Accès ouvert
2026
article
OpenAlex
David Vijatovic, Florina Alexandra Toma, Yuri Ignatyev, Zoe P. M. Harrington et autres
As vertebrates transitioned from water to land, locomotion shifted from undulatory swimming to limb-based movement. How spinal circuits and their cell types evolved to support this transition remains unclear. We leverage frog metamorphosis, which recapitulates this transition within a single organism, to …
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Accès ouvert
2025
preprint
OpenAlex
Yuri Ignatyev, Stavros Papadopoulos, Mateja Soretić, Jake Yeung et autres
Vertebrates display remarkable diversity of sensorimotor behaviors, each adapted to distinct ecological and survival demands. This diversity raises fundamental questions about the evolutionary origin of motor control: do conserved spinal circuits underlie these behaviors, and how have they diverged across species. Recent …
at, de, us
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Accès ouvert
2024
article
OpenAlex
Swetha K. Godavarthi, Masaki Hiramoto, Yuri Ignatyev, Jacqueline B. Levin et autres
Stable matching of neurotransmitters with their receptors is fundamental to synapse function and reliable communication in neural circuits. Presynaptic neurotransmitters regulate the stabilization of postsynaptic transmitter receptors. Whether postsynaptic receptors regulate stabilization of presynaptic transmitters has received less attention. Here, we show …
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(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Swetha K. Godavarthi, Masaki Hiramoto, Yuri Ignatyev, Jacqueline B. Levin et autres
Abstract Stable matching of neurotransmitters with their receptors is fundamental to synapse function, to achieve reliable and robust communication in neural circuits. Presynaptic neurotransmitters regulate selection of postsynaptic transmitter receptors. However, whether postsynaptic receptors regulate selection of presynaptic transmitters is unknown. Here …
us, at
(code pays fourni par la source)