Lihua Zhong

The Safety of Interferon‐Based Therapies in Chronic Hepatitis B Patients With Compensatory Cirrhosis

Qiran Zhang, Taoran Geng, Ruirui You, Huiling Xiang et autres

ABSTRACT Aims The tolerance of patients with compensated hepatitis B cirrhosis to interferon (IFN) therapy remains controversial. Therefore, this study aimed to evaluate the safety of pegylated interferon‐alpha in chronic hepatitis B (CHB) patients with compensatory cirrhosis. Methods Data from two prospective …

cn, ca (code pays fourni par la source)

TET2-mediated 5-hydroxymethylcytosine of TXNIP promotes cell cycle arrest in systemic anaplastic large cell lymphoma

Ziqing Yu, Lihua Zhong, Wangyang Tang, Wenfang Zhang et autres

BACKGROUND: 5-Hydroxymethylcytosine (5hmC) modification represents a significant epigenetic modification within DNA, playing a pivotal role in a range of biological processes associated with various types of cancer. The role of 5hmC in systemic anaplastic large cell lymphoma (ALCL) has not been thoroughly …

cn (code pays fourni par la source)

96-Week Treatment of Tenofovir Amibufenamide and Tenofovir Disoproxil Fumarate in Chronic Hepatitis B Patients

Zhihong Liu, Qinglong Jin, Yuexin Zhang, Guozhong Gong et autres

Background and Aims: Tenofovir amibufenamide (TMF) is a novel phosphoramidated prodrug of tenofovir with noninferior efficacy and better bone and renal safety to tenofovir disoproxil fumarate (TDF) in 48 weeks of treatment. Here, we update 96-week comparison results. Methods: Patients with chronic …

cn (code pays fourni par la source)

JAK/STAT3 Signaling Activation Related to Distinct Clinicopathologic Features in Systemic ALK− Anaplastic Large Cell Lymphomas

Jianchao Wang, Lihua Zhong, Weiqing Lin, Wenfang Zhang et autres

Systemic anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma (ALCL) is a group of heterogenous CD30 + T-cell non-Hodgkin lymphomas. Previous studies have highlighted the importance of JAK/STAT3 signaling activation in the molecular pathogenesis of ALK - ALCLs. In the present study, …

cn (code pays fourni par la source)

Hydrogen Attenuates Thyroid Hormone-Induced Cardiac Hypertrophy in Rats by regulating angiotensin II type 1 receptor and NADPH oxidase 2 mediated oxidative stress

Hongxiao Yang, Juncai Bai, Chengchuang Zhan, Shuang Liu et autres

cn (code pays fourni par la source)

Randomised clinical trial: 48 weeks of treatment with tenofovir amibufenamide versus tenofovir disoproxil fumarate for patients with chronic hepatitis B

Zhihong Liu, Qinglong Jin, Yuexin Zhang, Guozhong Gong et autres

BACKGROUND: Tenofovir amibufenamide (TMF) can provide more efficient delivery than tenofovir disoproxil fumarate (TDF). AIM: To compare the efficacy and safety of TMF and TDF for 48 weeks in patients with chronic hepatitis B (CHB). METHODS: We performed a randomised, double-blind, non-inferiority …

cn (code pays fourni par la source)

Secretory carcinoma of the breast with multiple distant metastases in the brain and unfavorable prognosis: a case report and literature review

Hongping Tang, Lihua Zhong, Hongbing Jiang, Yan Zhang et autres

BACKGROUND: Secretory carcinoma of the breast is one of the rarest entities, accounting for less than 0.15 % of all infiltrating breast carcinomas. It has characteristic histopathological and molecular features and, in general, a more favorable prognosis. In this case report, we …

cn (code pays fourni par la source)

The correlation between neonatal vitamin D levels and the risk of childhood asthma attacks

Wenlin Li, Jin Zhou, Shen Liu, Kaihui Xing et autres

BACKGROUND: To explore the correlation between neonatal vitamin D levels and the risk of asthma in children aged 3-9 years. METHODS: A total of 1,534 subjects were selected, and clinical and laboratory test data of all subjects were collected at birth, including …

cn (code pays fourni par la source)

Clinicopathological characterization of follicular helper T-cell-derived peripheral T-cell lymphoma involving Waldeyer’s ring

Jianchao Wang, Wangyang Tang, Wenfang Zhang, Jiesong Wang et autres

cn (code pays fourni par la source)

Secretory Carcinoma of the Breast With Multiple Distant Metastases in Brain and Unfavorable Prognosis: a Case Report and Literature Review

Hongping Tang, Lihua Zhong, Hongbing Jiang, Guie Xie

Abstract Background: Secretory carcinoma of the breast is one of the rarest entities accounting for less than 0.15% of all infiltrating breast carcinomas. It has characteristic histopathological and molecular features and more favorable prognosis. In this case report, we describe a local …

cn (code pays fourni par la source)

Molecular profiling of Chinese systemic anaplastic large cell lymphoma patients: novel evidence of genetic heterogeneity

Lihua Zhong, Zhida Wu, Jianchao Wang, Zai-Zeng Wu et autres

Background: Anaplastic large cell lymphoma (ALCL) is a rare non-Hodgkin lymphoma. A comprehensive understanding of the genetic and clinical heterogeneity of ALCL may help to improve the clinical management of patients with ALCL. However, due to the rarity of the disease, the …

cn (code pays fourni par la source)

Effects of radiofrequency ablation combined with transarterial chemoembolization and antiviral therapy on the prognosis and quality of life in primary chronic HBV-related liver cancer.

Baoling Lu, Lìyǐng Zhū, Xiaofang Wang, Lihua Zhong et autres

PURPOSE: To investigate the effects of radiofrequency ablation (RFA) combined with transarterial chemoembolization (TACE) and antiviral therapy on the prognosis and quality of life in primary chronic hepatitis B virus (HBV)-related liver cancer. METHODS: A total of 80 hepatitis B patients complicated …

cn (code pays fourni par la source)