Guoqiang Xu

Validity and prognostic value of a novel intraoperative assessment tool for reduction in trimalleolar fractures: the SGSC checklist approach

H F Gao, Guoqiang Xu, Ji Ma, Yijun Wang et autres

BACKGROUND: Trimalleolar fractures present substantial surgical challenges, and the quality of fracture reduction significantly influences patient outcomes. Current intraoperative assessment methods, including fluoroscopy and arthroscopy, each possess inherent limitations when used independently. This study aimed to validate the effectiveness of a novel …

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Postoperative Delirium Following Continuous Fascia Iliaca Compartment Block in Elderly Patients with Hip Fracture: A Case Series and Literature Review

Lei Cao, Guoqiang Xu, Z.H. Liu, Xiaodong Bai et autres

Background: Postoperative delirium (POD) is a common complication in elderly patients with hip fracture. This study aimed to investigate the occurrence of POD in patients receiving continuous fascia iliaca compartment block (CFICB) with an opioid-containing solution, and review current evidence. Case Presentation: …

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Reliability and reproducibility of the STAB classification compared with Neer and AO classifications for proximal humerus fracture-dislocations: a retrospective cohort study of 57 patients

Hua Gao, Zhenyu Liu, Guoqiang Xu, Yijun Wang et autres

BACKGROUND: Proximal humerus fracture-dislocations represent a challenging injury pattern with high complication rates. Current classification systems, including Neer and AO, have limitations in guiding treatment decisions for Neer type VI injuries. This study introduces and validates the STAB classification system, comparing its …

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Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway

Xin Liu, Shuang Liu, Guoqiang Xu, W L Chen et autres

Postmenopausal osteoporosis (PMOP) represents the most prevalent metabolic bone disease among postmenopausal women worldwide. Cathepsin K (CTSK), a key mediator of osteoclastic bone resorption, serves as a critical therapeutic target for PMOP. Through structure-based virtual screening coupled with functional validation, we identified …

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Perioperative Bleeding Risk and Associated Factors in End-Stage Kidney Disease Patients Undergoing Intertrochanteric Fracture Surgery: Implications for Management

Yijun Wang, Hua Gao, Guoqiang Xu, Baojun Wang et autres

Background: End-stage renal disease (ESRD) patients undergoing intertrochanteric fracture surgery face complex coagulation challenges. This study aimed to identify risk factors for coagulation dysfunction in ESRD patients during the perioperative period of intertrochanteric fracture surgery. Methods: This retrospective study included 127 patients …

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Clinical Value of Continuous Fascia Iliaca Compartment Block in Perioperative Management of Elderly Patients with Intertrochanteric Fracture: A Propensity Score-Matched Retrospective Study

Guoqiang Xu, Yuqing Deng, Hua Gao, Baojun Wang et autres

Background: Hip fractures in elderly patients represent a significant healthcare challenge, with substantial morbidity and mortality rates. This study investigated the efficacy of continuous fascia iliaca compartment block (CFICB) in perioperative management. Methods: A retrospective analysis was conducted on elderly patients (≥ …

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Comparison of freehand technique and a novel laser-guiding navigation system in femoral neck-cannulated screw fixation: a randomized controlled trial

Hua Gao, Zhenyu Liu, Xiaodong Bai, Gang Wang et autres

Cannulated screw fixation is essential in treating femoral neck fractures, and the widely used freehand technique has several limitations. Therefore, we designed a new laser-positioning and navigation system and compared its efficacy with that of the traditional freehand technique in the cannulated …

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Fixation of dorsal rim fragments in distal radial intra-articular fractures: Is it necessary

Guoqiang Xu, Gang Wang, Baojun Wang, Xiaodong Bai

Abstract Background To retrospectively analyze the effects of open reduction and internal fixation (ORIF) of AO type C intra-articular fractures on the recovery of wrist function in distal radial fractures with or without dorsal rim fragments and with or without dorsal rim …

Comparison of Freehand Technique and a Novel Laser-Guiding Navigation System in Femoral Neck-Cannulated Screw Fixation: A Randomized Controlled Trial

Hua Gao, Zhenyu Liu, Xiaodong Bai, Gang Wang et autres

Abstract Cannulated screw fixation is essential in treating femoral neck fractures, and the widely used freehand technique has several limitations. Therefore, we designed a new laser-positioning and navigation system and compared its efficacy with that of the traditional freehand technique in the …

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Comparison of freehand technique and a novel laser guiding navigation in distal locking of femoral intramedullary nails: a randomized controlled trial

Hua Gao, Zhenyu Liu, Xiaodong Bai, Guoqiang Xu et autres

Abstract Background Intramedullary nail (IMN) is one of the key essential minimally invasive “weapons” in orthopaedic trauma, while the distal locking is still challenging for surgeons. Although there are various inventions and technologies to improve the locking procedure, there are still problems …

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A Comparative Study of Freehand Technique and A Novel Laser Guiding Navigation in Distal Locking of Femoral Intramedullary Nails

Hua Gao, Zhenyu Liu, Xiaodong Bai, Guoqiang Xu et autres

Abstract Background Intramedullary nail(IMN) is one of the key essential minimally invasive "weapons" in orthopaedic trauma, while the distal locking is still challenging for surgeons. Although there are various inventions and technologies to improve the locking procedure, there are still problems such …

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Intramedullary Nailing for Pathological Fractures of the Proximal Humerus caused by Multiple Myeloma: A Case Report and Literature Review

Guoqiang Xu, gang wang, Xiaodong Bai, Zhenyu Liu et autres

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