Wenbin Song

Multi-Omics Profiling Identifies a High-Risk Subgroup of Breast Cancer Stem Cells for Prognostic Stratification and Personalized Treatment

Guixin Wang, Ziyi Chen, Yao Tian, Yuxin Zhu et autres

Background: Breast cancer is the most prevalent malignancy among females worldwide.Extensive research has highlighted cancer stem cells (CSCs) as critical drivers of tumor initiation, progression, recurrence, and therapy resistance.However, the heterogeneity of breast cancer stem cells (BCSCs) and their dynamic roles within …

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Integration of Single-Cell and Bulk Transcriptomes to Identify a Poor Prognostic Tumor Subgroup to Predict the Prognosis of Patients with Early-stage Lung Adenocarcinoma

Zijian Shi, Linchuang Jia, Baichuan Wang, Shuo Wang et autres

Our study provided a comprehensive characterization of the TME in LUAD through integrative single-cell and bulk transcriptomic analyses. We identified dynamic transitions from normal epithelial cells to tumor cells, revealing the heterogeneity and evolution of malignant LUAD cells. The novel prognostic model …

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A prognostic model for anoikis-related genes in pancreatic cancer

Wenbin Song, Haiyang Hu, Zhengbo Yuan, Hao Yao

Anoikis, a distinct form of programmed cell death, is crucial for both organismal development and maintaining tissue equilibrium. Its role extends to the proliferation and progression of cancer cells. This study aimed to establish an anoikis-related prognostic model to predict the prognosis …

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Enhanced afterglow behavior of a new Eu2+: Sr2Al2SiO7 green phosphor co-doped with different cations Nd3+, Dy3+, Ho3+, Tm3+ and Yb3+

Shengyi Liu, Duan Gao, Li Wang, Wenbin Song et autres

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Integrating Bulk and Single-cell RNA-seq to Construct a Macrophage-related Prognostic Model for Prognostic Stratification in Triple-negative Breast Cancer

Hongmeng Zhao, Xuejie Zhou, Guixin Wang, Yue Yu et autres

Background: Triple-negative breast cancer (TNBC) is a poor prognostic subtype of breast cancer due to limited treatment.Macrophage plays a critical role in tumor growth and survival.Our study intends to explore the heterogeneity of macrophage in TNBC and establish a macrophage-related prognostic model …

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Supplementary Table 1 from Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

Le Tao, Jianxin Qiu, Ming Jiang, Wenbin Song et autres

Pearson's correlation analysis of key genes in our pathway according to BLCA data set

Supplementary Figure 1 from Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

Le Tao, Jianxin Qiu, Ming Sen Jiang, Wenbin Song et autres

Pearson's correlation analysis of IL8, IL1 and HIF1A according to BLCA data set

Supplementary Table 1 from Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

Le Tao, Jianxin Qiu, Ming Jiang, Wenbin Song et autres

Pearson's correlation analysis of key genes in our pathway according to BLCA data set

Supplementary Figure 1 from Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

Le Tao, Jianxin Qiu, Ming Sen Jiang, Wenbin Song et autres

Pearson's correlation analysis of IL8, IL1 and HIF1A according to BLCA data set

Data from Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

Le Tao, Jianxin Qiu, Ming Jiang, Wenbin Song et autres

Abstract The tumor microenvironment impacts tumor progression and individual cells, including CD4+ T cells, which have been detected in bladder cancer tissues. The detailed mechanism of how these T cells were recruited to the bladder cancer tumor and their impact on bladder …

Data from Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

Le Tao, Jianxin Qiu, Ming Jiang, Wenbin Song et autres

Abstract The tumor microenvironment impacts tumor progression and individual cells, including CD4+ T cells, which have been detected in bladder cancer tissues. The detailed mechanism of how these T cells were recruited to the bladder cancer tumor and their impact on bladder …

Supplementary Figures 1 - 5 from Gambogic Acid Induces Apoptosis in Imatinib-Resistant Chronic Myeloid Leukemia Cells via Inducing Proteasome Inhibition and Caspase-Dependent Bcr-Abl Downregulation

Xianping Shi, Xin Chen, Xiaofen Li, Xiaoying Lan et autres

Supplementary figure 1. Molecular weight of proteins. All the molecular weight of proteins detected in this current study were labeled. M.W: molecular weight. Supplementary Fig. 2. KBM5 and KBM5-T315I cells were exposed to IM in various concentrations for 48 hours, and then …