Shu Zhang

Connectome-based growth models reveal individual heterogeneity and neurophysiological subtypes of subthreshold depression

Guanmao Chen, Xiaoyi Sun, Pan Chen, Xuan Bu et autres

Subthreshold depression (StD) confers a high risk for major depression and is characterized by substantial individual clinical heterogeneity. However, the neurobiological substrates underlying this heterogeneity remain largely unknown. Using a large multisite resting-state functional MRI dataset including 1203 healthy participants and 197 …

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Association between mushroom consumption and digit span performance among middle-aged and older community-dwelling Japanese: the NILS-LSA project

Shu Zhang, Djibril Mari Ba, Yukiko Nishita, Chikako Tange et autres

= 0.0447) tests, with benefits most pronounced at moderate to high intake levels. These findings suggest that regular mushroom consumption, measured in grams per day, may enhance short-term and working memory in middle-aged and older adults, highlighting a potentially simple dietary approach …

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Heatmap of 10-year disability risk according to the frailty–intrinsic capacity (FR-IC) index in older Japanese adults

Rei Otsuka, Shu Zhang, Yukiko Nishita, Chikako Tange et autres

jp (code pays fourni par la source)

Development and Validation of the Healthy Longevity Index for Personalized Healthy Aging in Primary Care: Cross-National Retrospective Analysis

Hsi‐Yu Lai, Shu Zhang, Rei Otsuka, Shih‐Tsung Huang et autres

Background: Measuring and promoting healthy aging at an individual level remains challenging as promoting healthy longevity requires real-time, personalized tools to assess risk and guide interventions in clinical practice. Objective: This study aimed to develop and validate a novel Healthy Longevity Index …

tw, jp (code pays fourni par la source)

A Synergistic Cu/Ca Dual‐Doping Strategy for High‐Stability and Fast‐Charging O3‐Type Cathode in Sodium‐Ion Batteries

Jing Feng Wu, Wenbo Zhou, Shu Zhang, Jiahao Wang et autres

Abstract The O3‐type layered oxide cathodes are highly promising for sodium‐ion batteries due to their high specific capacity. However, the sluggish kinetics and poor interlayer stability caused by narrow layer spacing and volumetric stress accumulation limit their fast‐charging and long‐cycle performance. Herein, …

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Interactive Associations of Age, Apolipoprotein E ε4 Gene, Physical Activity, and Physical Functioning on Processing Speed

Ricardo Aurélio Carvalho Sampaio, Yukiko Nishita, Chikako Tange, Shu Zhang et autres

OBJECTIVES: This study investigated the interactive associations of age, apolipoprotein E ε4 (APOE4) genetic status, physical activity energy expenditure (PAEE), and physical functioning on processing speed over a 10-year period. DESIGN: In this longitudinal study, participants underwent biennial assessments from 2002 to …

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Efficacy of Myofascial Trigger Point Dry Needling in Treatment of Primary Dysmenorrhea: A Study Protocol for a Three-Arm Randomized Controlled Trial

Yanxia Sun, Lihua Yang, Shu Zhang, Wei Cheng et autres

Background and Objective: Primary dysmenorrhea carries substantial medical, social, and economic burdens, leading many patients to seek low-risk complementary and alternative therapies, such as acupuncture. Myofascial trigger point dry needling (MTrP-DN) has recently gained attention as a potential treatment, though evidence remains …

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Corrigendum to “Association between diet quality evaluated using the Meiji nutritional profiling system and serum 25-hydroxyvitamin D levels in Japanese adults and older adults: A cross-sectional study from the NILS-LSA” [Hum. Nutr. Metab. 41 (2025) 200328]

Tao Yu, Shu Zhang, Ryota Wakayama, Tomohito Horimoto et autres

Risk factors associated with cognitive frailty development through different transition pathways among community-dwelling older adult Japanese individuals: insights from the NILS-LSA project

Shu Zhang, Yukiko Nishita, Chikako Tange, Kanae Furuya et autres

BACKGROUND: The risk factors on the transition from robustness to cognitive frailty (CF), characterized by concurrent cognitive impairment and physical frailty (PF), may vary through different transition routes. METHODS: Data from the National Institute for Longevity Sciences-Longitudinal Study of Aging (2000−2012) were …

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Data from multi-national aging cohorts show dysregulated metabolic pathways in people with physio-cognitive decline

Yi‐Long Huang, Wei‐Ju Chang, Chao‐Hsiung Lin, Shu Zhang et autres

Physio-cognitive decline (PCD) represents a dual impairment of mobility and cognitive function in aging populations, significantly increasing risks of disability, dementia, and mortality. Despite its clinical importance, the underlying biological mechanisms driving PCD remain poorly understood. This study aimed to identify metabolomic …

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High hand-grip strength asymmetry and mortality risk in community-dwelling Japanese middle-aged and older adults: Results from the National Institute for Longevity Sciences-Longitudinal Study of Aging

Ricardo Aurélio Carvalho Sampaio, Yukiko Nishita, Chikako Tange, Shu Zhang et autres

BACKGROUND: Hand-grip strength (HGS) asymmetry may represent an indicator of overall health, yet its relationship with mortality risk remains underexplored at different cut-offs and populations. We aimed to investigate the association between HGS asymmetry and all-cause mortality in Japanese adults. METHODS: Overall, …

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Association of second-hand smoke exposure combined with cigarette smoking and the development of depressive symptoms among middle-aged and older adults in Japan: 20-year population-based cohort study

Wei‐Min Chu, Yukiko Nishita, Chikako Tange, Shu Zhang et autres

BACKGROUND: An association between second-hand smoke exposure and depressive symptoms has been reported; however, further research is needed for clarity. AIMS: This 20-year prospective cohort study aimed to longitudinally explore the relationships of smoking and second-hand smoke exposure with incident depressive symptoms …

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