Tae Young Han

Downregulation of intraepidermal nerve fiber densities in psoriasis

Dai Hyun Kim, Jiyun Lim, Yu Jin Lee, Tae Young Han et autres

kr (code pays fourni par la source)

A multiple ascending dose, phase1b study to evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of lesigercept, a long-acting IgETrap-Fc fusion protein, in participants with atopy or allergic diseases

You Sook Cho, Young Min Ye, Sook Young Lee, Sae‐Hoon Kim et autres

Background Lesigercept (also known as YH35324) has shown favorable safety, dose-proportional pharmacokinetics (PK), and sustained suppression of serum free immunoglobulin E (IgE) after single dosing in participants with atopy. We examined these outcomes following repeated dosing in participants with atopy or allergic …

kr, jp (code pays fourni par la source)

SFPQ/S100A8 complex induces filaggrin deficiency via selective autophagy and JNK phosphorylation in atopic dermatitis

Geunyeong Kim, Yujin Hong, Tae Young Han, Byeol Han et autres

Although atopic dermatitis (AD) is associated with a decrease of filaggrin levels, the underlying mechanisms are not clearly understood. Here, we aimed to investigate the pathogenic roles of the splicing factor proline- and glutamine-rich (SFPQ)/S100 calcium-binding protein A8 (S100A8) complex, a critical …

kr (code pays fourni par la source)

Role of CRM1-mediated SFPQ/S100A8 complex formation in psoriasis

Geunyeong Kim, Yujin Hong, Ji-Sook Lee, Juram Lee et autres

kr (code pays fourni par la source)

Efficacy and Safety of Alitretinoin for Chronic Hand Eczema: A Meta-Analysis

Yu Jin Lee, Jung Min Lee, Yun Jeong Choi, Tae Young Han et autres

BACKGROUND: Hand eczema is a common inflammatory dermatosis that can severely impair quality of life. Chronic or refractory cases often require systemic therapy. Alitretinoin, a vitamin A derivative, is approved for patients unresponsive to potent topical corticosteroids. OBJECTIVE: This meta-analysis aimed to …

kr (code pays fourni par la source)

Development of the Definition, Diagnostic Criteria, Clinical Subtypes, and Severity Assessment Tools for Prurigo Nodularis in Korea Based on Expert Consensus Surveys

Youin Bae, Jihee Kim, Tae Young Han, Ji Hyun Lee et autres

Background: Prurigo nodularis (PN) is a chronic pruritic dermatosis characterized by multiple hyperkeratotic nodules with severe itch.Although international expert groups have proposed standardized diagnostic frameworks for chronic prurigo, such standards have not been established in Korea.Objective: To develop expert consensus on terminology, …

kr (code pays fourni par la source)

When Eosinophilic Granulomatosis With Polyangiitis (EGPA) Goes Large: A Rare Presentation of EGPA With Isolated Aortitis

S. Jahnz, D. Lamorte, Tae Young Han

Abstract Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is a vasculitis characterized by asthma, chronic rhinosinusitis, neuropathies, pulmonary infiltrates, and eosinophilia. It most commonly affects small and medium vessels. Presented here is a patient with clinical features typical of EGPA but with isolated …

us (code pays fourni par la source)

Real-World Prevalence and Associated Factors of Nipple Eczema in Patients With Atopic Dermatitis

Jung Min Lee, Yu Jin Lee, June Hyunkyung Lee, Jae Eun Choi et autres

Background: Nipple eczema (NE) manifests as pruritic or painful erythema, often accompanied by oozing, erosion, and lichenification.NE is observed in 6%-23% of patients with atopic dermatitis (AD); its prevalence is higher among adolescent and young adult women.Objective: To determine the prevalence and …

kr (code pays fourni par la source)

Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): Basic Therapy, Topical Therapy, and Conventional Systemic Therapy

Hyun‐Chang Ko, Yu Ri Woo, Joo Yeon Ko, Hye One Kim et autres

BACKGROUND: Atopic dermatitis (AD) is a common skin disease with a wide range of symptoms. Due to the rapidly changing treatment landscape, regular updates to clinical guidelines are needed. OBJECTIVE: This study aimed to update the guidelines for the treatment of AD …

kr (code pays fourni par la source)

Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part II): Biologics and JAK inhibitors

Hyun‐Chang Ko, Yu Ri Woo, Joo Yeon Ko, Hye One Kim et autres

BACKGROUND: Atopic dermatitis (AD) is a common skin disease with a wide range of symptoms. Due to the rapidly changing treatment landscape, regular updates to clinical guidelines are needed. OBJECTIVE: This study aimed to update the guidelines for the treatment of AD …

kr (code pays fourni par la source)

Management of pirfenidone-induced skin photosensitivity with upadacitinib

Yu Jin Lee, Jung Min Lee, June Hyunkyung Lee, Tae Young Han et autres

Dear Editor, A 76-year-old man presented with severely pruritic eczematous lesions characterized by lichenification over his entire body, primarily affecting sun-exposed areas such as his face, nape, and forearms, and exhibiting a sharply demarcated outlines. These lesions had initially manifested as scalp …

kr (code pays fourni par la source)

2023 Consensus Korean Diagnostic Criteria for Atopic Dermatitis

Ji Hyun Lee, Sul Hee Lee, Youin Bae, Young Bok Lee et autres

BACKGROUND: In 2006, the Korean Atopic Dermatitis Association (KADA) working group released the diagnostic criteria for Korean atopic dermatitis (AD). Recently, more simplified, and practical AD diagnostic criteria have been proposed. OBJECTIVE: Based on updated criteria and experience, we studied to develop …

kr, Nigéria (code pays fourni par la source)