Peng Mao

Research on Tooth Profile Design and Meshing Performance of Composite Cycloidal Harmonic Drives

Zeyi Yao, Peng Mao, Ronggang Yang, Jingyu Li et autres

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Klebsiella pneumoniae induced ferroptosis by inhibition of the Nrf2/xCT/GPX4 pathway in bovine mastitis: In vivo and in vitro

Peng Mao, Zhihao Wang, Changning Yuan, Kangjun Liu et autres

Klebsiella pneumoniae (K. pneumoniae), a prominent causative agent of mastitis in dairy cattle, remains enigmatic in its pathogenic mechanisms. This study aimed to reveal the effects of K. pneumoniae on mammary glands via the induction of ferroptosis, as well as the protective …

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Klebsiella pneumoniae Induces Ferroptosis and Lactation Dysfunction in Bovine Mastitis via NCOA4-Mediated Ferritinophagy

Peng Mao, Zhihao Wang, Jiangyao Duan, Pengfei Dong et autres

Klebsiella pneumoniae, a major bovine mastitis pathogen, disrupts mammary gland function through poorly understood mechanisms. This study demonstrates that K. pneumoniae infection triggers ferroptosis in bovine mammary epithelial cells (BMECs) via nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy, leading to lactation impairment. RNA …

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Meloxicam Alleviates Oxidative Stress Through Nrf2/HO-1 Activation in Bovine Endometrial Epithelial Cells

Luying Cui, Jiangyao Duan, Peng Mao, Jingyi Zhong et autres

Meloxicam has been identified as an adjuvant therapeutic component in the management of bovine uterine diseases, exhibiting anti-inflammatory and antioxidant effects. However, the mechanisms underlying its antioxidant actions in the context of bovine uterine diseases remain incompletely understood. The objective of this …

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Development and Validation of a Machine Learning-Based Risk Prediction Model for Low Back Pain in Middle-Aged and Elderly Chinese: A SHAP-Interpretable Longitudinal Cohort Study

Anxiang Liu, Xinyu Dou, Bifa Fan, Wenhui Liu et autres

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The Antioxidant Effect of Selenium Is Enhanced by Cortisol Through Nrf2 Pathway in Bovine Endometrial Epithelial Cells

Luying Cui, Jingyi Zhong, Jiangyao Duan, Wanting Li et autres

Background: In dairy cows, the stress-related cortisol level increases the susceptibility to postpartum uterine diseases. Oxidative stress is an important component of the disease process and causes morphological and functional alterations in the bovine endometrium. Selenium (Se) has an antioxidant property, and …

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Fast and High-Precision Elliptic Detection Algorithm Based on Multi-Level Feature Screening

Gao Ma, Ronggang Yang, Peng Mao

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Klebsiella pneumoniae causes mammary gland damage via FNIP1-mediated mitochondrial dysfunction

Pengfei Dong, Changning Yuan, Zhihao Wang, Peng Mao et autres

Klebsiella pneumoniae (K. pneumoniae) is one of the pathogens causing clinical mastitis of bovine. Previous studies have demonstrated that mitochondrial damage and dysfunction are important mechanisms of mastitis in dairy cattle. Folliculin interacting protein 1 (FNIP1) is a major metabolic regulator of …

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DNMT3a ‐mediated methylation of PPARγ promote intervertebral disc degeneration by regulating the NF‐κB pathway

Peng Cheng, Hangzhi Wei, Haiwei Chen, Zhiqiang Wang et autres

Intervertebral disc degeneration (IVDD) is a common chronic musculoskeletal disease that causes chronic low back pain and imposes an immense financial strain on patients. The pathological mechanisms underlying IVDD have not been fully elucidated. The development of IVDD is closely associated with …

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Short-term spinal cord stimulation is an effective therapeutic approach for herpetic-related neuralgia—A Chinese nationwide expert consensus

Wuping Sun, Hongjun Liu, Dong Yang, Tao Sun et autres

Purpose: Short-term spinal cord stimulation (st-SCS) has been widely used to treat herpetic-related neuralgia (HN) in China for several years, but is still heavily debated as it has no strong evidence in clinical application. Therefore, a questionnaire survey among the Chinese pain …

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Evolving fuzzy k-nearest neighbors using an enhanced sine cosine algorithm: Case study of lupus nephritis

Shubiao Wu, Peng Mao, Rizeng Li, Zhennao Cai et autres

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The Relationship of Large‐Artery Atherothrombotic Stroke with Plasma Trimethylamine N‐Oxide Level and Blood Lipid‐Related Indices: A Cross‐Sectional Comparative Study

Dongjuan Xu, Wenfeng Zhao, Juexian Song, Lu Yin et autres

Objective. The role of trimethylamine N‐oxide (TMAO) in cardiovascular diseases has been highlighted. Nevertheless, the associations of large‐artery atherosclerotic (LAA) stroke with TMAO and blood lipid‐related indices are little investigated. Methods. A cross‐sectional comparative study was performed on 50 patients with LAA …

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