Jeongsoo Lee

T-bet high atypical memory B cells exhibit effector memory features in mRNA vaccine recipients 2256789

Seunghwan Son, Jeongsoo Lee, Sung‐Dong Cho, Joon Seok et autres

Abstract Introduction T-bet high B cells, also referred to as atypical or double-negative 2 (DN2) B cells, are defined by high expression of the transcription factor T-bet (TBX21) and typically expand during chronic infections and autoimmune conditions. In severe viral infections such …

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Author Correction: A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity

Joon Seok, Sung‐Dong Cho, Jeongsoo Lee, Yunseo Choi et autres

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Inhalation Delivery of Interferon-λ-Loaded Pulmonary Surfactant Nanoparticles Induces Rapid Antiviral Immune Responses in the Lung

Chan Hee Gil, Chanhee Oh, Jeongsoo Lee, Mincheol Jang et autres

The interferon-λ (IFN-λ)-regulated innate immune responses in the airway expand our understanding toward antiviral strategies against influenza A virus (IAV). The application of IFN-λ as mucosal antiviral therapeutic is still challenging, and advanced research will be necessary to achieve more efficient delivery …

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A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity

Joon Seok, Sung‐Dong Cho, Jeongsoo Lee, Yunseo Choi et autres

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SARS-CoV-2 RBD-specific atypical memory B cells exhibit effector memory-like features in multi-dose mRNA vaccination

Jeongsoo Lee, Sung‐Han Kim, Eui‐Cheol Shin, Su‐Hyung Park

Abstract Memory B cell is a heterogenous population and such heterogeneity is a focus of active investigation. How distinct subsets of memory B cells respond to repeated novel antigen challenges such as SARS-CoV-2 in human remains a subject of vigorous research. We …

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Safety and immunogenicity of a recombinant DNA COVID-19 vaccine containing the coding regions of the spike and nucleocapsid proteins: Preliminary results from an open-label, phase 1 trial in healthy adults aged 19–55 years

Jin Young Ahn, Jeongsoo Lee, You Suk Suh, Young Goo Song et autres

Abstract Background We investigated the safety and immunogenicity of two recombinant COVID-19 DNA vaccine candidates in first-in-human trials. GX-19 contains plasmid DNA encoding SARS-CoV-2 spike protein, and GX-19N contains plasmid DNA encoding SARS-CoV-2 receptor binding domain (RBD) foldon and nucleocapsid protein (NP) …

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Immunodeficiency risk score for prediction of mortality by parainfluenza virus infection in patients with hematologic malignancy

Jeongsoo Lee, Jiwon Jung, Min Jae Kim, Yong Pil Chong et autres

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FCT 1-7 : Comparison of sodium thiosulfate solution and mixture of diflucortone valerate and isoconazole nitrate in Malassezia infection

Nuri Na, Jeongsoo Lee, Yong-Woo Choi, Osung Kwon et autres

Background: Superficial infection of malassezia occurs in the forms of pityrosporum folliculitis, pityriasis versicolor, seborrheic dermatitis, etc. We can use systemic antifungal agent, topical antifungal agent, zinc pyrithione, urea and so on. Objectives: The purpose of this study is to compare the …

P074 : Correlation factor analysis for zoster meningitis and postherpetic neuralgia

Yong-Woo Choi, Osung Kwon, Nuri Na, Jeongsoo Lee et autres

Background: Herpes zoster (HZ) is caused by reactivation of latent varicella-zoster virus infection. Aseptic meningitis associated HZ is a rare complication of HZ. Also postherpetic neuralgia (PHN) is a neuropathic pain syndrome characterized by pain that persists for months to years after …

Comparing Two Mycobacterium tuberculosis Genomes from Chinese Immigrants with Native Genomes Using Mauve Alignments

Sungweon Ryoo, Jeongsoo Lee, Jee Youn Oh, Byeong Ki Kim et autres

Background The number of immigrants with tuberculosis (TB) increases each year in South Korea. Determining the transmission dynamics based on whole genome sequencing (WGS) to cluster the strains has been challenging. Methods WGS, annotation refinement, and orthology assignment for the GenBank accession …

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Comparing Two Mycobacterium tuberculosis Genomes from Chinese Immigrants with Native Genomes Using Mauve Alignments

Sungweon Ryoo, Jeongsoo Lee, Jee Youn Oh, Byeong Ki Kim et autres

BACKGROUND: The number of immigrants with tuberculosis (TB) increases each year in South Korea. Determining the transmission dynamics based on whole genome sequencing (WGS) to cluster the strains has been challenging. METHODS: WGS, annotation refinement, and orthology assignment for the GenBank accession …

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PWM half-bridge zeta converter utilizing resonant technique for reduced peak current

Jae-Il Baek, Jeongsoo Lee, Keon‐Woo Kim, Jung-Kyu Han et autres

The PWM half-bridge zeta (HBZ) converter is one of the most attractive dc-dc converters for wide-input-voltage applications due to its extended duty ratio above 0.5 and soft switching capability. However, it suffers from large peak current stress in the primary and secondary …

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