Wei Zhao

Cross-Modal Brain Network Disruptions in Schizophrenia: Insights from Multiplex Modeling and Transcriptomic Associations

Wei Zhao, Hanrui Chen, Hairong Xiao, Yingzhuo Wan et autres

BACKGROUND AND HYPOTHESIS: Conventional multimodal neuroimaging studies in schizophrenia (SCZ) typically model brain networks as independent single-layer systems, overlooking their coordinated cross-modal organization. The molecular and genetic underpinnings of these network alterations remain poorly understood. STUDY DESIGN: We employed a multiplex network …

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White matter microstructure and hemispheric asymmetry alterations in adults who smoke: a connectome-based analysis

Hanlu Zhang, Yuanyuan Shi, C. Y. Li, Wei Zhao

INTRODUCTION: Cigarette smoking poses a pervasive health risk increasingly recognized for its impact on the nervous system, yet its effects on brain structure and organization remain incompletely understood. This study examined how smoking addiction influences white matter (WM) microstructure and the architecture …

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Comparison of clinical efficacy of sequential and single intra-articular injection of platelet-rich plasma in treatment of early/mid-stage knee osteoarthritis

Wei Zhao, Lin Chen, Deli Wang, Xiuli Wei

Objective: To evaluate the clinical efficacy of sequential and single injection of platelet-rich plasma (PRP) in treatment of early/mid-stage knee osteoarthritis (KOA). Methods: Ninety-four patients who were diagnosed of early/mid-stage KOA from 2022 to 2024 were included in this study, involving 39 …

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Altered states and transitions in major depressive disorder and their clinical and molecular associations

Hairong Xiao, Wei Zhao, Xiaoyu Zhang, Shuixia Guo

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G-NodeMixup: Enhancing graph neural networks reachability under extremely limited labels

Ziyu Guan, Beilei Ling, Weigang Lu, Meng Yan et autres

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Research on Facial Expression Recognition Based on Multi-head Attention Mechanism

Wei Zhao, Huiyan Xu

Facial expressions are among the most natural and efficient means of communicating emotions and intentions, accounting for around 55% of human communication when expressing various emotional attitudes. On the other hand, facial expressions are inherently complicated, varied, and comparable. Facial expression recognition …

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Enhanced neuroprotection in Parkinson's disease by neutrophil-biomimetic nanovesicles through autophagy inhibition and apoptosis antagonism

Shengnan Li, Yutong Ren, Xu Xiao, Yuqin Chen et autres

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AASTFNet: An Attention-Aware Spatial-Temporal Fusion Network for Enhanced Pain Intensity Evaluation in Facial Image

Feng Gao, Linbo Qing, Lindong Li, Wei Zhao et autres

Video-based pain intensity assessment offers continuous discomfort quantification, overcoming limitations of conventional subjective methods through automated facial expression analysis. However, current deep learning architectures, despite excelling in extracting spatiotemporal pain features from facial expressions, struggle to localize transient pain signals across consecutive …

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How does ego depletion reduce sports performance in athletes? A systematic meta-analysis

Yan Xu, Yezheng Wang, Ying Tian, Lijuan Wang et autres

Purpose: This meta-analysis focused on exploring whether ego depletion affects sports performance. Subgroup analyses were conducted to compare the magnitude of effect sizes between different ego depletion initiation tasks and which type of sports performance is more susceptible to ego depletion as …

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Transition and dynamic reconfiguration in late-life depression based on hidden Markov model

Hairong Xiao, Wei Zhao, Shuixia Guo

Late-life depression is characterized by persistent emotional distress and cognitive dysfunction, yet understanding the specific brain dynamics and molecular mechanisms involved remains limited. Here, we employed a hidden Markov model to analyze resting-state functional magnetic resonance imaging data from 154 patients with …

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Melatonin Mitigates Acidosis-Induced Neuronal Damage by Up-Regulating Autophagy via the Transcription Factor EB

Yan Shi, Zhaoyu Mi, Wei Zhao, Hu Yue et autres

Acidosis, a common feature of cerebral ischemia and hypoxia, results in neuronal damage and death. This study aimed to investigate the protective effects and mechanisms of action of melatonin against acidosis-induced neuronal damage. SH-SY5Y cells were exposed to an acidic environment to …

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Dysfunction in the hierarchy of morphometric similarity network in Alzheimer’s disease and its correlation with cognitive performance and gene expression profiles

Chuchu Zheng, Wei Zhao, Zeyu Yang, Shipeng Guo

BACKGROUND: Previous research has shown abnormal functional network gradients in Alzheimer's disease (AD). Structural network gradient is capable of capturing continuous changes in brain morphology and has the ability to elucidate the underlying processes of neurodevelopment. However, it remains unclear whether structural …

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