Anshul R. Gupta

Early use of talicabtagene autoleucel in r/r B-acute lymphoblastic leukemia is cost-effective: Improved efficacy, reduced toxicity and healthcare resource utilization support affordable access

Atharva Karulkar, Hasmukh Jain, Devanshi Kalra, Smrithi Ravikumar et autres

Abstract Background: In India, access to curative therapies for relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) remains limited due to restricted availability of allogeneic transplants and monoclonal antibodies. Talicabtagene autoleucel (Tali-cel), a CD19-directed humanized CAR-T cell therapy, was recently approved as the …

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Estimation of Blood Utilization in Elective Surgeries to Formulate Maximum Surgical Blood Ordering Schedule for a Tertiary Care Center in North India

Tamanna Kalra, Saurabh Gupta, Anshul R. Gupta, Nidhi Bansal et autres

Background: Blood transfusion has an essential role in the resuscitation and management of patients undergoing surgical procedures. However, instances of incongruous blood ordering and usage have been reported worldwide, requiring an assessment of blood ordering patterns and addressing the gaps between requisition …

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Indications and outcomes of elective open chest lead extractions

Anshul R. Gupta, John R. Power, Yang Yang, Travis L. Pollema et autres

BACKGROUND: Complications associated with cardiovascular implantable electronic devices may necessitate device and lead removal. An open approach to removal may be electively chosen in cases with high risk of complications or those requiring additional concomitant cardiac surgery. This study aimed to investigate …

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Eosinophilic Endomyocarditis After COVID-19 Infection in a Heart Transplant Recipient

Sara S. Inglis, Anshul R. Gupta, Francisco B. Alexandrino, Marie Christine Aubry et autres

Eosinophilic myocarditis (EM) is a rare cause of heart failure, with high in-hospital mortality associated with fulminant disease. A 61-year-old female transplant recipient was diagnosed with COVID-19 after presenting with 2 days of constitutional symptoms. She developed acute heart failure from EM. …

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Intramuscular degloving injury of rectus femoris in a young elite athlete: A Case Report

Anirban Mallick, Jahnavi Dande, Anshul R. Gupta

Injuries to the rectus femoris muscle are common in sports. It is the second most common cause of lower limb muscle injuries in track and field events and third most common cause of injuries in football. It also hasprevalence among basketball, American …

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Conduction system pacing versus biventricular pacing: Reduced repolarization heterogeneity in addition to improved depolarization

Anshul R. Gupta, Behzad B. Pavri

Abstract Introduction His‐bundle pacing (HBP) and left‐bundle‐area pacing (LBAP) are conduction system pacing (CSP) modalities increasingly used as alternatives to conventional biventricular pacing (BiVP). While effects of CSP on ventricular depolarization have been reported, effects on ventricular repolarization have not. Methods QRS …

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Abstract 8864: Left Bundle Branch Area Pacing is Non-Inferior to His Bundle Pacing in Achieving Physiologic Repolarization and T-Wave Memory Resolution

Anshul R. Gupta, Behzad B. Pavri

Introduction: We have previously reported that His bundle pacing (HBP) results in more physiologic ventricular repolarization as compared to conventional biventricular pacing. Left bundle branch area pacing (LBAP) is increasingly used as the preferred modality of physiologic pacing due to ease of …

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Abstract 16382: The Surface ECG May Provide Information About Left Ventricular Systolic Function in Patients With Right Bundle Branch Block

Anshul R. Gupta, Behzad B. Pavri

Introduction: In patients (pts) with right bundle branch block (RBBB) and heart failure, assessment of left ventricular (LV) function is vital to management, but echocardiograms (ECHO) may not always be readily available. We studied the utility of using the Superimposed Median Format …

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Evaluation of Ventricular Repolarization in Patients Undergoing Cardiac Resynchronization Therapy (CRT) Using Two Modalities: Conventional Biventricular Pacing vs. His-Bundle Pacing

Anshul R. Gupta, Md Pavri

Introduction: Permanent His-bundle pacing (HBP) is being used as an alternative to biventricular pacing (BiVP) for CRT. HBP preserves the physiologic pattern of ventricular activation and markedly reduces ventricular dyssynchrony. While ventricular depolarization with HBP vs. BiVP has been studied, the effects …

Study of functional outcomes of surgical management of acetabular fractures

Anshul R. Gupta, Jitender Singh

The incidence of acetabular fractures is on the rise with the increase in the high velocity road traffic accidents. The goal of the surgical management of acetabular fractures is pain free motion and stability to permit vocational and day to day activities …

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Outcome of operative management of degenerative compressive myelopathy of cervical spine

Anshul R. Gupta, Shahrukhkhan Pathan, Jitender Singh, Ankur Mali

Cervical spondylotic myelopathy is a serious complication of cervical spondylosis. Surgery is increasingly recommended as the preferred treatment strategy for patients with CSM as it can effectively halt disease progression and improve neurological outcomes. Aims of the study were to determine functional …

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A comparative study of granisetrone, dexamethasone and combination of granisetrone-dexamethasone as prophylaxis for postoperative nausea vomiting during laparoscopic surgeries

Deep Chilana, Bhawana Rastogi, Abhishake Kumar, Brig V.P. Singh et autres

Background: In laparoscopic surgeries, insufflation with carbon dioxide triggers vagal afferents on the bowel and peritoneum which induces emesis by activating the vomiting center. It is hypothesized that combined antiemetics with different sites of activity would be more effective than one drug …

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