Haoyu Yang

Nanobody-boosted human ASIC1a endocytosis alleviates chronic pain and anxiety-like behaviours

Kun Luo, Xing-Lei Song, Ming-Hui Gao, Qi Wang et autres

Chronic pain is frequently accompanied by affective disturbances, yet existing analgesics provide limited efficacy and raise substantial safety concerns. The proton-gated ion channel ASIC1a contributes to nociceptive sensitisation and affective pain processing, but the lack of tools that selectively target human ASIC1a …

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Sequential Treatment of Generalized Pustular Psoriasis Combined with Bullous Pemphigoid Using Spesolimab and Dupilumab: A Case Report and Literature Review

Ying Wang, Haoyu Yang, Zhihong Zhang, Haijun Yu et autres

Introduction: Generalized pustular psoriasis (GPP) and bullous pemphigoid (BP) are two distinct but occasionally coexisting inflammatory skin disorders. Their simultaneous presence presents diagnostic and therapeutic challenges. Spesolimab and dupilumab are novel biologics targeting the IL-36 and IL-4/IL-13 pathways, respectively. However, their sequential …

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Effectiveness of nonpharmacological interventions for menopause-related insomnia: A systematic review and Bayesian network meta-analysis

Zhongli Wang, Haoyu Yang, Shutong Li, Cheng Lu et autres

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Transcriptome analysis of OsNCED3 transgenic rice reveals the response mechanism to alkaline stress

Zhonghui Feng, Guanru Lu, Mingming Wang, Miao Liu et autres

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Research on Optimal Agricultural Planning for Risk-Adjusted Crop Yields Based on Monte Carlo Simulation and Bi-Objective Optimization Model

Haoyu Yang, Yuchi Zhang, Junying Zhang

This paper proposes a bi-objective optimization framework to address the challenges of agricultural planning under uncertainty. The framework integrates Monte Carlo simulation to model uncertainties in crop yields, prices, and costs, and a simulated annealing algorithm to optimize planting strategies. The model …

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Association of diabetic nephropathy with lipid metabolism: a Mendelian randomization study

Pengfei Xie, Weinan Xie, Zhaobo Wang, Ziwei Guo et autres

OBJECTIVE: Patients with diabetic nephropathy (DN) often present with lipid profile abnormalities. While associations between these parameters and DN have been suggested, confounding factors obscure causal relationships. This study employed bidirectional Mendelian randomization (MR) to explore these links. METHODS: Using genome-wide association …

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Encapsulation of Perovskite Quantum Dots in Dual-Metal Sites Metal-Organic Frameworks for Efficient Artificial Photosynthesis

Jingjing Wang, Hongjuan Wang, Yun‐Nan Gong, Jingyi Liu et autres

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Adaptive Region Encoding for Efficient Video Object Detection in Edge Computing

Lisha Gao, Jing Tan, Haoyu Yang, Zhenxuan Xu et autres

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ATPIF1 deficiency Significantly Alleviates Citrobacter rodentium-Induced Ulcerative Colitis in Mice

Haoyu Yang, Zhi Li, Yuxin Wang, Lingyun Xu et autres

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Erosion behavior and luminescence properties of Al3+-doped Mg3.5Ge1.25(O,F)6:Mn4+ glass ceramic phosphor

Jiawen Wan, Haohui Jiang, Haoyu Yang, Jinliang Huang et autres

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GPU-Accelerated Inverse Lithography Towards High Quality Curvy Mask Generation

Haoyu Yang, Haoxing Mark Ren

Inverse Lithography Technology (ILT) has emerged as a promising solution for photo mask design and optimization. Relying on multi-beam mask writers, ILT enables the creation of free-form curvilinear mask shapes that enhance printed wafer image quality and process window. However, a major …

A combination of XGBoost and neural network in LIBS spectrum processing for precise determination of critical elements in 620 iron ore samples of various origins

Chenyang Duan, Zhuomin Huang, Yue Jin, Huaqiang Li et autres

cn (code pays fourni par la source)