Zihuan Zhang

Ninjurin-1 mediates cell lysis and detrimental inflammation of PANoptosis during influenza A virus infection

Yitian Xu, Ying Zheng, Yan Liu, Wei Cheng et autres

Influenza A virus (IAV) induces ZBP1-mediated PANoptosis, a form of lytic inflammatory cell death characterized by concurrent activation of the pyroptosis, necroptosis and apoptosis pathways. Ninjurin-1 (NINJ1) is a recently identified mediator of plasma membrane rupture but functions diversely in different types …

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Retrospective Analysis of the Clinical Efficacy of Middle Meningeal Artery Embolization Combined With Burr-Hole Drainage in the Treatment of Chronic Subdural Hematoma

Dayong Xia, Jiaqiang Liu, Fei Ding, Zhengqing Hu et autres

OBJECTIVE: To investigate the therapeutic efficacy of middle meningeal artery (MMA) embolization combined with burr-hole drainage in chronic subdural hematoma (CSDH), to establish an evidence base for clinical decision-making. METHODS: A retrospective analysis was conducted on 82 CSDH patients who underwent surgical …

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The Active Ingredients and Mechanisms of Xuefuzhuyu Pills in Treating Hyperprolactinemia Caused by Antipsychotics based on UHPLCQ-TOF-MS/MS, Network Pharmacology, and Molecular Docking Validation

Linliu Du, Zihuan Zhang, Mingyue Liu, Xiufang Zhu et autres

BACKGROUND: XueFuZhuYu pills (XFZY), a traditional Chinese herbal formula originated from the xuefuzhuyu decoction in Correction on Errors in Medical Classics, has a certain clinical effect on the treatment of hyperprolactinemia (HPRL) caused by antipsychotics. However, the active ingredients and mechanism by …

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Laparoscopic versus open surgery in treating patients with gallbladder cancer: a systematic review and meta-analysis

Duo Li, Li Xu, Xiangling Deng, Yongliang Sun et autres

Background: Concerns over the security of laparoscopic radical operation for gallbladder cancer (GBC) persist. This systematic review and meta-analysis attempted to compare the safety and efficacy of laparoscopic surgery (LS) versus open surgery (OS) in the treatment of GBC. Methods: The PubMed, …

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Concerns Regarding Familiarity of the Surgeon-Anesthesiologist Dyad and Postoperative Patient Outcomes for Complex Gastrointestinal Cancer Surgery

Zihuan Zhang, Zhiying Yang

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Stage II Pancreatic Adenocarcinoma after Endovascular Repair of Abdominal Aortic Aneurysm: A Case Report and Literature Review

Zihuan Zhang, Duo Li, Tianxiao Wang, Heyuan Niu et autres

BACKGROUNDS: Concomitant abdominal aortic aneurysms (AAA) and gastrointestinal malignancies are uncommon. Endovascular repair (EVAR) is widely used to treat AAA. However, no consensus exists on the optimal strategy for treating AAA when associated with pancreatic adenocarcinoma. In addition, only few reports of …

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Safety and effectiveness of double microcatheter technique in the treatment of ruptured aneurysms of anterior cerebral circulation

Xintong Zhao, Zihuan Zhang, Jiaqiang Liu, Feiyun Qin et autres

Objective: To evaluate the safety and effectiveness of the double microcatheter technique in the treatment of ruptured aneurysms of the anterior cerebral circulation. Methods: Between 2012 and 2019, 113 patients with ruptured aneurysms of the anterior cerebral circulation were treated using the …

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Comparison of Enterprise stent 2 with 1 in assisting coiling of ruptured aneurysms: a real-world study

Zhenbao Li, Jianwei Xuan, Xinggen Fang, Xintong Zhao et autres

Aim: To investigate the effectiveness and safety of the Enterprise 2 (E2) stent versus the Enterprise 1 (E1) stent in treating ruptured intracranial aneurysms (RIAs) in China. Materials & methods: The authors conducted an electronic medical record analysis for patients with RIAs …

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MRI appearances of hepatic epithelioid hemangioendothelioma: a retrospective study of 57 patients

Xiaolei Liu, Hongwei Yu, Zihuan Zhang, Shuang Si et autres

BACKGROUND: Hepatic epithelioid hemangioendothelioma (HEH) is extremely rare and the MRI features have never been investigated in a large group of patients. METHODS: A retrospective study was designed to review the MRI images of HEH patients. Two radiologists separately evaluated signal intensity …

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Endovascular Treatment of Ruptured Very Small Intracranial Aneurysms: Complications, Recurrence Rate, and Clinical Outcomes

Feiyun Qin, Jiaqiang Liu, Xintong Zhao, Degang Wu et autres

Objective: The aim of this study was to evaluate the safety and efficacy of endovascular treatment for ruptured very small (≤3 mm) intracranial aneurysms (VSIAs). Methods: The clinical data and imaging results for 152 patients with VSIAs treated with coil embolization from …

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Efficacy and Safety of Interferon-Alpha 2b for Patients with Hepatic Epithelioid Hemangioendothelioma: Outcomes of a Case-Series Analysis

Xiaolei Liu, Zihuan Zhang, Jia Huang, Haidong Tan et autres

BACKGROUND: Hepatic epithelioid hemangioendothelioma (HEH) is a rare tumor type. No effective medicine or standard treatment for HEH has been established. PATIENTS AND METHODS: From March 2014 to April 2021, 62 patients with pathologically diagnosed HEH were observed regularly, and interferon-alpha 2b …

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A Modified Treatment Through Point-to-Point Coil Embolization for Direct Carotid Cavernous to Fistula: A Single-Center Result

Zihuan Zhang, Jiaqiang Liu, Bingbing Zhang, Meng‐Liang Zhou et autres

This study aims to assess the safety and efficacy of the modified treatment through point-to-point coil embolization of direct carotid cavernous fistula (dCCF), and evaluate the long-term outcome of patients who underwent the above treatment. A total of 18 patients who suffered …

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