Nan Su

Psittacosis chlamydia pneumonia complicated with organizing pneumonia: a case report and literature review

Qiao Li, Xu Sun, Wei Lei, Yehan Zhu et autres

Background Secondary organizing pneumonia (SOP) may develop following infections. Psittacosis, caused by Chlamydia psittaci ( C. psittaci ), is a zoonotic disease transmitted from birds to humans. It can present with a wide spectrum of symptoms, ranging from mild flu-like illness to …

cn (code pays fourni par la source)

Abstract 4366987: Non Muscle Myosin IIC Density and Filament Length Increases in Neonatal Rat Ventricular Myocyte under Isoproterenol Stress

Nan Su, Christopher Li, Jessica Wang

Background: Myh14, encoding non-muscle myosin IIC (NMIIC), is a proposed negative regulator of isoproterenol (ISO)-induced cardiac hypertrophy. ISO upregulated mRNA transcript level of Myh14 in NRVM. In vivo, Myh14 knockout (KO) mice exhibit exaggerated ISO-induced left ventricular (LV) hypertrophy. In neonatal rat …

us (code pays fourni par la source)

Paxlovid plus glucocorticoids treatment in severe Omicron infected patients with hypoxaemia: A prospective multiple-center cohort study

Yuji Wang, Nan Su, Junhong Jiang, Guifang Xu et autres

BACKGROUND: Administration of Paxlovid in early stage has been proved to reduce the risk of hospitalization or death by 89% in mild to moderate COVID-19 patients with high-risk. There were few evidences of Paxlovid in severe COVID-19 patients. RECOVERY study has previously …

cn (code pays fourni par la source)

Case Report: Remission of a patient with complex combination of autoimmune diseases by anti-CD19 CAR-T cell therapy

Xudong Liu, Wenxiang Zhu, Nan Su, Yanyi Ma et autres

CAR-T cell therapy has been proven effective in various autoimmune diseases, with most studies utilizing lentiviral-transduced CAR-T cells. In recent years, retroviral vector-transduced CAR-T cells-characterized by a high positivity rate, stable cell lines, and lower plasmid requirements-have attracted increasing attention. This article …

cn (code pays fourni par la source)

Effects of scalp acupuncture treatment on motor dysfunction in children with spastic cerebral palsy: A multicenter randomized controlled trial

Jun Wang, Xueyan Li, Bingpei Shi, Xiaojuan Shi et autres

cn, us (code pays fourni par la source)

The clinical efficacy of hybrid surgery based on the Waveflex semi-rigid dynamic internal fixation system for the treatment of lumbar degenerative diseases: over three-year follow-up study

Zhiwu Zhang, Jiashen Shao, Nan Su, Xiang Li et autres

OBJECTIVE: To investigate the efficacy and safety of hybrid surgery based on the Waveflex internal fixation system for the treatment of lumbar degenerative disease. METHODS: A retrospective analysis was conducted on 31 consecutive patients who underwent hybrid surgery (fusion combined with non-fusion …

cn (code pays fourni par la source)

Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients

Nan Su, Xiaochuan Li, Shanshan Ren, Lin Wang et autres

Background: Postoperative delirium (POD) manifests as severe mental disorientation, often experienced by elderly patients undergoing surgery, significantly hindering recovery and deteriorating the quality of life. Despite numerous clinical studies, the molecular mechanisms behind POD in elderly patients are still not well understood, …

cn (code pays fourni par la source)

Inhaled Anti-IL-4rα Single-domain Antibody Significantly Reduces FeNO in Moderate-to-Severe Asthma Patients: A Phase 2a Proof-of-Concept Study

Yisong Y. Wan, Nan Su, Yan Li, S. Pei et autres

Abstract Rational: Asthma is a prevalent chronic inflammatory airway disease that poses significant social and economic burdens. Currently, all authorized biologics for asthma treatment are administered systemically. LQ036 is an inhalable, homogeneous, bivalent single-domain antibody (sdAb) for asthma treatment by targeting IL-4Rα. …

cn (code pays fourni par la source)

Percutaneous endoscopic lumbar partial laminectomy assisted by a new miniature parallel surgical robot system: a trail on cadaver specimen

Nan Su, Jiashen Shao, Yu Wang

INTRODUCTION: Robot‑assisted surgery is becoming increasingly popular and its application is expanding to various spinal surgical procedures, including endoscopic spinal surgery. AIM: The aim of this study was to describe a novel small parallel orthopedic surgical robot and evaluate its feasibility in …

cn (code pays fourni par la source)

Rademikibart Treatment for Moderate-to-Severe Uncontrolled Asthma: A Phase 2B Randomized Clinical Trial

Edward Kerwin, Ting Yang, Nan Su, Jiawang Guo et autres

Abstract Rationale Rademikibart (formerly CBP-201) is an IL-4Rα–targeting antibody. Objectives We sought to evaluate rademikibart in adults with moderate-to-severe, persistent, uncontrolled asthma. Methods In this global Phase 2b trial, 322 patients were randomized 1:1:1 to two rademikibart groups (150 mg or 300 …

us, cn (code pays fourni par la source)

Development and Internal-External Validation of Interpretable Machine Learning Models to Predict the Risk of Postoperative Complications after Cranioplasty: A Multicenter, Cohort Study

Wen Li, Bao Wang, T. Li, Y. Ma et autres

Rydberg atomic spectroscopy based on nanosecond pulsed laser excitation

Ting Cai, Jun He, Zhihui Liu, Yao Liu et autres

Through the cascade excitation of 852-nm continuous-wave (CW) laser and 509-nm nanosecond pulsed laser, the electromagnetically-induced transparency (EIT) spectroscopic signals of ladder-type three-level cesium atoms with Rydberg state are obtained by using a room-temperature cesium vapor cell. The power of 509-nm pulsed …