Xu Liu

Insights into vitamin C in musculoskeletal physiology and disorders: mechanisms and translational perspectives

Xu Liu, Bo Chen, Qingnan Feng, Shitong Wang et autres

Vitamin C (VC) is an essential micronutrient involved in diverse biological processes, including redox homeostasis, energy metabolism, collagen synthesis, epigenetic regulation, and immune modulation. Increasing evidence indicates that VC plays important roles in the musculoskeletal system, which is essential for structural support, …

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Cross‑kingdom antiviral action of Scutellaria baicalensis Georgi and Chrysanthemum indicum L. miRNAs: A novel strategy against duck viral hepatitis

Mengxin Hu, Zhipeng Chen, Kexin Wang, Xu Liu et autres

Duck viral hepatitis (DVH) requires novel therapeutic strategies. This study investigated antiviral miRNAs in separate decoctions of Scutellaria baicalensis Georgi and Chrysanthemum indicum L. High-throughput sequencing identified 14 highly expressed miRNAs, which were chemically synthesized for functional validation. CCK8 assay quantified cytoprotection …

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Optimized Decision Model for Soil-Moisture Control Lower Limits and Evapotranspiration-Based Irrigation Replenishment Ratios Based on AquaCrop-OSPy, PyFAO56, and NSGA-II and Its Application

Xu Liu, Zhaolong Liu, Wenhui Tang, Zhichao An et autres

As water resources are becoming increasingly scarce in the North China Plain, irrigation strategies that simultaneously improve grain yield and reduce irrigation water input are needed for winter wheat (Triticum aestivum L.) production. Current irrigation decision rules are based either on fixed …

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Phosphorus fertilization shapes rhizosphere beneficial microbial communities and soil–plant relations in arid cotton fields of Xinjiang, China

Bin Peng, Shuai Zhao, C. P. Liu, Wenxuan Mai et autres

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Community Assembly Mechanisms Underlying Divergent Responses of Indica and Japonica Rice Rhizosphere Microbiota to Drought Stress

Sihan Zhou, Junguo Bi, Sheng Ming Zhou, Lijun Luo et autres

Drought stress markedly reduces rice yield, with notable genotypic variation in drought tolerance. While the rhizosphere microbiome is regarded as the second genome of plants, how the indica and japonica rice rhizosphere microbial communities respond to deficit irrigation and their relationship with …

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Flight capacity and wingbeat frequency of Mythimna loreyi (Lepidoptera: Noctuidae)

Limei He, Xiaoting Sun, Yanni Tan, Yatao Zhou et autres

The maize caterpillar, Mythimna loreyi (Duponchel, 1827) (Lepidoptera: Noctuidae), is an important migratory pest for agricultural production in Asia, but its flight performance remains poorly understood. Here, we utilized a computer-monitored flight mill system and a stroboscope to assess how adult age, …

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Reovirus infection results in rice rhizosphere microbial community reassembly through metabolite-mediated recruitment and exclusion

Zhanbiao Li, H. Xie, Cuiping Mo, Bixia Qin et autres

BACKGROUND: Microbial assembly plays a critical role in ecosystem function and biodiversity. While numerous studies have explored the effect of abiotic factors on the belowground community assembly, much less is known about the role of biotic interactions, particularly viral infections, in shaping …

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Single-shot sub-λ⁄10 label-free super-resolution microscopy based on mixed spatial-frequency-shift demodulation

Haonan Zhang, Xu Liu, Qing Yang

Spatial-frequency-shift (SFS) super resolution imaging for label-free sample based on the wavevector modulation has its limit in the weak scattering intensity of the high-frequency propagation field, which leads to the decrease in the quality of ultra-high-resolution images. The enhanced illumination field supported …

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Engineering Targeted Gene Delivery Systems for Primary Hereditary Skeletal Myopathies: Current Strategies and Future Perspectives

Jiahao Wu, Yimin Hua, Yanjiang Zheng, Xu Liu et autres

Skeletal muscle, constituting ~40% of body mass, serves as a primary effector for movement and a key metabolic regulator through myokine secretion. Hereditary myopathies, including dystrophinopathies (DMD/BMD), limb–girdle muscular dystrophies (LGMD), and metabolic disorders like Pompe disease, arise from pathogenic mutations in …

Deep reinforcement learning based on Bayesian optimization in UAV path planning

Xu Liu, Xiuhe Li, Haiyan Zhang, Lizhang Liu et autres

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Advances in mRNA-LNP lung-targeted delivery strategies

Xu Liu, Shuhan Ji, Fuchun Yang, Jian You et autres

The lung, a vital organ for homeostasis, is vulnerable to various diseases that challenge healthcare systems due to limited treatment options. Fortunately, mRNA-based gene therapy offers a promising solution, demonstrating high efficiency and safety across applications in vaccines, protein replacement therapy, and …

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Rice-fish co-culture improves carp (Cyprinus carpio) quality by modulating the gut microbiota and metabolites

Zhijuan Nie, Xiaotong Xu, Yanhan Ji, Ping Gao et autres

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