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Profil bibliographique

Zhen Chai

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

19Publications signalées
192Citations signalées
4Affiliations récentes

Les institutions déclarées

Les domaines associés

3D Printing in Biomedical ResearchAtomic and Subatomic Physics ResearchAdsorption and biosorption for pollutant removalConcrete and Cement Materials ResearchPhysics of Superconductivity and Magnetism

Les publications récentes

Accès ouvert 2026 article OpenAlex

Chronic stress‐induced brain‐derived small extracellular vesicles promote colorectal cancer through Treg differentiation

Huan-he Ni, Yunyan Ling, Ting Tang, Yuyang Liu et autres

Abstract Background Chronic stress is increasingly recognised as a risk factor for poor prognosis in colorectal cancer (CRC) through sustained activation of the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic nervous system, yet the mechanisms by which psychological stress signals are transmitted from the …

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0 citations Clinical and Translational Medicine
Accès ouvert 2026 article OpenAlex

Periodontal ligament stem cells-loaded photocrosslinking GelMA/PEGDA scaffolds for periodontal bone regeneration

Bei Gao, Jie Yao, Yijie Wang, Chen Chen et autres

BACKGROUND: Matrix stiffness is a key feature of the mechanical microenvironment. Periodontal tissue is a multicomponent structure composed of cementum, periodontal ligament, and alveolar bone, and is essential for the physiological reconstruction and stress of teeth. Simulating the stiffness of periodontal tissue …

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2 citations BMC Biotechnology
2025 article OpenAlex

Effect of Matrix Stiffness on the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells in a Three-Dimensional Culture Hydrogel: A Preliminary Study

Shiyang Wu, Zhen Chai, Yanshen Yang, Rong Ding et autres

Two-dimensional (2D) models fail to mimic a three-dimensional (3D) environment in studying mechanosensing of stem cells. Here, we present a 3D culture model to investigate how 3D matrix stiffness influences YAP activation and osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) …

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8 citations ACS Biomaterials Science & Engineering
Accès ouvert 2024 article OpenAlex

Design and Optimization of Casting System for Integrated Longitudinal Beam and Tower Package Based on Al-Si Alloy

Li Heng, Teng Xingyu, Zhen Chai, Zhu Xiaoyong et autres

This study optimized the integrated die-casting of an aluminum alloy longitudinal beam and tower component using no heat-treated aluminum alloy.Leveraging material properties and part geometry, a pouring system was designed and refined through mold flow analysis.This optimized the velocity, temperature distribution, and …

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0 citations Advances in Science and Technology – Research Journal
Accès ouvert 2023 article OpenAlex

Targeting MS4A4A on tumour-associated macrophages restores CD8+ T-cell-mediated antitumour immunity

Yongsheng Li, Zhiyong Shen, Zhen Chai, Yizhi Zhan et autres

Objective Checkpoint immunotherapy unleashes T-cell control of tumours but is suppressed by immunosuppressive myeloid cells. The transmembrane protein MS4A4A is selectively highly expressed in tumour-associated macrophages (TAMs). Here, we aimed to reveal the role of MS4A4A + TAMs in regulating the immune …

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140 citations Gut
2022 conference-paper OpenAlex

Development of non-magnetic VCSEL module for compact atomic magnetometer

Quanpu Liu, Zhen Chai, Jixi Lu, Kaifeng Yin et autres

The integrated Vertical-Cavity Surface-Emitting Lasers (VCSELs) modules have been widely researched and manufactured accompanying with the rapid development of compact atomic magnetometers, atomic gyroscopes, atomic clocks, and the other atomic sensors. For atomic magnetometers operating in the Spin-Exchange Relaxation-Free (SERF) regime, the …

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2 citations

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