Chunhong Hu

Development of Nomogram for Predicting Postoperative Progression Risk in High-Risk Thymoma and Thymic Carcinoma Utilizing Clinical and Preoperative CT Features

Qian Meng, Nan Jiang, Jun Chen, Chunjiao Weng et autres

Background: Computed tomography (CT) features and clinical characteristics have been shown in recent studies to be effective predictive indicators for risk stratification of thymic epithelial tumors. High-risk thymoma and thymic carcinoma (HRT-TC) are highly aggressive and are associated with poor prognoses. The …

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Genome-wide identification of bromodomain family genes and functional analysis of GhBRD34 in cotton (Gossypium spp.)

H B Wu, Xiaoxiao Liu, Yumeng Li, Wei Y et autres

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BGB-3111-218: Single-arm, open-label, multicenter study of the Bruton tyrosine kinase (BTK) inhibitor zanubrutinib (zanu) in patients with CD79B-mutated Relapsed/Refractory (R/R) diffuse large B-cell lymphoma (DLBCL)

Li Wang, Fei Li, Qingyuan Zhang, Hui Zhou et autres

Abstract Background Zanu, a potent, specific next-generation BTK inhibitor with a favorable safety profile, is approved in over 70 countries globally for the treatment of multiple B-cell malignancies. Pts with R/R DLBCL face a poor prognosis, and the CD79B mutation is an …

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Sediment Scouring and Silting Threshold in the Middle and Lower Reaches of the Yangtze River Before and After the Three Gorges Project

Minghui Shen, Chunhong Hu, Shuai Guo, Hongling Shi et autres

Understanding sediment transport under varying flow regimes and its associated scouring–silting responses is fundamental for analyzing the coupled dynamics of hydrology and river morphology. However, in large alluvial rivers strongly modified by human interventions such as dam operations, identifying critical thresholds of …

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A review of digital twin-enabled intelligent manufacturing with a focus on the wooden furniture industry

Chunhong Hu, Jian‐Gang Zhu

Digital twin, which integrate multi-physical, multi-scale, and multi-disciplinary attributes through real-time synchronization, virtual-reality interaction, and high-fidelity modeling, enable the seamless integration of physical entities with their digital counterparts and have garnered significant attention in both academia and industry, particularly in intelligent manufacturing. …

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Sugemalimab versus placebo, in combination with platinum-based chemotherapy, as first-line treatment of metastatic non-small-cell lung cancer (GEMSTONE-302): 4-year outcomes from a double-blind, randomised, phase 3 trial

Caicun Zhou, Ziping Wang, Meili Sun, Lejie Cao et autres

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Abstract 3278: Neoadjuvant EGFR-TKI therapy reshapes tumor immune microenvironment in resectable EGFR-positive non-small cell lung cancer

Fang Wu, Fan Dan, Yingzhe Zhang, Wenliang Liu et autres

Abstract Background: Patients with EGFR-positive non-small cell lung cancer (NSCLC) do not respond as well to immunotherapy as patients without an EGFR mutation. Nevertheless, recent studies indicate that subsequent immunotherapy following EGFR-TKI treatment may be effective in EGFR-positive NSCLC. Given the critical …

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Dual-Energy CT-Based Thrombus Radiomics Can Predict Functional Outcome of Intravenous Thrombolysis in Acute Ischemic Stroke

Yuzhu Ma, Ying Zhao, Yao Dai, Ziyang Song et autres

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Association of cardiovascular disease and CIRS‑G and ACE‑27 comorbidity indices with pathological complete response of non‑small cell lung cancer to neoadjuvant chemoimmunotherapy

Xingsheng Hu, Ping Zhong, Chaoyuan Liu, Xianling Liu et autres

Neoadjuvant chemoimmunotherapy (NCIO) is a new and effective treatment for cancer, but its efficacy in treating certain patients is unclear. We previously found that comorbidity was an independent factor associated with the pathological complete response (pCR) of non-small cell lung cancer (NSCLC) …

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Prognostic value of pretreatment peripheral blood hemoglobin×lymphocyte/monocyte ratio in patients with nasopharyngeal carcinoma.

Chao Deng, Zui Chen, Jie Ling, Yangchun Xie et autres

OBJECTIVES: Peripheral whole blood cell counts have been used as prognostic indicators for various cancers, but their predictive value in nasopharyngeal carcinoma remain unclear. This study aims to evaluate the prognostic significance of the pretreatment hemoglobin×lymphocyte/monocyte ratio (HLMR) in non-recurrent, non-metastatic NPC …

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Long-term follow-up of zimberelimab in relapsed or refractory classic Hodgkin lymphoma: Insights from the phase Ⅱ YH-S001-04 clinical trial

Hai Bai, Hui Liu, Jie Cui, Xiaoyan Ke et autres

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T1 mapping-based radiomics in the identification of histological types of lung cancer: a reproducibility and feasibility study

Jianqin Jiang, Yong Xiao, Jia Liu, Lei Cui et autres

BACKGROUND: T1 mapping can quantify the longitudinal relaxation time of tissues. This study aimed to investigate the repeatability and reproducibility of T1 mapping radiomics features of lung cancer and the feasibility of T1 mapping-based radiomics model to predict its pathological types. METHODS: …

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