Xiang-yuan Wu

Deciphering the role of gut microbiota metabolites in bronchiectasis through the perspectives of network pharmacology, Mendelian randomization, and molecular dynamics

Qinzhe Zhang, Li Shang, Shaochu Zheng, Jinling Tang et autres

The role of gut microbiota and their metabolites in respiratory diseases via the "gut-lung axis" has garnered increasing attention, yet their specific mechanisms in bronchiectasis (BIS) remain unclear. This study integrates network pharmacology with bioinformatics approaches, including Mendelian randomization (MR) and molecular …

cn (code pays fourni par la source)

Tanshinone IIA Promotes Hippocampal Neurogenesis in ApoE−/− Mice Through cAMP/PKA/CREB/BDNF Signaling Pathway

Zikang Yang, Xiaoqian Peng, Xiao Zhang, Hongsong Guo et autres

cn (code pays fourni par la source)

Exploring the molecular mechanism of apigenin in treating bronchiectasis based on network pharmacology and molecular docking

Jiahui Han, Yanping Liu, Qinzhe Zhang, Yue Zhou et autres

Bronchiectasis is a complex, heterogeneous inflammatory chronic respiratory disease with an unknown etiology. In the context of increasingly severe drug resistance, there is an urgent need to explore new treatment strategies. Apigenin is a natural flavonoid compound with significant anti-inflammatory and antioxidant …

cn (code pays fourni par la source)

Spatiotemporal patterns and driving mechanism of carbon inequality in Chinese cities

Jiayu Yang, Li Yan, Xinhui Feng, Xiang-yuan Wu et autres

cn (code pays fourni par la source)

Clinical effects, mechanisms and spread of erector spinae plane block and paravertebral block in thoracic and breast surgery: a narrative review

YouChen Zhang, Ye Sun, S L Li, Shijie Ma et autres

Resolving the controversies surrounding the anatomical spread, clinical effectiveness and safety of erector spinae plane block (ESPB) versus paravertebral block (PVB) is crucial for optimizing postoperative pain management in thoracic and breast surgery. This review systematically examines evidence published between 1 January …

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Thymic Microenvironment Remodeling in Cancer Cachexia as a Determinant of Checkpoint Inhibitor Efficacy and Toxicity

Runkai Huang, Yan‐Fang Xing, Xiang-yuan Wu, Zhaohui Shi et autres

ABSTRACT Background The discovery of immune checkpoints links autoimmunity and cancer, with thymus atrophy reportedly causing autoimmune multiorgan inflammation. The impact of cancer cachexia on thymic involution and its clinical significance remains unclear. This study aimed to investigate this effect and its …

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Which urban expansion pattern dominates the variation of carbon emission performance?—Evidence from 244 cities in China

Xinhui Feng, Sensen Wang, Yan Li, Jiayu Yang et autres

cn (code pays fourni par la source)

Elevated VRK2 expression promotes the onset and progression of bronchiectasis

Shaochu Zheng, Yu-Ting Huang, Kangkang Hong, Jinling Tang et autres

Abstract Background Today, the prevalence of bronchiectasis is on the rise worldwide and ranks third among chronic respiratory diseases, yet there is currently no standard treatment. Exploring new drug targets based on a patient’s genetic profile provides new directions to further address …

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A Decade of Progress in Wearable Sensors for Fall Detection (2015–2024): A Network-Based Visualization Review

Fengshi Jing, Hao Ren, Yan Fang, Zhongzhi Xu et autres

Over the past decade, wearable sensors for fall detection have gained significant attention due to their potential in improving the safety of elderly users and reducing fall-related injuries. This review employs a network-based visualization approach to analyze research trends, key technologies, and …

us (code pays fourni par la source)

A Decade of Progress in Wearable Sensors for Fall Detection (2015–2024): A Network-Based Visualization Review

Yifei Li, Pei Liu, Yan Fang, Xiang-yuan Wu et autres

Over the past decade, wearable sensors for fall detection have gained significant attention due to their potential in improving the safety of elderly users and reducing fall-related injuries. This review employs a network-based visualization approach to analyze research trends, key technologies, and …

cn, mo, sg, us (code pays fourni par la source)

A2A Adenosine Receptor as a Potential Therapeutic Target in Cystitis-Induced Bladder Pain: Insights from a Transgenic Autoimmune Cystitis Murine Model

Hai‐Peng Ren, Xiang-yuan Wu, Jian Wang, Yaqun Zhang et autres

cn (code pays fourni par la source)

Bibliometric Analysis and Research Trends in Artificial Intelligence for Medical Imaging in Alzheimer's Disease

Xiang-yuan Wu, Deyi Liang, Changjin Li, Hao Ren et autres

Purpose: To reveal the research hotspots and trends in Alzheimer's Disease medical imaging by bibliometric analysis of the literature on artificial intelligence in this field. Method: Publications on Artificial Intelligence in Alzheimer's Disease Medical Imaging were selected from SCIE and ESCI from …

mo, cn (code pays fourni par la source)