Yaqin Wang

Fe-Doped Carbon Dots Functionalized Nanoelectrode for In Situ Monitoring of Metabolism-Associated ROS Changes in Single Microglia

Hong Jiang, Yaqin Wang, Xiao-Yang Dong, Dong Zhao et autres

In metabolic reprogramming, reactive oxygen species (ROS) serve not only as harmful byproducts but also as essential signaling molecules that drive reprogramming processes to establish new metabolic homeostasis. Therefore, the in situ monitoring of ROS changes during metabolic reprogramming is crucial for …

cn (code pays fourni par la source)

Effects of water activity on the flavor characteristics and drying quality of asparagus lettuce: The alteration of cell wall structure and water distribution

Gaoqi Ye, Zixuan Yang, Ziyuan Wang, Guangmin Liu et autres

cn (code pays fourni par la source)

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

Zhimin Zhu, Xiaomei Wu, Yan Hu, Xiaolan Bian et autres

Alternative splicing (AS) is an important posttranscriptional process that increases proteomic complexity of eukaryotes. Through the selective inclusion or exclusion of exons, AS fine-tunes gene expression and underpins diverse biological processes. Recent research revealed that AS is controlled not only by spliceosomal …

cn (code pays fourni par la source)

Role of elevated temperature and acetyl distribution in gelation of konjac glucomannan: Molecular dynamics insights into chain entanglement and aggregation

Yaqin Wang, Xiaoxuan Chen, Guohua Zhao, Yun Zhou

cn (code pays fourni par la source)

Physics-informed acoustic metamaterials design via forward-inverse surrogate modelling for gearbox weak signal detection

Yaqin Wang, Xiaoxi Ding, Zhiming Wang, Jiaheng Gao et autres

Acoustic metamaterials have garnered significant research interest due to their unique wave-manipulation capabilities, with potential applications spanning noise control, subwavelength imaging, and non-destructive testing. However, conventional design paradigms rely on trial-and-error experimentation, biomimetic inspiration, and finite element analysis (FEA). These approaches suffer …

cn (code pays fourni par la source)

Identification of Crucial Genes Associated With MYCN‐Driven Neuroblastoma Based on Single‐Cell Analysis and Machine Learning

Jiasi Zhang, Yichen Lei, Yaqin Wang, Yu Wen et autres

BACKGROUND: Neuroblastoma (NB) with MYCN amplification is strongly correlated with high-risk stratification and poor prognosis. However, the underlying mechanisms remain incompletely understood. Elucidating these pathways is critical for advancing personalized treatments for MYCN-driven NB. METHODS: We performed single-cell transcriptomic analysis comparing NB …

cn (code pays fourni par la source)

The safety and effectiveness of sintilimab versus camrelizumab, both plus targeted drugs, in advanced hepatocellular carcinoma

Chenglong Zhao, Qiong-Ni Zhu, Xiaoyan Qian, Zhonghua Fu et autres

Objectives: We aimed to evaluate the effectiveness and safety of sintilimab versus camrelizumab, both plus targeted drugs, for advanced hepatocellular carcinoma (HCC) in the real world. Then the effectiveness was compared between sintilimab-lenvatinib and camrelizumab-apatinib. Methods: Patients diagnosed as advanced HCC were …

cn (code pays fourni par la source)

A CYP80B enzyme from Stephania tetrandra enables the 3'-hydroxylation of N-methylcoclaurine and coclaurine in the biosynthesis of benzylisoquinoline alkaloids

Yaoting Li, Yuhan Feng, Yu Gao, Jiatao Zhang et autres

cn (code pays fourni par la source)

[Study on the gene expression and regulation mechanisms of fibroblasts in acute inflammatory response].

Meng Du, Hanjing Liao, Yaqin Wang, Zong-Jie Zhao et autres

Objective To investigate the gene expression and regulatory mechanisms of mouse embryonic fibroblasts (MEFs) under inflammatory conditions, aiming to elucidate the role of MEFs in inflammatory responses and provide a foundation for discovering anti-inflammatory drugs that act by modulating MEF function. Methods …

cn (code pays fourni par la source)

Physiological and nutritional responses of two pakchoi (Brassica chinensis) cultivars to different red-blue light ratios in controlled environment

Hadiqa Anum, Yaqin Wang, Yangmei Li, Guoqing Sun et autres

There is a growing interest in cultivating pakchoi under controlled environment agriculture. However, research on establishing the ideal environmental conditions for growing pakchoi in plant factories remains insufficient. Therefore, in this study, we investigated the optimal red-to-blue light ratio for enhancing pakchoi …

cn, de (code pays fourni par la source)

Roles of different polysaccharides on the structures of alginate-based Bigel beads and co-delivery of bioactives

Guangmin Liu, Yuxuan Wang, Jingyi Yang, Yaqin Wang et autres

Bigels are novel soft-solid materials, which attract increasing attentions in the food industry. In this study, bigel beads based on alginate hydrogel and monoglyceride oleogel were developed, and their structures were modified by adding various polysaccharides (pectin, carrageenan, chitosan, xanthan gum and …

cn (code pays fourni par la source)

PD1+ Treg cell remodeling promotes immune homeostasis within peripheral blood and tumor microenvironment after microparticles-transarterial chemoembolization in hepatocellular carcinoma

Zhizhong Ren, Yaqin Wang, Dandan Jiang, Ying Liu et autres

The effects of transarterial chemoembolization (TACE) on the systemic immune in hepatocellular carcinoma (HCC) are not well understood. We aimed to reveal the temporal and spatial changes in the immune profile of peripheral blood and tumor tissues in HCC patients following TACE. …

cn (code pays fourni par la source)