Rui Liu

Towards mitigating helium damage in nano-crystal iron and tungsten: A strategy based on the dual trap-channel functionality of grain boundaries tuned by their crystallographic character

Fangqing Qian, Xiaolin Li, He Tong, Binbin Fan et autres

Abstract Nuclear fusion structural materials in critical components like blanket and first-wall are subjected to intense helium (He) generation, causing severe microstructural degradation that limits operational lifetime. Nanocrystalline microstructures have emerged as a promising route toward healing displacement damage. However, the theoretical …

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Network pharmacological analysis, Mendelian randomization analysis and animal experimental reveal the mechanism of Wenxin Granules in inhibiting heart failure after myocardial infarction: apoptosis and inflammation

Fuyuan Zhang, Baohua Li, Rui Liu, Yixin Liu et autres

Background: Apoptosis and inflammation are the key pathological mechanisms of heart failure after myocardial infarction (MI-HF). Wenxin Granules (WXG), an effective compound that has been used clinically for more than 20 years, could improve cardiac function, lipids and blood rheology in patients …

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Enhancement mechanism of erosion resistance of corundum-mullite saggers by step-like structure of anorthite

Zhenying Liu, Tingting Pan, Shaofeng Dong, Shouwu Huang et autres

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Hip Pain- When A Fall Is Not Just A Fall

Cory J. Fernandes, Rui Liu

HISTORY: A 17-year-old African American female with Sickle Cell Disease presents to the clinic for right hip pain after a fall she had 1 week ago. Patient says she was pushed, doesn’t remember how she landed, but after falling, another individual then …

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3051eP Differences in genomic features between tumors with and without tertiary lymphoid structures

Rui Liu, Zhigang Ji, Xinghuan Wang, Ran Sun et autres

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763P Clinical validation of the blood-based multiplex methylation assay: ColonAiQ, as a diagnostic aid for early detection of colorectal cancer

Xiaoyan Zhou, Han Li, Wenjie Dai, Ruizhi Wang et autres

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Systematic changes in intestinal mucosal barrier function and related aspects of laying hens during the aging process

Qihang Hou, Rui Liu, Xiaojun Yang, Bingkun Zhang

1. Reveals systematic age-related decline in intestinal barrier integrity in laying hens, characterized by villus shortening, goblet cell loss, increased permeability, and tight junction disruption. 2. Identifies Treg-macrophage immune imbalance as a key driver of intestinal inflammaging, evidenced by decreased Treg-derived IL-10 …

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Pusa V1.0: Unlocking Temporal Control in Pretrained Video Diffusion Models via Vectorized Timestep Adaptation

Yaofang Liu, Aitor Artola, Yuxuan Hu, Xiaodong Cun et autres

The rapid advancement of video diffusion models has been hindered by fundamental limitations in temporal modeling, particularly the rigid synchronization of frame evolution imposed by conventional scalar timestep variables. While task-specific adaptations and autoregressive models have sought to address these challenges, they …

LncRNA DRAIC facilitates the progression of renal cell carcinoma by modulting the microRNA-145-3p/ABRACL pathway signaling

Shufei Wei, Jianzhi Su, Rui Liu, Xiaoyu Zhang et autres

This study aims to elucidate the functional mechanisms of LncRNA DRAIC in renal cell carcinoma, particularly its regulation of tumor progression via microRNA-145-3p and ABRACL. The downstream targets of LncRNA DRAIC were predicted using databases, and their interactions with microRNA-145-3p were experimentally …

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Ablation behavior of tungsten alloys under high-energy electron irradiation

Yue Ma, Shangming Chen, Lei Peng, Yongjie Sun et autres

Abstract In order to investigate ablation behavior caused by runaway electrons on plasma facing materials (PFMs), the high energy electron irradiation experiment with a pulse duration of 0.6 µs at room temperature was performed. Specimens of ITER-grade tungsten (W), W-0.5 wt% ZrC …

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Orbital myoepithelial carcinoma: implications for diagnosis and treatment strategies

Jing Li, Nan Wang, Ke Feng, Tingting Ren et autres

BACKGROUND: Given the rarity orbital myoepithelial carcinoma (OMC) and the paucity of current evidence characterizing its clinical profile, this study aims to summarize the clinical features and prognostic outcomes of OMC. METHODS: This retrospective cohort study analyzed a consecutive series of 12 …

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Migraine and cardiovascular disease: A two-sample Mendelian randomization study

Yan Lu, Mengmeng Wang, Rui Li, Hongxiang Gao et autres

This study investigates the causal association between migraine and cardiovascular disease from a genetic perspective based on the Mendelian randomization analysis (MR) method. Single nucleotide polymorphism (SNPs) loci were used as genetic instrumental variables (IVs) to analyze potential causal relationships between exposure …

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