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Towards conversational diagnostic artificial intelligence

Tao Tu, Mike Schaekermann, Anil Palepu, Khaled Kamal Saab et autres

Abstract At the heart of medicine lies physician–patient dialogue, where skillful history-taking enables effective diagnosis, management and enduring trust 1,2 . Artificial intelligence (AI) systems capable of diagnostic dialogue could increase accessibility and quality of care. However, approximating clinicians’ expertise is an …

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Conditional Language Policy: A General Framework for Steerable Multi-Objective Finetuning

Kaiwen Wang, Rahul Kidambi, Ryan Sullivan, Christoph Dann et autres

Reward-based finetuning is crucial for aligning language policies with intended behaviors (e.g., creativity and safety). A key challenge is to develop steerable language models that trade-off multiple (conflicting) objectives in a flexible and efficient manner. This paper presents Conditional Language Policy (CLP), …

Towards Conversational Diagnostic AI

Tao Tu, Anil Palepu, Mike Schaekermann, Khaled Kamal Saab et autres

At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue could increase accessibility, consistency, and quality of care. However, approximating clinicians' …

Gemini: A Family of Highly Capable Multimodal Models

Gemini Robotics Team, Rohan Anil, Sebastian Borgeaud, Jean-Baptiste Alayrac et autres

This report introduces a new family of multimodal models, Gemini, that exhibit remarkable capabilities across image, audio, video, and text understanding. The Gemini family consists of Ultra, Pro, and Nano sizes, suitable for applications ranging from complex reasoning tasks to on-device memory-constrained …

Disrupted dynamic functional connectivity of hippocampal subregions mediated the slowed information processing speed in late-life depression

Ben Chen, Mingfeng Yang, Xiaomei Zhong, Qiang Wang et autres

BACKGROUND: Slowed information processing speed (IPS) is the core contributor to cognitive impairment in patients with late-life depression (LLD). The hippocampus is an important link between depression and dementia, and it may be involved in IPS slowing in LLD. However, the relationship …

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CYP2C19-rs4986893 confers risk to major depressive disorder and bipolar disorder in the Han Chinese population whereas ABCB1-rs1045642 acts as a protective factor

Ting Zhang, Qingmin Rao, Kangguang Lin, Rongqiao He et autres

BACKGROUND: Genetic risks may predispose individuals to major mood disorders differently. This study investigated the gene polymorphisms of previously reported candidate genes for major depressive disorder (MDD) and bipolar disorder (BPD) in the Han Chinese population. METHODS: Twenty loci of 13 candidate …

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Differences in olfactory functional connectivity in early-onset depression and late-onset depression

Ben Chen, Mingfeng Yang, Meiling Liu, Qiang Wang et autres

Background: Late-onset depression (LOD) and early-onset depression (EOD) exhibit different pathological mechanisms and clinical phenotypes, including different extents of olfactory dysfunction. However, the brain abnormalities underlying the differences in olfactory dysfunction between EOD and LOD remain unclear. Objective: The aim of this …

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