Alterations in Trace Element and Metabolite Profiles by Graphene Nanosheets and Multi‐Walled Carbon Nanotubes as Soil Contaminants in Foot Tissues of the Chinese White Jade Snails ( Achatina fulica )
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Le résumé fourni par la source
The increasing applications of carbon nanomaterials (NMs) raise concerns about their potential as soil contaminants, yet predictive models for NM-related soil contamination risks remain scarce. This study established the Chinese white jade snails (Achatina fulica) as a novel model to assess the toxicity of two representative carbon-based NMs, namely, graphene nanosheets (GNSs) and multi-walled carbon nanotubes (MWCNTs). Snails of 1-2 weeks old were exposed to coconut substrate containing 1% NMs for 28 days. While the exposure showed no significant effects on food consumption, weight gain, or structural alterations in foot tissues (epidermis, muscle layer, or mucous glands), inductively coupled plasma mass spectrometry (ICP-MS) analysis of foot tissue demonstrated that MWCNTs, but not GNSs, significantly reduced Fe and Co levels. Metabolomic profiling revealed more pronounced metabolic perturbations in MWCNT-exposed snails compared to GNS-exposed counterparts. Both NMs upregulated phosphatidylinositol (38:4). MWCNTs additionally increased phosphatidylcholine (PC) (44:10), tyrosine, gamma-glutamylphenylalanine (38:4), and phenylalanine, while decreasing 15-deoxy-PGJ2 and PC (40:7). Pathway enrichment analysis identified eight significantly affected KEGG pathways exclusively in MWCNT-exposed snails, encompassing lipid metabolism (glycerophospholipid, arachidonic acid, and alpha-linolenic acid metabolism), amino acid biosynthesis and metabolism (phenylalanine/tyrosine/tryptophan biosynthesis and metabolism), and ubiquinone and other terpenoid-quinone biosynthesis. These findings highlight the utility of A. fulica for evaluating NM-induced trace element dysregulation and metabolic reprogramming in soil ecosystems.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Alterations in Trace Element and Metabolite Profiles by Graphene Nanosheets and Multi‐Walled Carbon Nanotubes as Soil Contaminants in Foot Tissues of the Chinese White Jade Snails ( <scp> <i>Achatina fulica</i> </scp> )
- Date Crossref
- 25/11/2025
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of South China pays non établi dans la noticeUniversité ou école supérieure
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Shanghai Optical Instrument Research Institute pays non établi dans la noticeStructure de recherche
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Southern Medical University NMPA Key Laboratory for Safety Evaluation of Cosmetics pays non établi dans la noticeUniversité ou école supérieure
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Sun Yat-sen University pays non établi dans la noticeUniversité ou école supérieure
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School of Public Health Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards pays non établi dans la noticeUniversité ou école supérieure
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Shanghai AB Sciex Analytical Instrument Trading Co. Ltd. Shanghai China pays non établi dans la noticeEntreprise
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Zhongshan School of Medicine Sun Yat‐Sen University Guangzhou China Guangdong Province Translational Forensic Medicine Engineering Technology Research Center pays non établi dans la noticeUniversité ou école supérieure
University of South China, Shanghai Optical Instrument Research Institute et NMPA Key Laboratory for Safety Evaluation of Cosmetics — Southern Medical University, avec 4 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.