Accès ouvert
2025
article
OpenAlex
Elham Hasheminasabgorji, Huey‐Miin Chen, Taylor A. Gatesman, Subhi Talal Younes et autres
It is currently understood that the characteristic loss of the repressive histone mark H3K27me3 in PFA ependymoma and diffuse midline glioma (DMG) are caused by complementary mechanisms mediated by EZHIP and the oncohistone H3K27M, respectively. To support the complementarity of these mechanisms, …
ca, us
(code pays fourni par la source)
2025
article
OpenAlex
Mansour Poorebrahim, David S. Jung, Holly Lee, Sacha Benaoudia et autres
Accès ouvert
2025
preprint
OpenAlex
Elham Hasheminasabgorji, Huey‐Miin Chen, Taylor A. Gatesman, Subhi Talal Younes et autres
ABSTRACT It is currently understood that the characteristic loss of the repressive histone mark H3K27me3 in PFA ependymoma and diffuse midline glioma (DMG) are caused by complementary mechanisms mediated by EZHIP and the oncohistone H3K27M, respectively. To support the complementarity of these …
ca, us
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Sejal Chikhale, Mansour Poorebrahim, Holly Lee, Elham Hasheminasabgorji et autres
Abstract Multiple Myeloma (MM) is an incurable hematological malignancy originating from abnormal plasma cells in the bone marrow. A common genetic abnormality in MM is the gain or amplification of chromosome arm 1q (chr1q), present in 30-40% of MM patients and typically …
ca
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Michael J.G. Johnston, John J. Y. Lee, Bo Hu, Ana Antic Nikolic et autres
Posterior fossa group A (PFA) ependymoma is a lethal brain cancer diagnosed in infants and young children. The lack of driver events in the PFA linear genome led us to search its 3D genome for characteristic features. Here, we reconstructed 3D genomes …
ca, kr, us, jp, hu, pl
(code pays fourni par la source)