Yong Nam Han

GABA signaling in NG2 glia mediates empathy-like behavior under observational social defeat

Yujin Jian, Shengyu Jin, Peng Liu, Xiaoli Zheng et autres

Empathy, ranging from emotional contagion to consolation, is central to social cognition. While neural mechanisms of observed pain are well studied, how witnessing trauma affects empathy-related behaviors remains unclear. Using an observational social defeat (OSD) model, we find that OSD-exposed mice display …

cn, pt (code pays fourni par la source)

Inosine Ameliorates the Injurious Microenvironment for Oligodendrocyte Precursor Cells by Suppressing Microglial Activation and Neuroinflammation In Vitro

Yong Nam Han, Juan Chen, Peilian Wang, Jinping Sun et autres

cn (code pays fourni par la source)

Synthesis-enabled conformational assignment of natural N -acyl l -phenylalanine derivatives from freshwater sponge–associated Micromonospora sp. MS-62

Jiyool Kim, Jueun Kang, Yong Nam Han, Jinchan Sim et autres

single-crystal X-ray diffraction. This synthesis clarifies the stereochemistry of this natural product class and facilitates future exploration of structure-activity relationship.

kr (code pays fourni par la source)

Delayed tracheal injury following total thyroidectomy: case report and literature review

Qiang Gao, Xiaorui Fan, Wenjian Xu, Pengfei Gu et autres

A 51-year-old woman developed extensive subcutaneous emphysema on postoperative day 7 following total thyroidectomy with central lymph node dissection for thyroid cancer, indicating delayed tracheal injury. Emergency surgery revealed rupture of inter-tracheal ring ligaments and connective tissue, resulting in a necrotic 3 …

cn (code pays fourni par la source)

One-step engineered multifunctional gauze: On-demand antibiosis, accelerated hemostasis and angiogenesis for tissue regeneration

Xue Yang, Jin Shi, Lan Zhang, Xiaojing Zhang et autres

cn (code pays fourni par la source)

Characterization of terpene extract from Cannabis sativa flower and evaluation of its anti-melanogenetic effect in melan-a cells

Yong Nam Han, Banzragch Dorjsembe, Pahn‐Shick Chang, Taejung Kim et autres

Inhibition of melanogenesis is of major interest in the cosmetic industry. The mechanism underlying melanogenesis includes regulating tyrosinase by activating various signaling pathways, such as protein kinase A and C pathways. Natural material-based agents have recently gained attention as alternative medicines to …

kr, ca (code pays fourni par la source)

Nanozyme Coating-Mediated Mitochondrial Metabolic Reprogramming of Macrophages for Immunomodulatory Osseointegration in Rheumatoid Arthritis Case

Shimeng Chen, Xiaoqi Liu, Wenhui Zhang, Bo Li et autres

Conventional titanium (Ti)-based implants often fail to achieve osseointegration in bone defects accompanied by rheumatoid arthritis (RA), primarily due to the RA pathological microenvironment, characterized by elevated reactive oxygen species (ROS) levels and hypoxia. This microenvironment induces mitochondria dysfunction and intracellular Ca …

cn, us (code pays fourni par la source)

“Sandwich” structured nanorods for timely antibiosis, immunoregulation and neuroangiogenesis to accelerate osteogenesis of Zn-based implants in diabetics

Xue Yang, Lan Zhang, Mengting Mao, Shengda Wu et autres

cn (code pays fourni par la source)

Piezoelectric dual-network tough hydrogel with on-demand thermal contraction and sonopiezoelectric effect for promoting infected-joint-skin-wound healing via FAK and AKT signaling pathways

Jinlong Luo, Zhen Liang, Xin Zhao, Shengfei Huang et autres

The dynamic and whole stage management of infected wound healing throughout the entire repair process, including intelligent on-demand wound closure and the regulation of the transition from bactericidal to reparative phases, remains a major challenge. This study develops sonopiezoelectric-effect-mediated on-demand reactive-oxygen-species release …

cn (code pays fourni par la source)

An “all-in-one” therapeutic platform for programmed antibiosis, immunoregulation and neuroangiogenesis to accelerate diabetic wound healing

Xue Yang, Lan Zhang, Jun Chen, Dayan Ma et autres

cn (code pays fourni par la source)

A Targeted Core–Shell ZIF-8/Au@Fe3O4 Platform with Multiple Antibacterial Pathways for Infected Skin Wound Regeneration

Jing Zhang, Xue Yang, Lan Zhang, Jun Chen et autres

Bacterial infections seriously retard skin wound healing. To enhance the antibacterial efficiency and subsequent skin regeneration, a core–shell structured therapeutic platform, named FZAM, was designed with multiple antimicrobial pathways. FZAM consists of nanosized Fe 3 O 4 as the core and ZIF-8 …

cn (code pays fourni par la source)

Network‐Remodeling, Electroactive and Antibacterial Cryogel with Tissue Sealing and Pro‐Coagulant Activity for Hemostasis and Skin Wound Healing

Jinlong Luo, Zhengying Wu, Xin Zhao, Lipeng Qiao et autres

Abstract Developing network‐remodeling, electroactive and antibacterial cryogel with tissue sealing and pro‐coagulant activity for wound repair and hemostasis remains challenging. Here, quaternized chitosan‐graft‐polyaniline (QCSP), oxidized dextran (OD), and benzaldehyde‐terminated Pluronic F127 are used to prepare cryogel dressings (QP/OD/PF) with network remodeling, electroactivity, …

cn, sg, fr (code pays fourni par la source)