Ke Wang

Metagenomic Next-Generation Sequencing Improves Pathogen Detection and Rational Use in Patients with Infectious Fever: A Retrospective Study

Daiping Su, Shufang Pan, Jiahui Pang, Fei Tang et autres

cn (code pays fourni par la source)

Stimuli-responsive microneedles: Engineered solutions for multifaceted diabetic wound healing

F M Wang, J Zhang, Bing Han, Ming Chen et autres

Diabetic wounds are among the most common complications in patients with diabetes, often occurring in the lower extremities and manifesting as diabetic foot ulcers. These wounds are often associated with issues such as infection, peripheral artery disease, hyperglycemia, and hypoxia, making them …

cn (code pays fourni par la source)

Enterprise-related Charges: Practical Difficulties and Rule-of-law Supervision Pathways

Ke Wang

涉企收费作为优化营商环境的重要组成部分，在概念上与行政收费具有高度关联性，但二者并非等同关系。涉企收费的要件具有行政法上的特征，包括但不限于主体、依据、范围。当下涉企收费的治理面临依据、主体、范围上的问题。法治监督作为中国特色社会主义法治体系的重要组成部分，可对涉企收费的依据、主体、范围所涉及的行政权进行制约与监督，并通过公开监督落实，解决面临的现实困境。具体可通过法治导向、公开监督、行政检察进行法治监督的路径构建，确保涉企收费治理的完善。

Who Judges the Judge? LLM Jury-on-Demand: Building Trustworthy LLM Evaluation Systems

Xiaochuan Li, Ke Wang, Girija Gouda, Shubham Choudhary et autres

As Large Language Models (LLMs) become integrated into high-stakes domains, there is a growing need for evaluation methods that are both scalable for real-time deployment and reliable for critical decision-making. While human evaluation is reliable, it is slow and costly. Single LLM …

Effects of Histone Deacetylases (HDACs) in Programmed Cell Death: Execution Mechanism and Regulatory Pathways

Qi Wu, Yingjie Zhao, Qiuxia Yu, Jie Ding et autres

Histone deacetylases (HDACs) are zinc- or NAD + -dependent enzymes that play a key role in controlling diverse cellular processes by removing acetyl groups from the lysine residues of both histone and nonhistone proteins. In humans, there are 18 HDAC enzymes. Programmed …

cn (code pays fourni par la source)

Exercise attenuates hepatic lipid accumulation via VDR/AMPK-mediated autophagy activation in vitamin D-deficient mice

Jing‐Jing Liu, Yun Niu, Xiaoning Cui, Shiqi Lu et autres

cn (code pays fourni par la source)

Tumor PLA2G10 restrains CD4+ T cell activation in lung adenocarcinoma via enhancing arachidonic acid secretion

Ye Tian, Qingzhi Ma, Hao Wang, Ming-Yan Shi et autres

cn (code pays fourni par la source)

Shikonin-Loaded Nanoparticles Attenuate Particulate Matter-Induced Skin Injury by Inhibiting Oxidative Stress and Inflammation

F. Huang, Qinghua Tang, Ke Wang, Lingmei Zhou et autres

Exposure to fine particulate matter (PM2.5) poses a major threat to skin health, yet effective prevention strategies remain limited. Shikonin, a naphthoquinone derived from Lithospermum erythrorhizon, exhibits potent antioxidant and anti-inflammatory activities. However, its therapeutic application is limited by low bioavailability. To …

cn (code pays fourni par la source)

Texture Analysis of Uterine‐Derived T2‐Weighted Imaging in Patients With Primary Dysmenorrhea Across Different Menstrual Phases

Ke Wang, Huiping Liu, Meiling Shang, Jing Yang et autres

PURPOSE: Primary dysmenorrhea (PDM) affects 45%-95% of menstruating women. However, the mechanism of PDM is still unclear; abnormal uterine structure may be one of the causes of PDM. But the subtle structural changes of the uterus during the menstrual phase cannot be …

cn (code pays fourni par la source)

Predictive model of sperm DNA fragmentation in infertile men based on lifestyle factors

Mengjia Pan, You Zhang, Ningxin Qin, Yan Xu et autres

Objective: This study aimed to investigate the influence of lifestyle factors on the sperm DNA fragmentation index (DFI) in infertile men, and to develop and validate a predictive model for identifying individuals at risk of abnormal DFI. Methods: A total of 746 …

cn (code pays fourni par la source)

Decoding Hypercarotenemia: Integrating Pathophysiology, Clinical Recognition, and Precision Management

Zhilin Wang, Jun Xu, Guangming Xu, Yanguang Sha et autres

Hypercarotenemia represents a complex metabolic phenotype characterized by supraphysiological circulating carotenoid concentrations exceeding 300 μg/dL for β-carotene, manifesting as distinctive cutaneous xanthochromia with preserved scleral clarity - a critical differentiating feature from hepatobiliary dysfunction. The contemporary surge in detection rates, which has …

cn (code pays fourni par la source)

Aerobic exercise attenuates intramyocellular lipid accumulation by upregulating vitamin D receptor

Ke Wang, Jinghua Zhang, Xiaoning Cui, Yun Niu et autres

cn (code pays fourni par la source)