β)‐3,23,28‐trihydroxyolean‐12‐en‐11‐one (2), together with three known oleanane‐type triterpenoids, β‐amyrin (3), erythrodiol (4), and (3β)‐olean‐12‐ene‐3,23,28‐triol (5), were isolated from the aerial parts of Aster yomena (Asteraceae). Their structures were identified based …
kr
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2012
article
OpenAlex
Qinglong Jin, HG Jin, Ar Kim, ER Woo
Aster yomena Makino (Asteraceae) is a perennial herb that is distributed throughout Korea and Japan. The whole plant is used in Korean traditional medicine for the treatment of bronchial asthma, inflammation, and cold. In addition, phytochemical and biological studies of this plant …
kr
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Accès ouvert
2012
article
OpenAlex
Jee‐Young Lee, Jin‐Kyoung Kim, So-Jung Lee, Eunjung Lee et autres
Human peroxisome proliferator-activated receptor gamma ( $hPPAR{\gamma}$ ) has been implicated in numerous pathologies, including obesity, diabetes, and cancer. In this study, we verified that amentoflavone is an agonist of $hPPAR{\gamma}$ and probed the molecular basis of its action. It was demonstrated …
kr
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Accès ouvert
2012
article
OpenAlex
Hyemin Choi, Jae‐Yong Cho, Qinglong Jin, Eun‐Rhan Woo et autres
kr
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2011
article
OpenAlex
Qinglong Jin, Hongguang Jin, Jieun Shin, Jongki Hong et autres
Abstract The new phenylethanoid glycosides, purpureaside D (Ia) and purpureaside E (Ib), are isolated together with two known phenylethanoid glycosides.
kr
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