Xin Zhang

Telomere-to-telomere cattle genome assembly reveals novel introgressions and selection signatures associated with adaptation and energy metabolism

Jinming Huang, Xiuge Wang, Ning Huang, Jinpeng Wang et autres

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Pretreatment intravoxel incoherent motion histogram metrics and clinical characteristics for prediction of perineural invasion status and survival in patients with rectal cancer

Yang Ao, Hao Xu, Xin Zhang, Ping Zheng et autres

OBJECTIVES: To explore intravoxel incoherent motion (IVIM) for evaluation of the perineural invasion (PNI) status and survival in patients with rectal cancer. MATERIALS AND METHODS: The true diffusion coefficient (D), pseudo-diffusion coefficient (D*), and microvascular volume fraction (f) were recorded together with …

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Evaluation of the Efficacy and Safety of a PD-1 Inhibitor Combined with Peg-IFN in Patients with Chronic Hepatitis B: A Protocol for a Prospective Nonrandomized Controlled Trial

Yaping Li, Chenrui Liu, Na Wang, Guoe Gou et autres

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Role and mechanism of sarcosine dehydrogenase in the progression of gallbladder cancer through chemokine pathways

Zhen Gao, Xin Zhang, Hua He

BACKGROUND Sarcosine dehydrogenase (SARDH ) and C-X-C motif chemokine ligand 1 (CXCL1 ) have been identified as potential tumor regulators, with growing evidence linking them to cancer progression. However, their specific roles, regulatory mechanisms, and influence on key signaling pathways remain unclear. …

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Disaccharides as inhibitors of urea-induced soy protein aggregation: A comparative study

Zhaonan Zhang, Xin Zhang, Wenwen Chen, Lianzhou Jiang et autres

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Upregulated CEMIP promotes intervertebral disc degeneration via AP‐1‐mediated change in chromatin accessibility

Shibin Shu, Xin Zhang, Zhenhua Feng, Zhen Liu et autres

BACKGROUND: Intervertebral disc degeneration (IDD), a chronic and multifactorial skeletal disorder, is the primary cause of low back pain. It results in reduced disc height and nucleus pulposus hydration due to proteoglycan loss and nucleus pulposus cells (NPCs) dysfunction within a hypoxic …

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Chinese Expert Consensus on Integrated Chinese and Western Medicine for the Treatment of Tic Disorders

Rong Ma, Sumei Wang, Yi Zheng, Jianmin Chen et autres

OBJECTIVE: Tic disorders are neurodevelopmental conditions that manifest in childhood or adolescence and can significantly impact the quality of life of affected children and their families to varying degrees. Integrated traditional Chinese and Western medicine treatment strategies have demonstrated more pronounced efficacy …

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Effect of time-restricted feeding and caloric restriction in metabolic associated fatty liver disease in male rats

Jiang Deng, Juan Ma, Xin Zhang, Kairuo Wang et autres

BACKGROUND: The prevalence of metabolic associated fatty liver disease (MAFLD) is high. However, there are few studies on the effects of time-restricted feeding (TRF) and caloric restriction (CR) in MAFLD. OBJECTIVES: To investigate the efficacy and mechanism of 4 h TRF and …

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Intestinal Probiotic Lysate Modified Bifunctional Nanoparticle for Efficient Colon Cancer Immunotherapy

Manfang Zhu, Hongkui Chen, Xiaohua Chen, Yueyang Zhang et autres

Background: In cancer immunotherapy, gene therapy has become a promising strategy through the introduction of immunostimulatory components into its formulation. However, ideal non-viral gene delivery platforms capable of simultaneously maintaining a high delivery efficiency and immune activation are still in demand. As …

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Effects of Static Magnetic Fields on Metabolic Diseases

Shiyu Lu, Junjun Wang, Xin Zhang

Review Effects of Static Magnetic Fields on Metabolic Diseases Shiyu Lu 1,2, Junjun Wang 1,* and Xin Zhang 1,2,* 1 High Magnetic Field Laboratory, CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese …

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Comparison of the efficacy and impact on coagulation function of different rituximab dosage regimens in the treatment of membranous nephropathy

Xin Zhang

OBJECTIVE: - in patients with idiopathic membranous nephropathy (IMN), focusing on their effects on coagulation function. METHODS: , n=157) and a low-dose group (1 g, n=166) based on their RTX regimen. We compared clinical remission rates, relapse rates, adverse reactions, and changes …

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Guben Antai Decoction Ameliorates Recurrent Spontaneous Abortion by Suppressing Excessive Autophagy Via Egfr/Pi3k Pathway Modulation

Mingyue Han, Bin Yang, Zhuoxuan Su, Xuebing Li et autres

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