Xiang Wang

SlideChat is a multimodal generative artificial intelligence assistant for whole-slide computational pathology across cancer types

Ying Chen, Chenglong Ma, Qiongqiong Li, Fang Yan et autres

cn, us (code pays fourni par la source)

Thermal and dielectric properties of dual crosslinking network of epoxy cured with active ester containing benzocyclobutene groups and silicon-containing branched chains

Yunhong Liao, Xiang Wang, Yue He, Shuang Xia et autres

In situ generated modulus-gradient nanodomains for high-strength, tough and heat-resistant bismaleimide resins and carbon fiber composites

Fei Chen, Lei Wang, Jing Peng, Yang Zhang et autres

fr (code pays fourni par la source)

Sustainable vanillin-based epoxy networks with triple dynamic covalent bonds for low-temperature reprocessing and photothermal coating healing

Lei Wang, Fengqian Chen, Junliang He, Xiang Wang et autres

fr (code pays fourni par la source)

NLRP14 modulates the activity of E3 ubiquitin ligases during the oocyte-to-embryo transition

Sibei Liu, Qianqian Qi, Pengliang Chi, Haizhan Jiao et autres

NLRP14 is an essential maternal factor for mammalian embryonic development. Maternal ablation of NLRP14 in mice impairs DNA demethylation and calcium homeostasis in zygotes, causing early embryonic arrest. However, the underlying biochemical events remain largely unknown. Here, we identified two binding partners …

cn (code pays fourni par la source)

Molecular basis for the inhibition of de novo DNA methylation by TCL1A

Qingting Liu, Jinhong Li, Xiaoxiao Wang, Yaozong Li et autres

DNA methyltransferases DNMT3A/B mediate de novo DNA methylation, essential for embryonic development and cell fate determination. Dysregulation of DNMT3A/B causes developmental defects and tumorigenesis. TCL1A is critical for embryogenesis but promotes lymphomagenesis when deregulated. Previous studies suggested TCL1A binds DNMT3A/B and inhibits …

cn, se (code pays fourni par la source)

The maternal PADI6–UHRF1–UBE2D complex regulates ubiquitination during oocyte maturation and embryogenesis

Jinhong Li, Yuechao Lu, Zhili Xia, Pengliang Chi et autres

cn (code pays fourni par la source)

WITHDRAWN: A significant effect of the HUWE1 copy number on autistic spectrum disorder and the development of zebrafish

Haojuan Wu, Yan Liang, Juan Li, Xueguang Zhang et autres

cn, hu (code pays fourni par la source)

Structural-guided identification of two modulators of β−1,3-glucan synthase FKS1

Jialu Li, Jian Li, Angqi Zhu, Xinli Dai et autres

FKS1 is a β−1,3-glucan synthase critical for fungal cell wall formation and a target for antifungal drugs such as echinocandin and ibrexafungerp. However, the mechanisms regulating FKS1 activity remain largely unknown. Here, we reveal that transfer RNA (tRNA) acts as an endogenous …

cn, kr, us (code pays fourni par la source)

Furin‐Mediated Cleavage of Zona Pellucida Proteins Is Essential for Oocyte Development

Tiechao Ruan, Xiang Wang, Xueguang Zhang, Yan Wang et autres

Zona pellucida (ZP) proteins, essential for oocyte development, undergo posttranslational regulation through furin-mediated cleavage. Nevertheless, our understanding of the functional significance of furin-mediated cleavage of ZP proteins in female reproduction remains limited. Here, using mouse models with disrupted furin cleavage sites in …

cn (code pays fourni par la source)

NLRP14 modulates the activity of E3 ubiquitin ligases during the oocyte-to-embryo transition

Dong Deng, Sibei Liu, Qianqian Qi, Pengliang Chi et autres

cn, hk (code pays fourni par la source)

Structural assembly of the subcortical maternal complex SCMC

Guojin Ou, Haizhan Jiao, Zhuo Han, Jinhong Li et autres

cn (code pays fourni par la source)