Zhirong Zhang

Erratum: pH-Triggered Copper-Free Click Reaction-Mediated Micelle Aggregation for Enhanced Tumor Retention and Elevated Immuno-Chemotherapy against Melanoma

Miao Deng, Rong Guo, Shuya Zang, Jingdong Rao et autres

Corn Straw Co-Feeding Enhances Polystyrene Biotransformation in Mealworms through Redox Regulation and Gut Microbiota-Host Interactions

Meng-Qi Ding, Zhirong Zhang, Jia-Yi Wang, Lei He et autres

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Optimizing aerosol therapy in mechanically ventilated acute respiratory distress syndrome: a delivery-fidelity framework

Zhao-kun Fan, Zhirong Zhang, Ying-ying Shen, Wei Chen et autres

Aerosol therapy is frequently used in adults with acute respiratory distress syndrome (ARDS) receiving invasive mechanical ventilation, yet its clinical effects remain difficult to interpret because prescribed dose is not equivalent to lung exposure. This Mini Review examines aerosol therapy as a …

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Aging-Induced Physicochemical Changes in Petroleum- and Biobased Microplastics Influence Depolymerization and Gut Microbiota in Tenebrio molitor Larvae

Yuan Tian, Meng-Qi Ding, Jie Ding, Xin-Ran Ren et autres

In this study, we evaluated the influence of physicochemical aging on the biological processing and depolymerization performance of polyethylene (PE) and polylactic acid (PLA) by Tenebrio molitor larvae, with the goal of improving insect-based plastic treatment strategies. PE and PLA subjected to …

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BTR-SDN: A Blockchain-Enabled Trusted Routing Scheme for SDN Interdomain

Shuang Yang, Zhongsheng Jiang, Wansu Pan, Yuquan Tang et autres

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Correction to “Antitumor and Antimetastasis Activities of Heparin-based Micelle Served As Both Carrier and Drug”

Ling Mei, Yayuan Liu, Huajin Zhang, Zhirong Zhang et autres

PCK1 deficiency promotes MASH-HCC progression by 12-HETE-induced CD8 + T cell dysfunction

Kang Wu, Li Luo, Yi Liu, Kai Wang et autres

Background Metabolic dysfunction-associated steatohepatitis-related hepatocellular carcinoma (MASH-HCC) has been reported to be less responsive to immune checkpoint inhibitors, which may be associated with metabolic reprogramming of tumour cells and abnormal tumour microenvironment. Objective Here, we aim to investigate the role of gluconeogenic …

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Monocyte Membrane-Fused Liposomes for Enhanced Targeted Treatment of Mesangioproliferative Glomerulonephritis

Yujia Wang, Jiali Fu, Yan Yuan, Ting Li et autres

The rising incidence of end-stage renal disease, with mesangioproliferative glomerulonephritis (MsPGN) as a major contributor, underscores the urgent need for safe and effective therapeutic strategies. In this study, we developed monocyte membrane-fused liposomes loaded with celastrol (M-Lipo@CLT) to exploit the innate inflammatory …

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Nanoparticle-mediated targeted protein degradation (NanoTPD): Principles, rational design and mechanisms of degradation

Yunting Zhang, Keran Wang, Yixiang Yang, Tao Gong et autres

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Preparation and performance study of a new type of dual-ion dual-network gel for mining

Xiangming Hu, Hao Fang, Chen Guang Xu, Zhirong Zhang et autres

To address the limitations of coal mine fire prevention and extinguishing gels—such as pipeline clogging, transport losses, and weak adhesion to coal surfaces—this study developed a dual-ion, dual-network gel (CMC–Fe–AlCit/PAM–PVA) system. Sodium carboxymethyl cellulose (CMC) served as the primary network, polyacrylamide (PAM) …

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Modular Nanoassemblies Mimicking p62 Aggregates for Targeted Organelle Sequestration and Degradation against Breast Cancer

Yuai Li, Yunting Zhang, Jingwen Wang, Yujie Che et autres

Selective autophagy relies on multivalent recognition by receptors like SQSTM1/p62 to form aggregates that cluster disperse organelles, undergoing liquid–liquid phase separation to facilitate their clearance and maintain cellular homeostasis. Inspired by this, we present the multivalent nanoparticle-based organelle targeting chimera (NanoTAC Org …

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Deep Learning-Enhanced Dual-Component Gas Sensor Based on Wavelength Modulation Spectroscopy

Huidi Zhang, Xiaonan Zhang, Jun Tang, Yaohan Li et autres

Considering the challenge of qualitative and quantitative detection for gas mixtures caused by spectral overlap, a deep learning-enhanced dual-component gas sensor based on wavelength modulation spectroscopy (WMS) with the 2 f /1 f signals is proposed, achieving simultaneous detection of exhaled carbon …

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