Christoph Markus Sommer

Cortical development dynamics across autism spectrum disorder mouse models

Lena A. Schwarz, Christoph P. Dotter, Sergey V. Isaev, Michela Lisi et autres

, phenotypic convergence across models may reveal common neurobiological processes in autism spectrum disorder (ASD). Here we profiled 251 samples from 11 monogenic mouse models of ASD using single-nucleus multi-omic sequencing across three developmental stages, both sexes and two brain regions. Despite …

at, se (code pays fourni par la source)

Multifold increase in spinal inhibitory cell types with emergence of limb movement

David Vijatovic, Florina Alexandra Toma, Yuri Ignatyev, Zoe P. M. Harrington et autres

As vertebrates transitioned from water to land, locomotion shifted from undulatory swimming to limb-based movement. How spinal circuits and their cell types evolved to support this transition remains unclear. We leverage frog metamorphosis, which recapitulates this transition within a single organism, to …

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sweeneylab/MN_V1_analysis: Motor neuron and V1 inhibitory interneuron analysis code

Christoph Markus Sommer, Robert Hauschild

This is custom analysis code associated with the publication: **Multifold increase in spinal inhibitory cell types with emergence of limb movement *(Cell Reports, 2026)*** Corresponding author: Lora Sweeney (lora.sweeney@ista.ac.at)

at (code pays fourni par la source)

sweeneylab/MN_V1_analysis: Motor neuron and V1 inhibitory interneuron analysis code

Christoph Markus Sommer, Robert Hauschild

This is custom analysis code associated with the publication: **Multifold increase in spinal inhibitory cell types with emergence of limb movement *(Cell Reports, 2026)*** Corresponding author: Lora Sweeney (lora.sweeney@ista.ac.at)

at (code pays fourni par la source)

Biphasic Plate – kontrollierte Instabilität in der Frakturheilung

Christoph Markus Sommer, Moritz F. Lodde, Ladina Hofmann‐Fliri, Michael J. Raschke

The bony consolidation of fractures depends on various factors. Under optimal conditions fracture healing takes place within a few weeks. An essential requirement for fracture healing is the restoration of adequate biomechanical stability with an interfragmentary movement which is as ideal as …

ch, de (code pays fourni par la source)

Läsion des N. ischiadicus nach antegrader Marknagelung proximaler Femurfrakturen

Harry R. Keiser, Philipp Florian Stillhard, Christoph Markus Sommer, Christian Michelitsch

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Light-microscopy-based connectomic reconstruction of mammalian brain tissue

Mojtaba R. Tavakoli, Julia Lyudchik, Michał Januszewski, Vitali Vistunou et autres

Abstract The information-processing capability of the brain’s cellular network depends on the physical wiring pattern between neurons and their molecular and functional characteristics. Mapping neurons and resolving their individual synaptic connections can be achieved by volumetric imaging at nanoscale resolution 1,2 with …

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Super-resolution expansion microscopy in plant roots

Michelle Gallei, Sven Truckenbrodt, Caroline Kreuzinger, Syamala Inumella et autres

Super-resolution methods provide far better spatial resolution than the optical diffraction limit of about half the wavelength of light (∼200-300 nm). Nevertheless, they have yet to attain widespread use in plants, largely due to plants' challenging optical properties. Expansion microscopy (ExM) improves …

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Pilonfraktur

Christian Michelitsch, Philipp Florian Stillhard, Christoph Markus Sommer

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Spinal neuron diversity scales exponentially with swim-to-limb transformation during frog metamorphosis

David Vijatovic, Florina Alexandra Toma, Zoe P. M. Harrington, Christoph Markus Sommer et autres

Vertebrates exhibit a wide range of motor behaviors, ranging from swimming to complex limb-based movements. Here we take advantage of frog metamorphosis, which captures a swim-to-limb-based movement transformation during the development of a single organism, to explore changes in the underlying spinal …

at, us (code pays fourni par la source)

Closed Reduction Followed by Percutaneous Fixation of Acute Femoral Neck Fractures in Young Adults: A Retrospective Cohort Study

Christian Michelitsch, Benedikt Jochum, Andrin Baer, Samuel Haupt et autres

OBJECTIVES: To evaluate the surgical outcomes of femoral neck fractures (FNF) in young adults treated with a closed reduction technique because it pertains to reduction quality, rates of union, and risk factors for complication. DESIGN: Retrospective cohort study with radiograph and electronic …

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Mating-induced release of oxytocin in the mouse lateral septum: Implications for social fear extinction

Cindy P. Grossmann, Christoph Markus Sommer, Ilayda Birben Fahliogullari, Inga D. Neumann et autres

In mammals, some physiological conditions are associated with the high brain oxytocin (OXT) system. These include lactation in females and mating in males and females, both of which have been linked to reduced stress responsiveness and anxiolysis. Also, in a murine model …

de (code pays fourni par la source)