Yang Ding

Disruption of mitochondrial metabolism in systemic lupus erythematosus: multi-omics insights from a patient-derived cohort

Minmin Wu, Qinxin Zhang, Haomiao Wang, Donge Tang et autres

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by dysregulated immune responses and metabolic disturbances. Growing evidence implicates mitochondrial dysfunction in the pathogenesis of SLE; however, a comprehensive multi-omics analysis of mitochondrial pathways has been lacking. Here, we originally performed …

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A Dataset of Node Centrality and Structural Hole Indicators in China’s Chip Technology Innovation Cooperation Network (2009–2023)

Wei Qifeng, Yang Ding

This dataset serves as supplementary data for the paper Characteristics and Evolution of China’s Chip Technology Innovation Collaboration Network, primarily supporting the content in Section 2.3 Analysis of Individual Network Nodes. Due to length constraints, the main text only presents nodes ranking …

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L-kynurenine reshapes immune microenvironment to alleviate methamphetamine-induced chronic lung injury through gut-lung axis

Pei-Jun Ma, Ming Li, Weiting Hu, Yang Ding et autres

Long-term abuse of methamphetamine (MA) is strongly associated with severe lung injury. Microbiome metabolites are one way to understand the interactions between microbes and disease. Although gut microbes and their metabolites play a crucial role in the gut–lung axis, the microbial mechanism …

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S100A9 deficiency mitigates cardiac oxidative stress and improves function via SIRT3 in HFpEF mice

Jiang Yu, Xiaorong Li, Fang He, Zhe Cheng et autres

Heart failure with preserved ejection fraction (HFpEF) is the predominant manifestation of heart failure, yet effective treatment options remain limited, and its underlying mechanisms are not well understood. In the present study, the hearts of HFpEF mice were collected for proteomics analyses, …

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Comparison of safety, salivary flow rate, and pH with different mouthrinse formulations in addition to toothbrushing vs toothbrushing only

Kimberly R Milleman, Mary Lynn Bosma, Atsushi Saito, Patricia C Gorecki et autres

BACKGROUND: Some mouthrinse ingredients are perceived as being associated with a reduction in salivary flow, leading to dry mouth. In this trial, the authors evaluated the effect of essential oil (EO)-containing mouthrinses, with or without alcohol, in addition to toothbrushing on oral …

Positive relative accommodation is an independent risk factor for myopia onset: a prospective cohort study among chinese primary schoolchildren, the WEPrOM study

Yingying Ye, Yimin Yuan, Chengnan Guo, Yingying Huang et autres

PURPOSE: To identify independent risk factors for myopia onset in schoolchildren, with a focus on binocular visual function. METHODS: We conducted a school-based prospective cohort study in Wenzhou, China. Schoolchildren in grades 2 and 3 were recruited in 2014 and followed until …

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The application of objective structured clinical examinations for evaluating clinical internship in long-term clinical medical students in China

Miao Yang, Yao Liu, Yuhan Dong, Yang Ding et autres

Background Clinical internship plays a vital role in enhancing medical students’ theoretical knowledge, clinical operational abilities, and clinical thinking development. This study aims to establish an efficient evaluation system to assess interns’ proficiency in clinical skills, and analyze the teaching effectiveness of …

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Identification of GBP6 as a potential prognostic biomarker in esophageal carcinoma by integrated bioinformatics analysis and experiment validation

Shilin Fang, Yang Ding, Yifan Jia, Liping Gao et autres

BACKGROUNDS: To evaluate the role of guanylate-binding protein 6 (GBP6) in esophageal cancer (ESCA). METHODS: We comprehensively evaluated the expression pattern, clinical features, prognostic role, biological functions, and immunological role of GBP6 based on the public databases. Immunohistochemistry was used to validate …

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Research Progress on Psychological Stress of Nursing Students During Internship

Dan Wang, He Xu, Tingting Wang, Yang Ding

This study aims to explore the psychological stress faced by nursing students during their internships and its relationship with self-efficacy and mental health. Through a literature review and survey analysis, it was found that nursing students generally experience high levels of stress, …

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The Approach to Multidisciplinary Oncologic Breast Care

Winston R. Owens, Yang Ding, Diego M. Quirarte, Linden Shih et autres

Breast carcinoma is the second leading cause of cancer-associated death nationwide in women and is also one of the most common in the world. Originally, the diagnosis of breast malignancy left patients with poor prognoses; however, improvements in screening, treatments, and genetic …

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Small-molecule fluorescent probes for imaging and diagnosing ischemia-reperfusion injury

Qingyuan Guo, Yinghui Huang, Jiayu Ding, Junjie Ding et autres

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Management of Avulsive Soft Tissue Ballistic Facial Injuries

Yang Ding, Winston R. Owens, Diego M. Quirarte, Olivia G. Leonovicz et autres

Ballistic facial injuries are rare yet challenging cases for plastic surgeons that often comprise of avulsive tissue loss. They require in-depth assessment and staged reconstruction after patient stabilization. Each anatomic region of the face holds specific considerations that should be prioritized during …

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