Shenxun Shi

A nomogram to predict the risk of cognitive impairment in patients with depressive disorder

Ya‐Ling Jian, Shoumei Jia, Shenxun Shi, Zhongying Shi et autres

This study was to describe the cognitive function status in patients with depressive disorder and to construct a nomogram model to predict the risk factors of cognitive impairment in these patients. From October 2019 to February 2021, a total of 141 patients …

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Protective factors for children with autism spectrum disorder during COVID-19-related strict lockdowns: a Shanghai autism early developmental cohort study

Lingli Zhang, Tai Ren, Hua He, Like Huang et autres

Abstract Background COVID-19 lockdowns increased the risk of mental health problems, especially for children with autism spectrum disorder (ASD). However, despite its importance, little is known about the protective factors for ASD children during the lockdowns. Methods Based on the Shanghai Autism …

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Author Correction: Sparse whole-genome sequencing identifies two loci for major depressive disorder

Na Cai, Tim B. Bigdeli, Warren W. Kretzschmar, Yihan Li et autres

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Effectiveness and safety of Jiuwei Zhenxin granules for treating generalized anxiety disorder: A randomized controlled trial

Xue Wang, Peiran Chen, Shenxun Shi, Wei Chen et autres

Background: Generalized anxiety disorder (GAD) is a chronic disorder characterized by excessive, pervasive, persistent worrying that is difficult to control. Jiuwei Zhenxin granules may be safer and more effective than non-benzodiazepine anti-anxiety drugs for treating GAD. This study aimed to assess the …

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Relative Safety and Efficacy of Two Doses of Tandospirone Citrate for Generalized Anxiety Disorder: A Multicenter Randomized Controlled Trial

Qingwei Li, Haiyin Zhang, Guozhen Lin, Shenxun Shi et autres

Purpose: To determine the relative safety and efficacy of different doses of tandospirone in treating generalized anxiety disorder (GAD). Patients and Methods: This parallel randomized controlled trial enrolled patients with GAD from eight centers in China. The patients were randomly assigned to …

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Safety and Efficacy of Two Doses of Tandospirone Citrate for Generalized Anxiety Disorder: A Multicenter Randomized Controlled Trial

Qingwei Li, Haiyin Zhang, Guozhen Lin, Shenxun Shi et autres

Abstract Background This study aimed to determine the safety and efficacy of different doses of tandospirone to treat generalized anxiety disorder (GAD). Methods This parallel randomized controlled trial involved patients with GAD from eight centers in China between 01/2012 and 09/2018. Patients …

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Ziprasidone Injection for Agitation in Schizophrenic Patients：A Meta-RegressionAnalysis

Liang Su, Yi Xu, Lu Zheng, Shenxun Shi et autres

The therapeutic effect of quetiapine on cognitive impairment associated with 5-HT1A presynaptic receptor involved schizophrenia

Dai Hoon Han, Shenxun Shi, Hong Luo

The cognitive impairment associated with schizophrenia is highly prevalent and affects the overall functioning of subjects. The stimulation of the serotonin 1A receptor is a primary characteristic of some atypical antipsychotic drugs. We measured the levels of cognitive impairment using the Morris …

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Connectivity between the anterior insula and dorsolateral prefrontal cortex links early symptom improvement to treatment response

Hsinsung Yuan, Xiao Li Zhu, Weijun Tang, Yiyun Cai et autres

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Multicenter randomized controlled trial of bifrontal, bitemporal, and right unilateral electroconvulsive therapy in major depressive disorder

Liang Su, Yuping Jia, Shiqiao Liang, Shenxun Shi et autres

AIM: Electroconvulsive therapy (ECT) has been shown to be the most effective and rapid treatment for severe depression. Electrode placement is one of the most important factors that affect ECT's efficacy and side-effects profile. Bifrontal, bitemporal, and unilateral are the three most …

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Trajectory analysis of single-drug therapy for first-episode major depression disorder

Xinsong Yuan, Xiao Li Zhu, Chun Shen, Qiang Luo et autres

Objective To analyze the treatment trajectory and revelant factors of serotonin reuptake inhibitors (SSRIs) in patients with first-episode major depression after single-drug treatment.And to provide ideas for early optimal treatment. Methods This study was a real-world study in which 82 untreated outpatients …

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Frequency-Dependent Relationship Between Resting-State fMRI and Glucose Metabolism in the Elderly

Fangyang Jiao, Zhong-Zhan Gao, Kuangyu Shi, Xize Jia et autres

Both glucose metabolism and blood-oxygenation-level dependent fMRI (BOLD-fMRI) signal reflect hemodynamic features. The objective of this study was to investigate their relationship in the resting-state in healthy participants (n = 18). For fMRI signal, regional homogeneity (ReHo), amplitude of low frequency fluctuations …

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