2026
article
OpenAlex
Hailin He, Zhi-Yang Guan, Zeyan Zhong, Zhong Guo-xing et autres
This retrospective study established the first comprehensive genetic epidemiological profile of thalassemia in the childbearing‑age population (n = 343,580) of Huizhou, a major Hakka center in Guangdong, China, over a decade (2015–2024). The overall carrier rate was 12.23%, comprising 8.04% α‑thalassemia, 3.58% …
cn
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Yi Kong, Yousheng Wang, Xingwang Wang, Li Guo et autres
Purpose Prenatal phenotypic manifestations of genetic disorders associated with NSD2 variants remain poorly characterized. This study presents our institutional experience with the prenatal diagnosis of NSD2 ‐associated genetic disorders, specifically Rauch–Steindl syndrome (RAUST), aiming to improve understanding of both the molecular and …
cn, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Zhichang Yang, Wenhao Li, Bing Yu, Minfang Liu et autres
Multidrug-Resistant Organism (MDRO) refers to bacteria that are Resistant to three or more types of antibiotics in clinical use. The global health threat posed by multidrug-resistant (MDR) bacterial pathogens and their cross-species transmission necessitates rigorous Surveillance. This urgency is amplified in China …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
S. S. Lv, Jianhong Chen
Objective: To investigate the clinical efficacy of the self-designed Nuangong Zhitong Ling in primary dysmenorrhea (PD) of cold coagulation syndrome. Methods: Forty patients with PD of cold coagulation syndrome who were treated with the self-designed Nuangong Zhitong Ling in our hospital from …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Dina Chen, Zhiyang Guan, Shaohui Huang, Zeyan Zhong et autres
Objectives To investigate the prevalence, hematological characteristics and optimal cutoff values for mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) in carriers with combined α- and β-thalassemia (αβ-thalassemia) in the Huizhou region of southern China.Methods The epidemiological investigation, including prevalence assessment …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Guoxing Zhong, Jiajia Wu, Zeyan Zhong, Dina Chen et autres
Background: Non-invasive prenatal testing (NIPT), which made use of cell-free DNA (cffDNA) in maternal blood, was currently being applied all over the world for the detection of common chromosome abnormalities. It had relatively high sensitivity and specificity. Nevertheless, studies demonstrated that false …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Zeyan Zhong, Gong Zheng, Dina Zhu, Yongqiong Liu et autres
BACKGROUND: Thalassemia is one of the most prevalent monogenic disorders in tropical and subtropical regions, imposing significant familial and social burdens on local populations. It is caused by point mutations or structural variations (SVs) in the α- or β-globin gene clusters. Due …
cn
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Weidong Xiao, Mingquan Gao, Banghui Mo, Xie Huang et autres
Background: Endoplasmic reticulum (ER)-targeted phototherapy has emerged as a promising approach to amplify ER stress, induce immunogenic cell death (ICD), and enhance anti-tumor immunity. However, its impact on the antigenicity of dying tumor cells remains poorly understood. Methods: Laser activation of the …
cn
(code pays fourni par la source)
2025
other
OpenAlex
Zhiyang Guan, Dina Chen, Zeyan Zhong, Zhiyong Wu et autres
OBJECTIVE: To analyze the hematological characteristics of patients with three common deletional β-thalassemia and concomitant α-thalassemia in Huizhou, Guangdong province. METHODS: A total of 1 335 subjects of childbearing age with hemoglobin F (Hb F) ≥ 5% at the Huizhou First Maternal …
cn
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Hao Chen, Nian Liu, Li Huang, Dongxin Huai et autres
Peanut (Arachis hypogaea L.) is a great plant protein source for human diet since it has high protein content in the kernel. Therefore, seed protein content (SPC) is considered a major agronomic and quality trait in peanut breeding. However, few genetic loci …
cn
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Hua Ning, Guang Wei, Jianhong Chen, Zhiwen Wang et autres
The mechanism of Y on H/H 2 adsorption performance of Mg 17 Al 12 were studied by the density functional theory. We obtained that for the Y-adsorbed systems, Y tended to occupy on the bridge site between adjacent Mg atoms. For the …
cn
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Hongfeng Lin, Jianhong Chen, Zhongyan Zhang, Yuxu Wang
Abstract In the current study, Fe3O4/Ag nanohybrids demonstrating high efficiency in liver cancer ferroptosis therapy and MR imaging were synthesized using a facile one-pot approach. Subsequently, their morphology, chemical composition, structure, Fenton reaction activity, and magnetic resonance (MR) contrast effect were systemically …
cn
(code pays fourni par la source)