Wenjie Lu

A molecular rheostat of ABA signaling coordinates the trade-off between stem growth and drought adaptation

Chenfei Lv, Yuling He, Donghai Zhang, Mengjiao Zhang et autres

Abstract Background Plants balance vegetative growth and stress responses through antagonistic phytohormone crosstalk, notably between abscisic acid (ABA) and cytokinin. However, the genetic architecture and molecular mechanisms driving this adaptive trade-off, particularly in perennial trees, remain elusive. Results Integrating genome-environment and genome-wide …

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The Beclin1‑Targeting stapled peptide suppresses colorectal cancer progression by disrupting EGFR/β-catenin axis

Mingyuan Huang, Rui Chen, Yuying Wen, Minsheng Lan et autres

BACKGROUND: Colorectal cancer (CRC) remains a leading global cause of cancer-related mortality, demanding innovative therapies. Beclin1, a key autophagy and endolysosomal trafficking regulator with tumor-suppressive properties, is frequently downregulated in CRC. Although Beclin1 downregulation correlates with poor clinical outcomes, its regulatory mechanism …

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Psoralidin enhances the sensitivity of breast cancer to cisplatin by targeting Nr1i2

Meigong Zhong, Meimei Wu, Ruizhen Chen, Jiadi He et autres

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Nanostructure-Engineered Optical and Electrochemical Biosensing Toward Food Safety Assurance

Xinxin Wu, Xinai Zhang, Hany S. El‐Mesery, Wenjie Lu et autres

Considering the necessity of food safety testing, various biosensors have been developed based on biological elements (e.g., antibodies, aptamers), chemical elements (e.g., molecularly imprinted polymers), physical elements (e.g., nanopores) as recognition substances. According to the sensing patterns of signal transduction, the biosensors …

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Breaking the Layer Barrier: Remodeling Private Transformer Inference with Hybrid CKKS and MPC

Tianshi Xu, Wenjie Lu, Jinxiang Yu, Yi Chen et autres

This paper presents an efficient framework for private Transformer inference that combines Homomorphic Encryption (HE) and Secure Multi-party Computation (MPC) to protect data privacy. Existing methods often leverage HE for linear layers (e.g., matrix multiplications) and MPC for non-linear layers (e.g., Softmax …

Electrochemical Biosensors Driving Model Transformation for Food Testing

Xinxin Wu, Xinai Zhang, Hany S. El‐Mesery, Wenjie Lu et autres

Electrochemical biosensors are revolutionizing food testing by addressing critical limitations of conventional strategies that suffer from cost, complexity, and field-deployment challenges. Emerging fluorescence and Raman techniques, while promising, face intrinsic drawbacks like photobleaching and matrix interference in opaque or heterogeneous samples. In …

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Advances in Nanozyme Catalysis for Food Safety Detection: A Comprehensive Review on Progress and Challenges

Zeyan Liu, Haili Chen, Xinai Zhang, Qing Sun et autres

The prosperity of enzyme-mimicking catalysis has promoted the development of nanozymes with diversified activities, mainly including catalase-like, oxidase-like, peroxidase-like, and superoxide dismutase-like characteristics. Thus far, the reported nanozymes can be roughly divided into five categories, comprising noble metals, metal oxides, carbon-based nanostructures, …

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Resilient Estimation for Linear and Adaptive Distributed Observer Based on Redundant Information Flow

J. Mo, Xiaobo Zhang, Yangkun Zhang, Wenjie Lu et autres

This addresses the consensus problem of a leader-following multi-agent system (MAS) in the presence of attacked nodes. A distributed observer is proposed deploying the subsequence-reduced algorithm (SRA) based on a thorough analysis of the attack pattern and scope of the cyber-attack model. …

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Exploring Formation and Control of Hazards in Thermal Processing for Food Safety

Zeyan Liu, Xinai Zhang, Hany S. El‐Mesery, Xiaoli Dai et autres

Thermal-processed foods like baked, smoked, and fried products are popular for their unique aroma, taste, and color. However, thermal processing can generate various contaminants via Maillard reaction, lipid oxidation, and thermal degradation, negatively impacting human health. This review summarizes the formation pathways, …

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Correlation between ADGRV1 expression and clinical pathological and prognostic features in breast cancer

Lili Wang, Jiadi He, Jiaqing Chen, Xueqing Zeng et autres

Breast cancer, a leading global health threat with rising incidence, demands precision medicine guided by molecular subtyping. ADGRV1, an adhesion G protein-coupled receptor gene implicated in tumorigenesis but unexplored in breast cancer, was investigated using TCGA data (1,231 cases) and a local …

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Technology Empowering to Safeguard agricultural Products: A review of innovative approaches toward pesticide residue monitoring

Zeyan Liu, Haili Chen, Xinai Zhang, Hany S. El‐Mesery et autres

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Suprabasin promotes gastric cancer liver metastasis via hepatic stellate cells-mediated EGF/CCL2/JAK2 intercellular signaling pathways

Difeng Li, Zhiqing Gao, Zhuojun Zhang, Han Chen et autres

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