Plasma cell identity escape drives resistance to anti-BCMA T-cell–redirecting therapy in multiple myeloma
Francesco Maura, Ciara L. Freeman, Kylee Maclachlan, Marta Larráyoz et autres
2 citationsbioRxiv (Cold Spring Harbor Laboratory)
Holly Lee
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126Publications signalées
909Citations signalées
3Affiliations récentes
Institutions déclarées
Domaines associés
Multiple Myeloma Research and TreatmentsPeptidase Inhibition and AnalysisProtein Degradation and InhibitorsCAR-T cell therapy researchMonoclonal and Polyclonal Antibodies Research
Publications récentes
B7-H3 nanobody-based CAR T cells control multiple myeloma growth, while dual BCMA/B7-H3 CAR T cells overcome antigen escape
Arne Van der Vreken, Fien Meeus, Chenggong Tu, Lauren van den Broecke et autres
8 citationsJournal of Hematology & Oncology
Supplementary Tables S1-S2 from Timing Genomic Antigen Loss in Multiple Myeloma Treated with T Cell–Redirecting Immunotherapies
Marios Papadimitriou, Sungwoo Ahn, Benjamin Diamond, Holly Lee et autres
0 citations
Data from Timing Genomic Antigen Loss in Multiple Myeloma Treated with T Cell–Redirecting Immunotherapies
Marios Papadimitriou, Sungwoo Ahn, Benjamin Diamond, Holly Lee et autres
0 citations
Supplementary Figures S1-S3 from Timing Genomic Antigen Loss in Multiple Myeloma Treated with T Cell–Redirecting Immunotherapies
Marios Papadimitriou, Sungwoo Ahn, Benjamin Diamond, Holly Lee et autres
0 citations
Evidence for pre-existing myeloma cells with a gene expression pattern associated with resistance to BCMA CAR T cells.
Angélica M. Amanso, Karanpreet Singh Bhatia, Mackenzie Mekler, James Ackley et autres
0 citationsBlood
Antigen-dependent clonal sweep with sequential or combinatory anti-myeloma T cell engagers
Holly Lee, Sungwoo Ahn, Deeksha Vishwamitra, Sheri Skerget et autres
4 citationsBlood
Enhanced efficacy of TRAIL or TRAIL-CD28 chimera armored anti-BCMA CAR T cells in multiple myeloma
Mansour Poorebrahim, David Jung, Holly Lee, Sacha Benaoudia et autres
0 citationsBlood
Deletion of TRAF3 and CYLD and NIK amplification activates NF-kb signalling and drives resistance to T cell based therapies in multiple myeloma by suppressing T cell activity
David Jung, Sacha Benaoudia, Holly Lee, Sungwoo Ahn et autres
0 citationsBlood
The evolution to hepta-refractory myeloma involves sequential loss of CD38, BCMA and GPRC5D
Christine Riedhammer, Marietta Truger, Holly Lee, Lisa Leypoldt et autres
1 citationBlood
Timing Genomic Antigen Loss in Multiple Myeloma Treated with T Cell–Redirecting Immunotherapies
Marios Papadimitriou, Sungwoo Ahn, Benjamin Diamond, Holly Lee et autres
11 citationsBlood Cancer Discovery
A Comprehensive Map of Genomic Drivers of Resistance to Anti-BCMA Immunotherapies in Multiple Myeloma
Francesco Maura, Ciara L. Freeman, Kylee Maclachlan, Marta Larráyoz et autres
0 citationsClinical Lymphoma Myeloma & Leukemia
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