Yingying Li

RL–LLMfuzzer: reinforcement learning–guided dual–model differential fuzzing for compiler testing

Donghui Li, Yingying Li, Bo Zhao, Jinlong Xu et autres

Compiler fuzzing faces a fundamental dilemma: traditional rule-based generators easily fall into coverage bottlenecks due to rigid grammar constraints, while Large Language Models (LLMs), despite synthesizing semantically rich code, suffer from extremely low validity rates in their raw outputs, causing a severe …

cn (code pays fourni par la source)

Construction of a dynamic prediction model for diabetic retinopathy risk in adults with adult-onset type 1 diabetes: a real-world longitudinal cohort study

Di Bao, Yingying Li, Chun Mu, Qiuling Xing

Objective: To construct and validate a dynamic prediction model for diabetic retinopathy (DR) risk in adults with adult-onset type 1 diabetes mellitus (T1DM). Methods: A longitudinal cohort of 572 adult-onset T1DM patients from a tertiary hospital in Tianjin, China (2014-2023) was analyzed. …

cn (code pays fourni par la source)

Revealing key genes and molecular mechanisms associated with dietary restriction in ulcerative colitis

Yingying Li, Min Xu, Wen Li, Hao Zhang et autres

Introduction: Ulcerative colitis (UC) is characterized by chronic colonic mucosal inflammation, with its pathogenesis involving multidimensional interactions and limitations in clinical treatment. Dietary restriction (DR) is a commonly used approach for UC patients to alleviate symptoms, and exploring the role of DR-related …

cn (code pays fourni par la source)

Research on Brand Rejuvenation and Transformation Path of Liaoning's Agricultural Products Brands under the Consumption Concept of Generation Z

Yingying Li

Under the policy orientation of expanding domestic demand and activating market vitality, young consumers have become the most dynamic source of growth in the agricultural products market. However, agricultural brands in Liaoning Province generally face the dilemma of "products without brands, quality …

cn (code pays fourni par la source)

Spatiotemporal NO/O 2 -releasing cascade nanozyme microneedles enhance diabetic infected wound healing by modulating the immune microenvironment

Hanqing Zhao, Man Jiang, Fangyuan Chen, Yingying Li et autres

This nanoplatform offers a clinically translatable therapeutic strategy for biofilm-associated diabetic wounds by synergistically combining gas therapy and immune reprogramming.

cn (code pays fourni par la source)

Association between sleep duration and CVD mortality: a prospective cohort study based on middle-aged and elderly chest pain patients

Congcong Lv, Yingying Li, Xue Zhang, Xiaolan Zhang et autres

BACKGROUND: Previous studies have yielded varying conclusions about the relationship between sleep duration and cardiovascular disease (CVD) mortality across different populations. Therefore, it is crucial to examine this relationship specifically within the U.S. chest pain population. OBJECTIVE: This study aims to evaluate …

cn (code pays fourni par la source)

Associations of the neutrophil-to-lymphocyte ratio with all-cause and cardiovascular mortality in patients with chest pain

Zhiqiang Li, Shuhui Wu, Chao Wu, Yue Yin et autres

BACKGROUND: Inflammation is crucial in cardiovascular disease (CVD). While the neutrophil-to-lymphocyte ratio (NLR), a simple inflammatory marker, has been linked to adverse outcomes in various CVD populations, its prognostic significance in patients with chest pain remains unclear. This study aimed to investigate …

cn (code pays fourni par la source)

Reference genome and population genomic analyses reveal insight into herbicide tolerance in Avena fatua L.

Jianan Liu, Ningkun Liu, Wei Yan, Xiaoying Hu et autres

Avena fatua (weedy oat) is a globally pervasive weed, notorious for its adaptability to extreme environments and herbicide tolerance. Here, we present the 10.98-Gb hexaploid genome of A. fatua and a variation map from 768 wild and cultivated oats (A. fatua, A. …

cn (code pays fourni par la source)

Development of a diagnostic model of insulin‐related lipohypertrophy for patients with diabetes mellitus

Xiaohui Li, Yuhua Wei, Dandan Sun, Hongmei Xu et autres

AIMS: To develop a diagnostic model of insulin-related lipohypertrophy for patients with diabetes mellitus. MATERIALS AND METHODS: A cross-sectional study was performed. Between December 2021 and November 2022, a total of 395 diabetic patients treated with insulin were enrolled from a tertiary …

cn, us (code pays fourni par la source)

The central mechanotransducer in osteoporosis pathogenesis and therapy

Chaoyue Liu, Jihao Yang, Zhaoxia Dong, Shuqing Zhao et autres

This review identifies the mechanosensitive ion channel Piezo1 as the central regulator of bone homeostasis. Piezo1 senses mechanical loads in osteocytes, osteoblasts, and bone marrow mesenchymal stem cells (BMSCs), converting them into Ca 2+ -dependent signals that activate key pathways, including CaMKII, …

cn (code pays fourni par la source)

Changes in Cerebral Small Vessel Density and Hemodynamics in CADASIL Patients Revealed by high-resolution Black-Blood MRI and Multi-Delay pCASL

Zidong Yang, Zi-Xuan Liu, Fanhua Guo, Steve Mendoza et autres

Motivation: CADASIL causes reduction in small vessels, disrupted cerebral hemodynamics, and cognitive impairments. Their interrelations remain unclear. Goal(s): To evaluate changes in cerebral small vessel density and cerebral hemodynamics including CBF, ATT, and their contribution to cognitive impairments in CADASIL patients. Approach: …

Impact of a comprehensive healthy lifestyle on pre-diabetes risk and glycaemic control: insights from NHANES 2005–2018

Wenyan Xu, Yingying Li, Dandan Sun, Hongmei Xu et autres

Objective: To evaluate the association between a comprehensive multidimensional healthy lifestyle and the risk of pre-diabetes and glycaemic control markers, specifically glycated haemoglobin (HbA1c) and fasting plasma glucose (FPG), and to conduct subgroup analyses to examine these associations across different populations. Methods: …

cn (code pays fourni par la source)