Jiangang Wang

Oblique illumination line confocal imaging with adjustable aperture for wafer defect detection

Xuewen Wang, Jiangang Wang, Ning Liu, Yu Wei Huang et autres

cn (code pays fourni par la source)

Narirutin downregulates USP15 to inhibit the NLRP3 ubiquitination in HDM-induced allergic rhinitis

Jianing Yang, Jingmei Chai, Yunong Li, Jiangang Wang et autres

cn (code pays fourni par la source)

Ginsenoside Rh1 Alleviates Allergic Rhinitis by Mediating Mitochondrial Autophagy via Activation of the AMPK/ULK1/FUNDC1 Pathway

Jiangang Wang, Yalin Zhang, Jingmei Chai, Jianing Yang et autres

Ginsenoside Rh1, a bioactive compound derived from ginseng, exhibits notable anti-inflammatory and antioxidant effects and has shown promising therapeutic potential in the treatment of allergic diseases. However, its exact role in allergic rhinitis (AR) and the underlying molecular mechanisms remain inadequately understood. …

cn (code pays fourni par la source)

Different GJA8 missense variants reveal distinct pathogenic mechanisms in congenital cataract

Zexuan Li, Xinyue Deng, Yanna Cao, Hongbo Xu et autres

cn (code pays fourni par la source)

Public views on genetics and genetic testing of sudden unexplained death: A survey of the public in China

Ming Qi, Xutao Hong, Xiaoling Chen, Jinyuan Wang et autres

cn (code pays fourni par la source)

Retraction Note: NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells

Ling Liu, Jingjing Chen, Mengyao Cao, Jiangang Wang et autres

cn (code pays fourni par la source)

Design and synthesis of cabotegravir derivatives bearing 1,2,3-triazole and evaluation of anti-liver cancer activity

Huaxia Xie, Longfei Mao, Gaolu Fan, Ziyuan Wu et autres

Based on the structure of the anti-HIV drug cabotegravir, we introduced 1,2,3-triazole groups with different substituents to obtain 19 cabotegravir derivatives and tested their activity against HepG2 cells. The proliferation of HepG2 cells was examined following treatment with derivatives. Most of the …

cn, us (code pays fourni par la source)

Population genomics reveals extensive inbreeding and purging of mutational load in wild Amur tigers

Tianming Lan, Haimeng Li, Le Zhang, Minhui Shi et autres

Abstract The inbreeding is a big threat for the persistence of genetic diversity in small and isolated populations of endangered species. The homozygous genome could exacerbate inbreeding depression by introducing homozygous deleterious alleles in the population. However, purging of inbreeding loads as …

cn, se (code pays fourni par la source)

Role of ACSL5 in fatty acid metabolism

Qin Luo, Avash Das, Federico Oldoni, Panyun Wu et autres

Free fatty acids (FFAs) are essential energy sources for most body tissues. A fatty acid must be converted to fatty acyl-CoA to oxidize or be incorporated into new lipids. Acyl-CoA synthetase long-chain family member 5 (ACSL5) is localized in the endoplasmic reticulum …

cn, us (code pays fourni par la source)

Oligomeric β-Amyloid Suppresses Hippocampal γ-Oscillations through Activation of the mTOR/S6K1 Pathway

Yali Wang, Jiangang Wang, Shuling Guo, Fangli Guo et autres

Neuronal synchronization at gamma frequency (30-100 Hz: γ) is impaired in early-stage Alzheimer's disease (AD) patients and AD models. Oligomeric Aβ1-42 caused a concentration-dependent reduction of γ-oscillation strength and regularity while increasing its frequency. The mTOR1 inhibitor rapamycin prevented the Aβ1-42-induced suppression …

cn, gb, ru (code pays fourni par la source)

The chromosome-scale genome of the raccoon dog: Insights into its evolutionary characteristics

Tianming Lan, Haimeng Li, Shangchen Yang, Minhui Shi et autres

genes may explain their high reproductivity. Enriched GO terms in energy metabolism and positively selected immune genes were speculated to be closely related to the diverse immune system of raccoon dogs. In addition, we found that several expanded gene families and positively …

cn (code pays fourni par la source)

Chromosome-level Genome of the Muskrat (Ondatra zibethicus)

Haimeng Li, Minhui Shi, Qing Wang, Tian Xia et autres

The muskrat (Ondatra zibethicus) is a semi-aquatic rodent species with ecological, economic, and medicinal importance. Here, we present an improved genome assembly, which is the first high-quality chromosome-level genome of the muskrat with high completeness and contiguity assembled using single-tube long fragment …

cn (code pays fourni par la source)