Jie Yan

Correction: Camel Whey protein ameliorates type Ⅰ diabetic cardiomyopathy by mitigating oxidative stress, inflammation and apoptosis

Zeyan Peng, Yi-Xiang Wang, Zhili He, Ziwei Chen et autres

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Camel Whey protein ameliorates type Ⅰ diabetic cardiomyopathy by mitigating oxidative stress, inflammation and apoptosis

Zeyan Peng, Jingyang Wang, Zhili He, Ziwei Chen et autres

Abstract Diabetic cardiomyopathy (DCM) is the leading cause of death in diabetic complications. Inflammation and oxidative stress greatly influence the progression of DCM and there are limited therapeutic opportunities. It has been shown that camel whey protein (CWP), a functional dairy ingredient …

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Supplementary Tables 1 - 5. Supplementary Figures 1 - 3 from COMMD3-Mediated Endosomal Trafficking of HER2 Inhibits the Progression of Ovarian Carcinoma

Shiqing Wang, Yuxin Liu, Siyu Li, Yanan Chen et autres

Table S1. Differential receptor proteins detected by mass spectrometry Table S2. Antibodies used in this study Table S3. RT-qPCR primers Table S4. shRNA Table S5. The top 20 candidate genes screened by MAGeCK analysis algorithm Figure S1. The construction of stable cell …

Prevalence and correlates of anxiety disorders and depressive disorders among older adults with non-communicable diseases: results from China Mental Health Survey

Hongmin Ge, Zhaorui Liu, Tong Yue, Yueqin Huang et autres

Background: Anxiety disorders (ADs) and depressive disorders (DDs) are prevalent among older adults with non-communicable diseases (NCDs), yet nationally representative epidemiological data from China remain limited. This study, as a part of the 2013-2015 China Mental Health Survey (CMHS), aimed to assess …

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Metabolic alterations in the umbilical cord blood of pregnant women with uncontrolled type 2 diabetes mellitus: a matched-case comparative study in metabolomics

Muqiu Zhang, Shuting Wan, Jie Yan, Huixia Yang

BACKGROUND: The hyperglycemia in pregnancy (HIP) is classified as the gestational diabetes mellitus (GDM) and pre-gestational diabetes mellitus (PGDM). Metabolomic changes during pregnancy have been suggested to underlie the etiology of HIP, which influence fetal organogenesis and placental development. On one hand, …

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Patterns, delays, and associated factors of help-seeking behaviour for lifetime mood disorders and anxiety disorders: A national representative survey

Shaoling Zhong, Chao Ma, Yueqin Huang, Tingting Zhang et autres

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Epigenetic effects of exercise on improving the adverse placental environment associated with maternal overweight and obesity

Chen Wang, Minghui Liu, Jie Yan, Jie Ning et autres

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Efficacy of para-aortic lymphadenectomy in radical resection of cervical cancer: A systematic review and meta-analysis

Jie Yan, Dan Cheng, Xin Gu, Chengwen Song et autres

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Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus

Jie Ning, Jie Yan, Shuxian Wang, Zifeng Cui et autres

Type 2 diabetes mellitus (T2DM) represents a common complication during pregnancy that affects fetoplacental development. We demonstrated the existence of impaired trophoblast syncytialization under hyperglycemic conditions. However, the exact mechanism remains unknown. RNA N6-methyladenosine (m6A) is an emerging regulatory mechanism of mRNA …

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Abstract 1564: NEU4-mediated desialylation ignites the oncogenic receptors for the dissemination of ovarian carcinoma

Jie Shi, Rui Zhou, Shuo Wang, Yuxin Liu et autres

Abstract Background: Glycosylation profoundly influences the interactions between cancer cells and microenvironmental stromal cells during the peritoneal disseminated metastasis of ovarian carcinoma (OC), which is the major cause of cancer-related death. Although the characteristic cancer glycoconjugates are widely used as biomarkers for …

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Functional analysis of circSNYJ1/miR-142-5p/CCND1 regulatory axis in non-small cell lung cancer

Jie Yan

Non-small cell lung cancer (NSCLC), the most prevalent form of lung cancer, accounts for approximately 85% of all lung cancer diagnoses. Circular RNAs (circRNAs) are non-coding RNAs that play an active role in gene expression regulation, influencing cell growth, migration, and apoptosis. …

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Expression of neuroendocrine markers predicts increased survival in triple-negative breast cancer patients

Chuan Xia, Songjie Shen, Junyi Pang, Longyun Chen et autres

Background: The significance of neuroendocrine (NE) markers in triple-negative breast cancer (TNBC) patients has not been investigated. This study aims to clarify the incidence and prognostic significance of NE marker expression in TNBC, determine its association with other clinicopathological parameters, and further …

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