Salvador González

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

Azahara Rodríguez-Luna, Alicia Zamarrón, Cristina García‐Muñoz, Juan‐Carlos Hernández‐Rodríguez et autres

BACKGROUND/PURPOSE: Visible light (VL), and particularly high-energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes. As …

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Potential Blood Biomarkers Predicting Treatment Response in Psoriasis: A Systematic Review and Meta-Analysis

José María Villa-González, Irene Arevalo-Ortega, M.R. González Hermosa, Salvador González et autres

Background/Objectives: Psoriasis is a chronic immune-mediated inflammatory disease primarily driven by the interleukin (IL)-23/T helper 17 (Th17) pathway. Despite multiple systemic therapies, treatment response varies considerably, and many patients require sequential switching. We aimed to evaluate circulating blood-derived biomarkers associated with response …

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Prospective subtyping of head and neck basal cell carcinoma by dermoscopy and handheld RCM

Yannick S. Elshot, Wouter Ouwerkerk, Biljana Zupan‐Kajcovski, Mijke Bol et autres

BACKGROUND: The management of head and neck basal cell carcinoma (BCC) relies on diagnostic biopsies. However, substantial discordance exists between biopsy and excisional specimens. Handheld reflectance confocal microscopy (HH-RCM) could reduce invasive biopsies. OBJECTIVES: The primary objective was to assess the diagnostic …

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74493 Evaluation of a Topical Formulation combining Aspalathus linearis and Polypodium leucotomos extracts in the prevention of skin hyperpigmentation and molecular alterations induced by visible light

Sérgio Schalka, Michelle Sabrina, Alia Shafiq, M.A.R.I.A. VITALE et autres

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Potential Value of a Combination of Polypodium leucotomos and Aspalathus linearis Extracts in Protecting Vitamin D Receptor Levels During Skin Oxidative Stress

Marta Mascaraque, M. Gallego-Rentero, Andrea Barahona-Lopez, Paula Cano et autres

Background/Objectives: Vitamin D (VD), through the interaction with its receptor (VDR), plays essential roles in the skin. VDR-mediated signaling prevents cancer development and improves prognosis, making it an appealing target for therapy. However, VD cutaneous synthesis begins with solar exposure, which is …

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Monitoring the Effectiveness of Noninvasive or Minimally Invasive Therapies for Nonmelanocytic Lesions Using Reflectance Confocal Microscopy: A Systematic Review

José María Villa-González, M.R. González Hermosa, Marco Ardigò, Salvador González

In vivo reflectance confocal microscopy (RCM) enables monitoring of non-melanocytic skin cancers (NMSC) treated with non-invasive or minimally invasive therapies. This systematic review analyzed studies on NMSC treated with these therapies and monitored by RCM. A total of 56 articles were included, …

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From Diagnosis to Therapy in Primary Cutaneous Extramammary Paget’s Disease: A Systematic Review of Non-Invasive and Non-Surgical Approaches

Francesco D’Oria, Francesco Piscazzi, Matteo Liberi, Giulio Foggi et autres

Background/Objectives: Extramammary Paget’s disease (EMPD) is a rare cutaneous malignancy arising in areas rich in apocrine glands that poses diagnostic and therapeutic difficulties. Although surgery remains the standard of care, achieving clear margins is challenging and recurrence rates are high. This review …

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PSA response, tolerability, and survival in elderly patients with metastatic prostate cancer treated with apalutamide

Susana Boso Alonso, Salvador González, R. D ́Ambrosi, Sharon Fernandez et autres

Impact of SBRT on PSA response and survival in metastatic hormone-sensitive prostate cancer treated with apalutamide

Susana Boso Alonso, Salvador González, C. Domingo Boluda, Filipa Pereira et autres

Novelty of digital press stereolithography (DPS) with MIDAS system in crown fabrication: marginal and internal fit evaluation

Cristian Abad‐Coronel, S Martín Proaño, Salvador González, L Jerely Chico et autres

BACKGROUND: The marginal and internal fit of full-coverage crowns is essential for their long-term clinical success. Computer-aided design and manufacturing (CAD/CAM) technologies have enhanced the precision of restorations. However, the performance of emerging three-dimensional (3D) printing systems, such as the Midas system …

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Reddish/bluish benign lesions evaluated by dermus SkinScanner

Carmen Cantisani, Phyllida Kerstin Hamilton-Maikle, Mattia Di Segni, András Bánvölgyi et autres

Angiomas and blue nevi are common benign skin lesions with overlapping clinical appearances that can mimic malignancy, such as melanoma. This study evaluates the role of dermoscopy-assisted high-frequency ultrasound (DA-HFUS) in characterizing these lesions. Five cases (2 angiomas, 3 blue nevi) were …

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Non-Invasive Diagnostic Imaging in Kaposi Sarcoma Evaluation

Carmen Cantisani, Antonio Di Guardo, Marco Ardigò, Mariano Suppa et autres

Background and Clinical Significance: Kaposi sarcoma (KS) is a rare angio-proliferative mesenchymal tumor that predominantly affects the skin and mucous membranes but may involve lymph nodes and visceral organs. Clinically, it manifests as red-purple-brown papules, nodules, or plaques, either painless or painful, …

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