Hongbing Liu

Photosynthetic acclimation is a key contributor to exponential growth of a desert plant in Death Valley summer

Karine Prado, Bo Xue, Jennifer E. Johnson, Sterling Field et autres

us, cn (code pays fourni par la source)

Hydroquinone Hydroxypropyl-β-cyclodextrin Inclusion Complex Based Topical Cream as an Effective Treatment of Melasma by Releasing Hydroquinone in a Controlled Manner

Yinling Mu, Hongbing Liu, Yiyu Liu, Wanbing Pan et autres

cn (code pays fourni par la source)

How evolution repeatedly builds complexity: a case study with C4 photosynthesis in Blepharis (Acanthaceae)

Matt Stata, Ming‐Ju Amy Lyu, Hongbing Liu, Shifeng Cheng et autres

Summary With over 60 parallel origins representing evolutionary replicates, C4 photosynthesis is well‐suited for studying complex trait evolution. However, lineages with diverse C3–C4 intermediate species are scarce, leaving uncertainty in models of C4 evolution. Phenotypic characterization of 28 living species of Blepharis …

ca, cn (code pays fourni par la source)

Comorbidity patterns and immune-metabolic differences in patients with acute-episode of schizophrenia spectrum disorders

Guoping Wu, Zhe Dong, Zhongcai Li, Song Chen et autres

Patients with schizophrenia (SCZ) face multiple health challenges due to the complication of chronic diseases and psychiatric disorders. Among these, cardiovascular comorbidities are the leading cause of their life expectancy being 15-20 years shorter than that of the general population. Identifying comorbidity …

cn (code pays fourni par la source)

Structure and Biosynthesis of Aridomycins Reveal a Glycosylated Prodrug Strategy for Self-Resistance

Hongbing Liu, Shannon I. Ohlemacher, Robert O’Connor, Rahim Rajwani et autres

Polyketides, nonribosomal peptides, and their hybrids constitute a major class of clinically important antibiotics. To avoid self-toxicity, producing organisms must employ mechanisms of self-resistance. Here, we describe the structures, biosynthesis, and self-resistance strategy of the aridomycins, new linear polyketide antibiotics. Using NMR …

us (code pays fourni par la source)

Irinotecan and dexamethasone prodrug co-loaded liposomes for the treatment of breast cancer

Meizhu Chen, Hongbing Liu, Muse Ji, Dongmei Shi et autres

cn (code pays fourni par la source)

Cardiovascular comorbidities in Chinese inpatients with schizophrenia spectrum disorders

Zhe Dong, Gang Wu, Hongbing Liu, Song Chen et autres

Cardiovascular diseases (CVDs) are the leading cause of premature mortality in patients with schizophrenia spectrum disorders (SSDs). However, the detailed categorization of these conditions remains insufficiently explored. This study aims to identify CVDs comorbidity patterns among inpatients with SSDs and to investigate …

cn, us, au (code pays fourni par la source)

Evolutionary diversification of C2 photosynthesis in the grass genus Homolepis (Arthropogoninae)

Joyce Pereira Alvarenga, Matt Stata, Rowan F. Sage, R. C. Patel et autres

BACKGROUND AND AIMS: To better understand C4 evolution in monocots, we characterized C3-C4 intermediate phenotypes in the grass genus Homolepis (subtribe Arthropogoninae). METHODS: Carbon isotope ratio (δ13C), leaf gas exchange, mesophyll (M) and bundle sheath (BS) tissue characteristics, organelle size and numbers …

br, ca, cn, au (code pays fourni par la source)

MDM2 drives resistance to Osimertinib by contextually disrupting FBW7-mediated destruction of MCL-1 protein in EGFR mutant NSCLC

Jiaxin Liu, Lingyun Wei, Qing Miao, Sutong Zhan et autres

BACKGROUND: Overcoming resistance to Osimertinib in epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC) is clinically challenging because the underlying mechanisms are not fully understood. The murine double minute 2 (MDM2) has been extensively described as a tumor promotor …

cn (code pays fourni par la source)

The genome of Eleocharis vivipara elucidates the genetics of C3–C4 photosynthetic plasticity and karyotype evolution in the Cyperaceae

Hongbing Liu, Hang Zhao, Xiuli Li, Yi Zuo et autres

ABSTRACT Eleocharis vivipara, an amphibious sedge in the Cyperaceae family, has several remarkable properties, most notably its alternate use of C3 photosynthesis underwater and C4 photosynthesis on land. However, the absence of genomic data has hindered its utility for evolutionary and genetic …

cn, be, nl, ca, us (code pays fourni par la source)

Harnessing landrace diversity empowers wheat breeding

Shifeng Cheng, Cong Feng, Luzie U. Wingen, Hong Cheng et autres

Abstract Harnessing genetic diversity in major staple crops through the development of new breeding capabilities is essential to ensure food security 1 . Here we examined the genetic and phenotypic diversity of the A. E. Watkins landrace collection 2 of bread wheat …

cn, gb, au, es, Éthiopie, Égypte, ch, rs, Kenya, sa, de (code pays fourni par la source)

Glucocorticoids-based prodrug design: Current strategies and research progress

Hongbing Liu, Muse Ji, Peifu Xiao, Jingxin Gou et autres

Attributing to their broad pharmacological effects encompassing anti-inflammation, antitoxin, and immunosuppression, glucocorticoids (GCs) are extensively utilized in the clinic for the treatment of diverse diseases such as lupus erythematosus, nephritis, arthritis, ulcerative colitis, asthma, keratitis, macular edema, and leukemia. However, long-term use …

cn (code pays fourni par la source)