Dan Han

Efficacy and safety of oral Chinese patent medicine combined with quadruple therapy for chronic atrophic gastritis: a systematic review and network meta-analysis

Dan Han, Yi Yang, Bo-yi Wang, Zhan-Ze Ma

Background Chronic atrophic gastritis (CAG) is an important precancerous lesion of gastric cancer, with Helicobacter pylori ( H. pylori ) infection being a major etiological factor. Although quadruple therapy is the first-line treatment for H. pylori eradication, it still has certain limitations. …

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Associations Between Lipid Profiles and Vitamin A and D Deficiencies Among Children and Adolescents in Zhejiang Province, China: A Cross-Sectional Study

Yan Zou, Li-Chun Huang, Mengjie He, Dan Han et autres

Background: This study investigates the associations between lipid profiles, including triglycerides (TGs), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C), and vitamin A (VA) and vitamin D (VD) deficiencies among children and adolescents in Zhejiang Province, China. Methods: …

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Artificial intelligence-based CT histogram parameters differentiating bronchiolar adenoma and lung adenocarcinomas: A two-center study

Wen Zhao, Ziqian Zhao, Yingxia Wang, Haiyan Yang et autres

PURPOSE: Bronchiolar adenoma (BA) is a rare benign pulmonary neoplasm originating from the bronchial mucosal epithelium and mimics lung adenocarcinoma (LAC) both radiographically and microscopically. This study aimed to develop a nomogram for distinguishing BA from LAC by integrating clinical characteristics and …

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Identification of a novel prognostic gene signature associated with therapeutic resistance in hepatocellular carcinoma

Siliang Wang, Shuangshuang Wang, Xu Wang, Yuxiang Sun et autres

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The impact of DRG reimbursement system on appropriate techniques of traditional Chinese medicine—evidence from pilot cities with traditional Chinese medicine hospitals in China

Jin Zhang, Yana Zhou, Dan Han, Chen Zhang et autres

Introduction Given the ongoing development and significant medical role of Traditional Medicine Hospital (TCM) techniques in Chinese TCM hospitals, it is imperative to conduct an assessment on the influence of the gradual implementation of the DRG reimbursement system in W City's three …

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Combined use of green fertilizer and soil conditioner improves soil physicochemical properties, microbial community structure and tobacco quality in continuous cropping

Zihua Zhang, Wuxing Huang, Wei Jia, XU Zi-cheng et autres

Abstract Background Continuous tobacco cultivation over an extended period of time has decreased tobacco production quality, disturbed soil microbial populations and disrupted the soil structure. Therefore, measures to mitigate these ongoing cropping problems must be implemented. Objective To improve the soil quality …

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Clinical application of 90-gene expression test in a patient with occult breast cancer: a case report and literature review

Guojie Xu, Kewei Zhao, Xi Zhou, Liling Zhang et autres

Occult breast cancer is an exceptionally rare disease characterized by ambiguous diagnostic criteria. Currently employed diagnostic methods include breast MRI, PET-CT, and immunohistochemistry; however, challenges in achieving accurate diagnoses persist in certain cases. The utilization of the 90-gene test has been implemented …

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Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) and Vitamin Metabolism: A Nutritional Perspective on an Emerging Environmental Health Issue

C Y Liu, Biao Zhou, Lichun Huang, Dan Han et autres

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals characterized by exceptional stability and potential for bioaccumulation. Ubiquitous in the environment, PFAS can enter the human body through water, air, and dietary sources. Exposure to PFAS has been linked to …

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Efficacy and safety of integrating consolidative thoracic radiotherapy with immunochemotherapy in extensive-stage small cell lung cancer: a real-world retrospective analysis

Qi Zhang, Qian Wang, Xiaomeng Liu, Dan Han et autres

Background: Extensive-stage small cell lung cancer (ES-SCLC) remains a challenging malignancy with a poor prognosis. The integration of immunochemotherapy and combined consolidative thoracic radiotherapy (cTRT) presents a potential paradigm shift in treatment. This study aims to evaluate the real-world efficacy and safety …

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Tenecteplase Thrombolysis for Stroke up to 24 Hours After Onset With Perfusion Imaging Selection: The CHABLIS-T II Randomized Clinical Trial

Xin Cheng, Lan Hong, Longting Lin, Leonid Churilov et autres

BACKGROUND: Whether it is effective and safe to extend the time window of intravenous thrombolysis up to 24 hours after the last known well is unknown. We aimed to determine the efficacy and safety of tenecteplase in Chinese patients with acute ischemic …

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Foramen Facet Spinal Classification for Ossification of the Posterior Longitudinal Ligament on Computed Tomography

Shunmin Wang, Yong Yang, Dan Han, Yongfei Guo et autres

STUDY DESIGN: Retrospective study. OBJECTIVE: To develop and validate computed tomography (CT)-based classification schemes to eliminate ambiguity as much as possible and evaluate the adequacy and clinical value of its classification. BACKGROUND: There is no objective criteria for laminoplasty of more than …

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Vitamin D nutritional status and dietary calcium intake of children and adolescents in Zhejiang Province, China

Yan Zou, Li-Chun Huang, Dong Zhao, Mengjie He et autres

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