Manu Sharma

Dysbiosis of pro‐inflammatory and anti‐inflammatory salivary cytokines during psoriasis providing a therapeutic window and a valuable diagnostic aid in future

Ravi Kant Sharma, Manu Sharma, Simranjit Singh, Aneet Mahendra et autres

The objective of this article is to evaluate the salivary levels of tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), interleukin-2 (IL-2), and IL-10 in patients with active psoriasis and compare them with those in healthy control subjects. This study included 60 subjects who …

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Cytokine profile in the saliva of patients with active psoriasis revealed significant upregulation of TNF-α, IFN-γ, IL-2 and downregulation of IL-10

Ravi Kant Sharma, Manu Sharma, Aneet Mahendra, Shaveta Sood et autres

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Hyposalivation in patients with psoriasis: Association with severity, inflammatory, and anti‐inflammatory cytokine biomarkers of the disease

Ravi Kant Sharma, Manu Sharma, Aneet Mahendra, Simranjit Singh et autres

The aim of the study is to expound the effect of psoriasis on salivary glands by evaluating the secretion of saliva and salivary cytokine biomarkers in patients with psoriasis. This study was conducted by recruiting 120 subjects that included 60 patients diagnosed …

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Artificial Intelligence Bringing Newer Paradigms in the Diagnosis, Treatment, and Management of Psoriasis

Ravi Kant Sharma, Manu Sharma, Aneet Mahendra, Ujjawal Sharma et autres

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Marginal bone loss in implant placement among Indian patients with fresh extraction socket

Manu Sharma

It is of interest to examine the Marginal Bone Loss (MBL) around a single titanium implant that was immediately loaded and implanted in a healed or new extraction site in the maxilla over a period of five years. This study involved 36 …

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Role of Inflammatory Cytokines in Pathophysiology of Psoriasis

Ravi Kant Sharma, Manu Sharma, Aneet Mahendra, Sunil Kumar

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A comparative evaluation of orthodontic correction in different malocclusions by minimally invasive accelerated orthodontic treatment

Nasir Ahmad Khan, Manu Sharma, Vreiti Sangha

Noonan syndrome-A rare case report

Anwesha Biswas, Prateek Banerjee, Manu Sharma

Noonan syndrome is a developmental disorder characterized by facial dysmorphia, short stature, cardiac defects and skeletal malformations. It may be sporadic or inherited as an autosomal dominant or recessive trait and occurs, one in 1,000-2,500 children. Genetic mutations responsible for Noonan syndrome, …

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Pediatric Oral Vitiligo: Case Report and Literature Review

Manu Sharma, Arishiya Thapasum Fairozekhan, Faraz Mohammed, S.R. Janani et autres

Vitiligo is an acquired hypomelanotic disorder of the skin resulting from loss of functional melanoctyes and it affects approximately 0.5-1% of individuals. 25% of vitiligo in children are diagnosed before 10 years of age. The age of onset of vitiligo in children …

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Multi-System Inflammatory Syndrome in a Child Mimicking Kawasaki Disease

Aman Gupta, Arpinder Gill, Manu Sharma, Megha Garg

There have been recent reports of children presenting with severe multi-system hyperinflammatory syndrome resembling Kawasaki disease (KD) during current COVID-19 pandemic. Exact pathophysiology is unknown, however, most of the children have multi-organ dysfunction and respiratory system involvement is less common compared to …

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Stamp technique- A novel approach in pediatric restorative dentistry

Binish Iftikhar, Sanjay Chachra, Gurpreet Kour, Abhishek Dhindsa et autres

Stamp technique is new and novel method for restoring mainly class I and sometimes class II with accurate occlusal topography with near perfection. Since proprioceptors of stomatognatic system react sensibly under pressure as such occlusal discrepancy after direct restorations, even if it …

Clinical success of fixed space maintainers: Conventional band and loop versus fiber-reinforced composite loop space maintainer

Sanjay Chachra, Abhishek Dhindsa, Manu Sharma

Aim: The study aimed to compare the clinical efficacy of two fixed space maintainers and conventional band and loop and fiber-reinforced composite resin (FRCR) space maintainers. Subjects and Methods: Thirty healthy children, aged 6–8 years were selected having at least two deciduous …

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